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Michael Dorrell, Ph.D.

Assistant Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
dorrell@scripps.edu
(858) 784-2930

Education

Ph.D. (Biomedical Research), The Scripps Research Institute, Scripps Graduate Program 2003
B.A. (Chemistry, Math), Simpson College 1998

Professional Experience

2009-2017 Assistant Professor Adjunct, Cell and Molecular Biology (CMB), The Scripps Research Institute
2012-2015 Associate Professor, Point Loma Nazarene University
2013-2014 Senior Staff Scientist, The Lowy Medical Research Institute (LMRI)
2010-2012 Research Consultant, EyeCyte
2009-2012 Assistant Professor, Point Loma Nazarene University
2007-2009 Professor Adjunct, University of San Diego
2003-2009 Research Associate, The Scripps Research Institute
2004-2005 Research Scientist, Angiosyn
2003-2004 Research Consultant, Angiosyn
2000-2001 Research Consultant, Nanogen

Selected References

All Publications

Usui, Y., Westenskow, P. D., Murinello, S., Dorrell, M. I., Scheppke, L., Bucher, F., Sakimoto, S., Paris, L. P., Aguilar, E. & Friedlander, M. Angiogenesis and eye disease. (2015). Annual Review of Vision Science, 1, 155.

Usui, V., Westenskow, P. D., Kurihara, T., Aguilar, E., Sakimoto, S., Paris, L. P., Wittgrove, C., Feitelberg, D., Friedlander, M. S. H., Moreno, S. K., Dorrell, M. I., Friedlander, M. Neurovascular crosstalk between interneurons and capillaries is required for vision. (2015). Journal of Clinical Investigation, 125(6), 2335-2346.

Dorrell, M. I., Marcacci, M., Bravo, S., Kurz, T., Tremblay, J. & Rusing, J. C. Ex ovo model for directly visualizing chick embryo development. (2012). American Biology Teacher, 74(9), 628-634.

Weidemann, A., Krohne, T. U., Aguilar, E., Kurihara, T., Takeda, N., Dorrell, M. I., Simon, M. C., Haase, V. H., Friedlander, M. & Johnson, R. S. Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. (2010). Glia, 58(10), 1177-1185. PMCID: PMC2993327.

Dorrell, M. I., Aguilar, E., Jacobson, R., Trauger, S. A., Friedlander, J., Siuzdak, G. & Friedlander, M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. (2010). Glia, 58(1), 43-54. PMCID: PMC2814838.

Dorrell, M. I., Aguilar, E., Jacobson, R., Yanes, O., Gariano, R., Heckenlively, J., Banin, E., Ramirez, G. A., Gasmi, M., Bird, A., Siuzdak, G., Friedlander, M. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. (2009). Journal of Clinical Investigation, 119(3), 611-623. PMCID: PMC2648679.

Aguilar, E., Dorrell, M. I., Friedlander, D., Jacobson, R. A., Johnson, A., Marchetti, V., Moreno, S. K., Ritter, M. R. & Friedlander, M. Ocular models of angiogenesis. (2008). Methods in Enzymology, 444, 115.

Friedlander, M., Dorrell, M. I., Ritter, M. R., Marchetti, V., Moreno, S. K., El-Kalay, M., Bird, A. C., Banin, E. & Aguilar, E. Progenitor cells and retinal angiogenesis. (2007). Angiogenesis, 10(2), 89-101.

Dorrell, M. I., Aguilar, E., Scheppke, L., Barnett, F. H. & Friedlander, M. Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis. (2007). Proceedings of the National Academy of Sciences of the United States of America, 104(3), 967-972. PMCID: PMC1764763.

Dorrell, M., Uusitalo-Jarvinen, H., Aguilar, E. & Friedlander, M. Ocular neovascularization: Basic mechanisms and therapeutic advances. (2007). Survey of Ophthalmology, 52(Suppl 1), S3-S19.