Publications

  1. Qiu, S.; Zhao, Z.; Wu, M.; Xue, Q.; Yang, Y.; Ouyang, S.; Li, W.; Zhong, L.; Wang, W.; Yang, R.; Wu, P.; Li, J. P. Use of Intercellular Proximity Labeling to Quantify and Decipher Cell-Cell Interactions Directed by Diversified Molecular Pairs. Science Advances 2022, 8 (51), eadd2337. https://doi.org/10.1126/sciadv.add2337.
  2. Stepanov, A. V.; Kalinin, R. S.; Shipunova, V. O.; Zhang, D.; Xie, J.; Rubtsov, Y. P.; Ukrainskaya, V. M.; Schulga, A.; Konovalova, E. V.; Volkov, D. V.; Yaroshevich, I. A.; Moysenovich, A. M.; Belogurov, A. A.; Zhang, H.; Telegin, G. B.; Chernov, A. S.; Maschan, M. A.; Terekhov, S. S.; Wu, P.; Deyev, S. M. Switchable Targeting of Solid Tumors by BsCAR T Cells. Proceedings of the National Academy of Sciences 2022, 119 (46). https://doi.org/10.1073/pnas.2210562119.
  3. Wu, P. The Nobel Prize in Chemistry 2022: Fulfilling Demanding Applications with Simple Reactions. ACS Chemical Biology 2022, 17 (11), 2959–2961. https://doi.org/10.1021/acschembio.2c00788.
  4. Tong, X.; Ru, Y.; Fu, J.; Wang, Y.; Zhu, J.; Ding, Y.; Lv, F.; Yang, M.; Wei, X.; Liu, C.; Liu, X.; Lei, L.; Wu, X.; Guo, L.; Xu, Y.; Li, J.; Wu, P.; Gong, H.; Chen, J.; Wu, D. Fucosylation Promotes Cytolytic Function and Accumulation of NK Cells in B Cell Lymphoma. Frontiers in Immunology 2022, 13, 904693. https://doi.org/10.3389/fimmu.2022.904693.
  5. Hong, S.; Yu, C.; Wang, P.; Shi, Y.; Cao, W.; Cheng, B.; Chapla, D. G.; Ma, Y.; Li, J.; Rodrigues, E.; Narimatsu, Y.; Yates, J. R.; Chen, X.; Clausen, H.; Moremen, K. W.; Macauley, M. S.; Paulson, J. C.; Wu, P. Glycoengineering of NK Cells with Glycan Ligands of CD22 and Selectins for B-Cell Lymphoma Therapy. Angewandte Chemie (International Ed. in English) 2021, 60 (7), 3603–3610. https://doi.org/10.1002/anie.202005934.
  6. Kim, H.; Zhao, J.; Bae, J.; Klivansky, L. M.; Dailing, E. A.; Liu, Y.; Cappiello, J. R.; Sharpless, K. B.; Wu, P. Chain-Growth Sulfur(VI) Fluoride Exchange Polycondensation: Molecular Weight Control and Synthesis of Degradable Polysulfates. ACS Central Science 2021, 7 (11), 1919–1928. https://doi.org/10.1021/acscentsci.1c01015.
  7. Hong, S.; Yu, C.; Rodrigues, E.; Shi, Y.; Chen, H.; Wang, P.; Chapla, D. G.; Gao, T.; Zhuang, R.; Moremen, K. W.; Paulson, J. C.; Macauley, M. S.; Wu, P. Modulation of Siglec-7 Signaling via in Situ-Created High-Affinity Cis-Ligands. ACS Central Science 2021, 7 (8), 1338–1346. https://doi.org/10.1021/acscentsci.1c00064.
  8. Liu, Z.; Li, J. P.; Chen, M.; Wu, M.; Shi, Y.; Li, W.; Teijaro, J. R.; Wu, P. Detecting Tumor Antigen-Specific T Cells via Interaction-Dependent Fucosyl-Biotinylation. Cell 2020, 183 (4), 1117-1133.e19. https://doi.org/10.1016/j.cell.2020.09.048.
  9. Hong, S.; Grande, G.; Yu, C.; Chapla, D. G.; Reigh, N.; Yang, J.-Y.; Yang, Y.; Izumori, K.; Moremen, K. W.; Xie, J.; Wu, P. HFUT1-Based Live-Cell Assay to Profile α1-2-Fucoside-Enhanced Influenza Virus a Infection. ACS Chemical Biology 2020, 15 (4), 819–823. https://doi.org/10.1021/acschembio.9b00869.
  10. Hong, S.; Feng, L.; Yang, Y.; Jiang, H.; Hou, X.; Guo, P.; Marlow, F. L.; Stanley, P.; Wu, P. In Situ Fucosylation of the Wnt Co-Receptor LRP6 Increases Its Endocytosis and Reduces Wnt/β-Catenin Signaling. Cell Chemical Biology 2020, 27 (9), 1140-1150.e4. https://doi.org/10.1016/j.chembiol.2020.06.015.
  11. Li, S.; Li, G.; Gao, B.; Pujari, S. P.; Chen, X.; Kim, H.; Zhou, F.; Klivansky, L. M.; Liu, Y.; Driss, H.; Liang, D.-D.; Lu, J.; Wu, P.; Zuilhof, H.; Moses, J.; Sharpless, K. B. SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride. Nature Chemistry 2021, 13 (9), 858–867. https://doi.org/10.1038/s41557-021-00726-x.
  12. Xu, L.; Wu, P.; Dong, J. CHAPTER 1: New Polymers From SuFEx Click Chemistry: Syntheses and Perspective, in Synthetic Polymer Chemistry: Innovations and Outlook 2019, 1-31. https://doi.org/10.1039/9781788016469-00001.
  13. Zheng, Q.; Xu, H.; Wang, H.; Du, W.; Wang, N.; Xiong, H.; Gu, Y.; Noodleman, L.; Yang, G.; Sharpless, K. B.; Wu, P. Click Chemistry Expedited Radiosynthesis: Sulfur [18F] fluoride Exchange of Aryl Fluorosulfates. ChemRxiv 2019, Nov 15. https://doi.org/110.1021/jacs.0c09306.
  14. Hong, S.; Sahai‐Hernandez, P.; Chapla, D. G.; Moremen, K. W.; Traver, D.; Wu, P. Direct Visualization of Live Zebrafish Glycans via Single‐Step Metabolic Labeling with Fluorophore‐Tagged Nucleotide Sugars. Angewandte Chemie (International Ed. in English) 2019, 58 (40), 14327–14333. https://doi.org/10.1002/anie.201907410.
  15. Liu, F.; Wang, H.; Li, S.; Bare, G. A. L.; Chen, X.; Wang, C.; Moses, J. E.; Wu, P.; Sharpless, K. B. Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins. Angewandte Chemie (International Ed. in English) 2019, 58 (24), 8029–8033. https://doi.org/10.1002/anie.201902489.
  16. Tomita, T.; Wang, H.; Wu, P.; Weiss, L. M. Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite Toxoplasma Gondii by Using an Esterase-Ester Pair Technique. mSphere 2019, 4 (3), e00142-19. https://doi.org/10.1128/mSphere.00142-19.
  17. Hong, S.; Shi, Y.; Wu, N. C.; Grande, G.; Douthit, L.; Wang, H.; Zhou, W.; Sharpless, K. B.; Wilson, I. A.; Xie, J.; Wu, P. Bacterial Glycosyltransferase-Mediated Cell-Surface Chemoenzymatic Glycan Modification. Nature Communications 2019, 10 (1). https://doi.org/10.1038/s41467-019-09608-w.
  18. Liu, Z.; Meng, G.; Guo, T.; Dong, J.; Wu, P. Novel Approaches to Access Arylfluorosulfates and Sulfamoyl Fluorides Based on Sulfur (VI) Fluoride Exchange. Current Protocols in Chemical Biology 2019, 11 (2), e64. https://doi.org/10.1002/cpch.64.
  19. Liu, Y.; Hu, H.; Wang, J.; Zhou, Q.; Wu, P.; Yan, N.; Wang, H.-W.; Wu, J.-W.; Sun, L. Cryo-EM Structure of L-Fucokinase/GDP-Fucose Pyrophosphorylase (FKP) in Bacteroides Fragilis. Protein & Cell 2019, 10 (5), 365–369. https://doi.org/10.1007/s13238-018-0576-x.
  20. Li, J.; Chen, M.; Liu, Z.; Zhang, L.; Felding, B. H.; Moremen, K. W.; Lauvau, G.; Abadier, M.; Ley, K.; Wu, P. A Single-Step Chemoenzymatic Reaction for the Construction of Antibody-Cell Conjugates. ACS Central Science 2018, 4 (12), 1633–1641. https://doi.org/10.1021/acscentsci.8b00552.
  21. Zheng, T.; Xie, J.; Yang, Z.; Tao, P.; Shi, B.; Douthit, L.; Wu, P.; Lerner, R. A. Antibody Selection Using Clonal Cocultivation of Escherichia Coli and Eukaryotic Cells in Miniecosystems. Proceedings of the National Academy of Sciences 2018, 115 (27), E6145–E6151. https://doi.org/10.1073/pnas.1806718115.
  22. Lopez Aguilar, A.; Meng, L.; Hou, X.; Li, W.; Moremen, K. W.; Wu, P. Sialyltransferase-Based Chemoenzymatic Histology for the Detection of N- and O-Glycans. Bioconjugate Chemistry 2018, 29 (4), 1231–1239. https://doi.org/10.1021/acs.bioconjchem.8b00021.
  23. Briard, J. G.; Jiang, H.; Moremen, K. W.; Macauley, M. S.; Wu, P. Cell-Based Glycan Arrays for Probing Glycan–Glycan Binding Protein Interactions. Nature Communications 2018, 9 (1). https://doi.org/10.1038/s41467-018-03245-5.
  24. Liu, Z.; Li, J.; Li, S.; Li, G.; Sharpless, K. B.; Wu, P. SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization. Journal of the American Chemical Society 2018, 140 (8), 2919–2925. https://doi.org/10.1021/jacs.7b12788.
  25. Rouhanifard, S. H.; Lopez Aguilar, A.; Meng, L.; Moremen, K. W.; Wu, P. Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids. Cell Chemical Biology 2018, 25 (4), 439-446.e5. https://doi.org/10.1016/j.chembiol.2018.01.010.
  26. Jiang, H.; López-Aguilar, A.; Meng, L.; Gao, Z.; Liu, Y.; Tian, X.; Yu, G.; Ovryn, B.; Moremen, K. W.; Wu, P. Modulating Cell-Surface Receptor Signaling and Ion Channel Functions by in Situ Glycan Editing. Angewandte Chemie (International Ed. in English) 2018, 57 (4), 967–971. https://doi.org/10.1002/anie.201706535.
  27. Schneider, M.; Kumar, V.; Nordstrøm, L. U.; Feng, L.; Takeuchi, H.; Hao, H.; Luca, V. C.; Garcia, K. C.; Stanley, P.; Wu, P.; Haltiwanger, R. S. Inhibition of Delta-Induced Notch Signaling Using Fucose Analogs. Nature Chemical Biology 2018, 14 (1), 65–71. https://doi.org/10.1038/nchembio.2520.
  28. Lopez Aguilar, A.; Gao, Y.; Hou, X.; Lauvau, G.; Yates, J. R.; Wu, P. Profiling of Protein O-GlcNAcylation in Murine CD8+ Effector- and Memory-like T Cells. ACS Chemical Biology 2017, 12 (12), 3031–3038. https://doi.org/10.1021/acschembio.7b00869.
  29. Aguilar, A. L.; Hou, X.; Wen, L.; Wang, P. G.; Wu, P. A Chemoenzymatic Histology Method for O-GlcNAc Detection. ChemBioChem 2017, 18 (24), 2416–2421. https://doi.org/10.1002/cbic.201700515.
  30. Ovryn, B.; Li, J.; Hong, S.; Wu, P. Visualizing Glycans on Single Cells and Tissues-Visualizing Glycans on Single Cells and Tissues. Current Opinion in Chemical Biology 2017, 39, 39–45. https://doi.org/10.1016/j.cbpa.2017.04.018.
  31. Gao, B.; Zhang, L.; Zheng, Q.; Zhou, F.; Klivansky, L. M.; Lu, J.; Liu, Y.; Dong, J.; Wu, P.; Sharpless, K. B. Bifluoride-Catalysed Sulfur(VI) Fluoride Exchange Reaction for the Synthesis of Polysulfates and Polysulfonates. Nature Chemistry 2017, 9 (11), 1083–1088. https://doi.org/10.1038/nchem.2796.
  32. Zhu, H.; Chen, D.; Li, N.; Xu, Q.; Li, H.; He, J.; Wang, H.; Wu, P.; Lu, J. Fabrication of Photocontrolled Surfaces for Oil/Water Separation through Sulfur(VI) Fluoride Exchange. Chemistry (Weinheim an Der Bergstrasse, Germany) 2017, 23 (59), 14712–14717. https://doi.org/10.1002/chem.201703309.
  33. Wang, H.; Zhou, F.; Ren, G.; Zheng, Q.; Chen, H.; Gao, B.; Klivansky, L.; Liu, Y.; Wu, B.; Xu, Q.; Lu, J.; Sharpless, K. B.; Wu, P. SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts. Angewandte Chemie (International Ed. in English) 2017, 56 (37), 11203–11208. https://doi.org/10.1002/anie.201701160.
  34. Hamadani, K. M.; Howe, J.; Jensen, M. K.; Wu, P.; Cate, J. H. D.; Marqusee, S. An in Vitro Tag-And-Modify Protein Sample Generation Method for Single-Molecule Fluorescence Resonance Energy Transfer. The Journal of Biological Chemistry 2017, 292 (38), 15636–15648. https://doi.org/10.1074/jbc.M117.791723.
  35. Ovryn, B.; Li, J.; Hong, S.; Wu, P. Visualizing Glycans on Single Cells and Tissues. Current Opinion in Chemical Biology 2017, 39, 39–45. https://doi.org/10.1016/j.cbpa.2017.04.018.
  36. Zha, G.-F.; Zheng, Q.; Leng, J.; Wu, P.; Qin, H.-L.; Sharpless, K. B. Palladium-Catalyzed Fluorosulfonylvinylation of Organic Iodides. Angewandte Chemie (International Ed. in English) 2017, 56 (17), 4849–4852. https://doi.org/10.1002/anie.201701162.
  37. Lopez Aguilar, A.; Briard, J. G.; Yang, L.; Ovryn, B.; Macauley, M. S.; Wu, P. Tools for Studying Glycans: Recent Advances in Chemoenzymatic Glycan Labeling. ACS Chemical Biology 2017, 12 (3), 611–621. https://doi.org/10.1021/acschembio.6b01089.
  38. Li, S.; Wu, P.; Moses, J. E.; Sharpless, K. B. Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched from an SOF4 Hub. Angewandte Chemie (International Ed. in English) 2017, 56 (11), 2903–2908. https://doi.org/10.1002/anie.201611048.
  39. Qin, H.-L.; Zheng, Q.; Bare, G. A. L.; Wu, P.; Sharpless, K. B. A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-Electrophiles for SuFEx Click Chemistry. Angewandte Chemie (International Ed. in English) 2016, 55 (45), 14155–14158. https://doi.org/10.1002/anie.201608807.
  40. Cook, I.; Wang, T.; Wang, W.; Kopp, F.; Wu, P.; Leyh, T. S. Controlling Sulfuryl-Transfer Biology. Cell Chemical Biology 2016, 23 (5), 579–586. https://doi.org/10.1016/j.chembiol.2016.04.009.
  41. Chen, W.; Dong, J.; Li, S.; Liu, Y.; Wang, Y.; Yoon, L.; Wu, P.; Sharpless, K. B.; Kelly, J. W. Synthesis of Sulfotyrosine-Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc-Based Solid-Phase Strategy. Angewandte Chemie (International Ed. in English) 2015, 55 (5), 1835–1838. https://doi.org/10.1002/anie.201509016.
  42. Zhang, E.; Tang, J.; Li, S.; Wu, P.; Moses, J. E.; Sharpless, K. B. Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates. Chemistry Europe 2016, 22 (16), 5692–5697. https://doi.org/10.1002/chem.201600167.
  43. Nordstrøm, L. U.; Sironi, J.; Aranda, E.; Maisonet, J.; Perez-Soler, R.; Wu, P.; Schwartz, E. L. Discovery of Autophagy Inhibitors with Antiproliferative Activity in Lung and Pancreatic Cancer Cells. ACS Medicinal Chemistry Letters 2015, 6 (2), 134–139. https://doi.org/10.1021/ml500348p.
  44. Jiang, H.; English, B. P.; Hazan, R. B.; Wu, P.; Ovryn, B. Tracking Surface Glycans on Live Cancer Cells with Single-Molecule Sensitivity. Angewandte Chemie (International Ed. in English) 2014, 54 (6), 1765–1769. https://doi.org/10.1002/anie.201407976.
  45. Rouhanifard, S. H.; López-Aguilar, A.; Wu, P. CHoMP: A Chemoenzymatic Histology Method Using Clickable Probes. ChemBioChem 2014, 15 (18), 2667–2673. https://doi.org/10.1002/cbic.201402433.
  46. Feng, L.; Jiang, H.; Wu, P.; Marlow, F. L. Negative Feedback Regulation of Wnt Signaling via N-Linked Fucosylation in Zebrafish. Developmental Biology 2014, 395 (2), 268–286. https://doi.org/10.1016/j.ydbio.2014.09.010.
  47. Yang, M.; Jalloh, A.; Wei, W. Zhao, J.*; Wu. P*; Chen, P.R.* Biocompatible Click Chemistry Enabled Labeling of Cytosolic Proteins and Compartment-specific pH Indicators. Nature Communications. 2014, 5 (4981), https://doi.org/10.1038/ncomms5981 (*co- corresponding authors). Highlighted in C&EN News: “Ligands Let Copper Click Inside Cells” 2014, 92 (39), 30.
  48. Jiang, H.; Zheng, T.; Lopez-Aguilar, A.; Feng, L.; Kopp, F.; Marlow, F. L.; Wu, P. Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chemistry 2014, 25 (4), 698–706. https://doi.org/10.1021/bc400502d.
  49. Bertozzi, C. R.; Wu, P. In Vivo Chemistry. Current Opinion in Chemical Biology 2013, 17, 717.
  50. Zheng, T.; Jiang, H.; Wu, P. Single-Stranded DNA as a Cleavable Linker for Bioorthogonal Click Chemistry-Based Proteomics. Bioconjugate Chemistry 2013, 24 (6), 859–864. https://doi.org/10.1021/bc400093x.
  51. Rouhanifard, S. H.; Nordstrøm, L. U.; Zheng, T.; Wu, P. Chemical Probing of Glycans in Cells and Organisms. Chemical Society Reviews 2013, 42 (10), 4284–4296. https://doi.org/10.1039/c2cs35416k.
  52. Rouhanifard, S. H.; Xie, R.; Zhang, G.; Sun, X.; Chen, X.; Wu, P. Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles. Biomacromolecules 2012, 13 (10), 3039–3045. https://doi.org/10.1021/bm3007506.
  53. Zheng, T.; Rouhanifard S.H.; Jalloh A. S.; Wu P. Top. Click Triazoles for Bioconjugation. Journal of Heterocyclic Chemistry 2012, 28, 163.
  54. Lakshmanan, V.; Rhee, K. Y.; Wang, W.; Yu, Y.; Khafizov, K.; Fiser, A.; Wu, P.; Ndir, O.; Mboup, S.; Ndiaye, D.; Daily, J. P. Metabolomic Analysis of Patient Plasma Yields Evidence of Plant-like α-Linolenic Acid Metabolism in Plasmodium Falciparum. The Journal of Infectious Diseases 2012, 206 (2), 238–248. https://doi.org/10.1093/infdis/jis339.
  55. Li, B.; Mock, F.; Wu, P. Imaging the Glycome in Living Systems. Methods in Enzymology 2012, 401–419. https://doi.org/10.1016/b978-0-12-388448-0.00029-2.
  56. Wang, W.; Hong, S.; Tran, A.; Jiang, H.; Triano, R.; Liu, Y.; Chen, X.; Wu, P. Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition. Chemistry, an Asian Journal 2011, 6 (10), 2796–2802. https://doi.org/10.1002/asia.201100385.
  57. Besanceney-Webler, C.; Jiang, H.; Wang, W.; Baughn, A. D.; Wu, P. Metabolic Labeling of Fucosylated Glycoproteins in Bacteroidales Species. Bioorganic & Medicinal Chemistry Letters 2011, 21 (17), 4989–4992. https://doi.org/10.1016/j.bmcl.2011.05.038.
  58. Jiang, H.; Feng, L.; Soriano del Amo, D.; Seidel III, R. D.; Marlow, F.; Wu, P. Imaging Glycans in Zebrafish Embryos by Metabolic Labeling and Bioorthogonal Click Chemistry. Journal of Visualized Experiments 2011, 52. https://doi.org/10.3791/2686.
  59. Besanceney-Webler, C.; Jiang, H.; Zheng, T.; Feng, L.; Soriano del Amo, D.; Wang, W.; Klivansky, L. M.; Marlow, F. L.; Liu, Y.; Wu, P. Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study. Angewandte Chemie (International Ed. in English) 2011, 50 (35), 8051–8056. https://doi.org/10.1002/anie.201101817.
  60. Dehnert, K. W.; Beahm, B. J.; Huynh, T. T.; Baskin, J. M.; Laughlin, S. T.; Wang, W.; Wu, P.; Amacher, S. L.; Bertozzi, C. R. Metabolic Labeling of Fucosylated Glycans in Developing Zebrafish. ACS Chemical Biology 2011, 6 (6), 547–552. https://doi.org/10.1021/cb100284d.
    LacNAc-Angew
  61. Zheng, T.; Jiang, H.; Gros, M.; del Amo, D. S.; Sundaram, S.; Lauvau, G.; Marlow, F.; Liu, Y.; Stanley, P.; Wu, P. Tracking N-Acetyllactosamine on Cell-Surface Glycans in Vivo. Angewandte Chemie (International Ed. in English) 2011, 50 (18), 4113–4118. https://doi.org/10.1002/anie.201100265.
    Fucosylation-JACS
  62. Soriano Del Amo, D.; Wang, W.; Jiang, H.; Besanceney, C.; Yan, A. C.; Levy, M.; Liu, Y.; Marlow, F. L.; Wu, P. Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans. Journal of the American Chemical Society 2010, 132 (47), 16893–16899. https://doi.org/10.1021/ja106553e.
  63. Soriano del Amo, D.; Wang, W.; Besanceney, C.; Zheng, T.; He, Y.; Gerwe, B.; Seidel, R. D.; Wu, P. Chemoenzymatic Synthesis of the Sialyl Lewis X Glycan and Its Derivatives. Carbohydrate Research 2010, 345 (9), 1107–1113. https://doi.org/10.1016/j.carres.2010.03.032.
  64. Breidenbach, M. A.; Gallagher, J. E. G.; King, D. S.; Smart, B. P.; Wu, P.; Bertozzi, C. R. Targeted Metabolic Labeling of Yeast N-Glycans with Unnatural Sugars. Proceedings of the National Academy of Sciences 2010, 107 (9), 3988–3993. https://doi.org/10.1073/pnas.0911247107.
  65. Yap, M. C.; Kostiuk, M. A.; Martin, D. D. O.; Perinpanayagam, M. A.; Hak, P. G.; Siddam, A.; Majjigapu, J. R.; Rajaiah, G.; Keller, B. O.; Prescher, J. A.; Wu, P.; Bertozzi, C. R.; Falck, J. R.; Berthiaume, L. G. Rapid and Selective Detection of Fatty Acylated Proteins Using Omega-Alkynyl-Fatty Acids and Click Chemistry. Journal of Lipid Research 2010, 51 (6), 1566–1580. https://doi.org/10.1194/jlr.D002790.
  66. Wang, W.; Hu, T.; Frantom, P. A.; Zheng, T.; Gerwe, B.; del Amo, D. S.; Garret, S.; Seidel, R. D.; Wu, P. Chemoenzymatic Synthesis of GDP- L -Fucose and the Lewis X Glycan Derivatives. Proceedings of the National Academy of Sciences 2009, 106 (38), 16096–16101. https://doi.org/10.1073/pnas.0908248106.
  67. Chang, P. V.; Chen, X.; Smyrniotis, C.; Xenakis, A.; Hu, T.; Bertozzi, C. R.; Wu, P. Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars. Angewandte Chemie (International Ed. in English) 2009, 48 (22), 4030–4033. https://doi.org/10.1002/anie.200806319.
  68. Perrine, C. L.; Ganguli, A.; Wu, P.; Bertozzi, C. R.; Fritz, T. A.; Raman, J.; Tabak, L. A.; Gerken, T. A. Glycopeptide-Preferring Polypeptide GalNAc Transferase 10 (PpGalNAc T10), Involved in Mucin-Type O-Glycosylation, Has a Unique GalNAc-O-Ser/Thr-Binding Site in Its Catalytic Domain Not Found in PpGalNAc T1 or T2. Journal of Biological Chemistry 2009, 284 (30), 20387–20397. https://doi.org/10.1074/jbc.m109.017236.
  69. Wu, P.; Shui, W.; Carlson, B. L.; Hu, N.; Rabuka, D.; Lee, J.; Bertozzi, C. R. Site-Specific Chemical Modification of Recombinant Proteins Produced in Mammalian Cells by Using the Genetically Encoded Aldehyde Tag. Proceedings of the National Academy of Sciences 2009, 106 (9), 3000–3005. https://doi.org/10.1073/pnas.0807820106.
  70. Chen, X.; Wu, P.; Rousseas, M.; Okawa, D.; Gartner, Z.; Zettl, A.; Bertozzi, C. R. Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells. Journal of the American Chemical Society 2009, 131 (3), 890–891. https://doi.org/10.1021/ja807334b.
  71. Wu, P.; Chen, X.; Hu, N.; Tam, U.; Blixt, O.; Zettl, A.; Bertozzi, Carolyn R. Biocompatible Carbon Nanotubes Generated by Functionalization with Glycodendrimers. Angewandte Chemie (International Ed. in English) 2008, 47 (27), 5022–5025. https://doi.org/10.1002/anie.200705363.
  72. Vestberg, R.; Malkoch, M.; Kade, M.; Wu, P.; Fokin, V. V.; Barry Sharpless, K.; Drockenmuller, E.; Hawker, C. J. Role of Architecture and Molecular Weight in the Formation of Tailor-Made Ultrathin Multilayers Using Dendritic Macromolecules and Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry 2007, 45 (14), 2835–2846. https://doi.org/10.1002/pola.22178.
  73. Wu, P.; Fokin, V. Catalytic Dipolar Cycloaddition of Azides and Alkynes: Reactivity and Applications. Aldrichimica Acta 2007, 40, 7.
  74. Wu, P.; Hilgraf, R.; Fokin, Valery V. Osmium-Catalyzed Olefin Dihydroxylation and Aminohydroxylation in the Second Catalytic Cycle. Advanced Synthesis & Catalysis 2006, 348 (9), 1079–1085. https://doi.org/10.1002/adsc.200505252.
  75. Fokin, V. V.; Wu, P. Epoxides and Aziridines in Click Chemistry. Aziridines and Epoxides in Organic Synthesis 2006, 443–477. https://doi.org/10.1002/3527607862.ch12.
  76. Wu, P.; Malkoch, M.; Hunt, J. N.; Vestberg, R.; Kaltgrad, E.; Finn, M. G.; Fokin, V. V.; Sharpless, K. B.; Hawker, C. J. Multivalent, Bifunctional Dendrimers Prepared by Click Chemistry. Chemical Communications 2005, 46, 5775. https://doi.org/10.1039/b512021g.
  77. Sharpless, W. D.; Wu, P.; Hansen, T.; Lindberg, J. G. Just Click It: Undergraduate Procedures for the Copper(I)-Catalyzed Formation of 1,2,3-Triazoles from Azides and Terminal Acetylenes. Journal of Chemical Education 2005, 82, 1833.
  78. Hansen, T. V.; Wu, P.; Fokin, V. V. One-Pot Copper(I)-Catalyzed Synthesis of 3,5-Disubstituted Isoxazoles. The Journal of Organic Chemistry 2005, 70 (19), 7761–7764. https://doi.org/10.1021/jo050163b.
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