The Scripps Research Institute - At The Forefront
March 2014 Connect with us:
Focus on:
A Test That Could Predict Heart Attacks

One in three people who have a heart attack die before reaching the hospital. However, it's hard to know your risk of having an attack – even moments before one occurs.

At The Scripps Research Institute (TSRI), a team led by Associate Professor Peter Kuhn has developed a new test that could identify patients who are at high risk of having a heart attack in the upcoming days or weeks. They could then be given a potentially life-saving treatment to prevent the heart attack from occurring.

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Peter Kuhn
TSRI Associate Professor Peter Kuhn
Our research is breaking new ground in detecting and treating life-threatening conditions like heart disease and Alzheimer's that affect millions of people around the world. Help us continue working towards better treatments and cures. donate now
Marisa Roberto
TSRI Associate Professor Marisa Roberto
milestones in medical science:
Nature's Balm for a Stressed Brain

Stress-related conditions are common in modern societies, including post-traumatic stress disorder and the drug-withdrawal stress that often defeats addicts' efforts to kick their habit.

Collaborating scientists at TSRI, the National Institutes of Health (NIH), and the University of Camerino in Italy have identified a system in the brain that naturally moderates the effects of stress and helps the brain return to "normal." The findings confirm the importance of this stress-damping system – known as the nociceptin system – as a potential target for therapies against anxiety disorders and other stress-related conditions.

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Srini Subramaniam
TSRI Assistant Professor Srini Subramaniam
Other News:
A Protein that Could Slow Alzheimer's Progression

Scientists from Scripps Florida, led by TSRI biologist Srini Subramaniam, have identified a protein that is a critical regulator of a molecule deeply involved in the progression of Alzheimer's disease. The study shows, for the first time, that levels of this regulating protein (known as Rheb) are lower in the brains of Alzheimer's disease sufferers and that this decrease could be a significant factor in the advance of the disease.

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TSRI Chemist Chi-Huey Wong Wins Prestigious Wolf Prize

Professor Chi-Huey Wong has won the 2014 Wolf Prize in Chemistry for pioneering methods to synthesize complex carbohydrates, glycoproteins and other related substances critical to biology and medicine that had previously proved impossible or unfeasible to synthesize. Sometimes cited as the most prestigious award after the Nobel Prize, the Wolf Prize is presented to living scientists and artists for "achievements in the interest of mankind and friendly relations among peoples" by the Israel-based Wolf Foundation. Congratulations, Dr. Wong!
facts & figures

Heart disease is the leading cause of death for both men and women in the U.S. and is responsible for approximately 1 out of 4 deaths in the country each year.
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