January 2013

The Scripps Research Institute

At the Forefront


Dear Scripps Research Institute Friend,

As we embark on a new year with many promising projects ahead, we want to thank you for your support in 2012. Thanks to you, we made great strides in several fields of biomedical research, and we are optimistic that we will continue to do so this year.

Your commitment to our research is integral to finding the treatments and cures of tomorrow. We look forward to sharing future successes with you for years to come.

With gratitude,


William J. Burfitt
Director, Office of Philanthropy


Focus On:

http://contenta.mkt5124.com/ra/2013/36766/01/5441833/i_2013_01_taffe_miller.jpgAssociate Professor Michael Taffe and Research Associate Michelle Miller

Meth vaccine shows promise

How much incentive would a drug user have to keep using if he or she weren't able to get high? Not much, according to TSRI scientists who have been working to develop a vaccine that would prevent a high for methamphetamine addicts.

A methamphetamine vaccine could offer a critical new tool in loosening the drug's grip on an estimated 25 million people around the world. There is no approved treatment for meth addiction, and in addition to being one of the most widely used recreational drugs, it is also more addictive than many other commonly abused drugs.



Milestones in Medical Science:

TSRI Professor Donald G. PhinneyProfessor Donald G. Phinney

Scripps Florida scientists uncover a novel cooperative effort to stop cancer spread

New research from TSRI has uncovered a handful of potential therapeutic targets to slow or stop the spread of cancer. These targets could also lead the way to new diagnostic tools to predict metastasis.

The research from Scripps Florida Professor Donald Phinney is centered around a group of regulators in the body that were previously considered relatively minor. Dr. Phinney and his team, however, found that these regulators can act together to stop the spread of cancer from its primary site.



Other News:

TSRI ResearchersAuthors of the new paper include Professor Ulrich Mueller (back), Senior Research Associates Nicolas Grillet (left) and Wei Xiong.

Researchers identify molecules in the ear that convert sound into brain signals

Some people go deaf from overexposure to loud noise, while others lose their hearing as they age. But roughly half of children born deaf in the U.S. have genetic causes to blame, according to the Centers for Disease Control and Prevention.

Now, TSRI investigators have discovered a protein behind one form of genetic deafness. The finding could open a new avenue for potentially using gene therapy to give hearing to those who were born without it.


Facts & Figures

Fossilized remains from dinosaurs that died 120 million years ago have been found with structures nearly identical to the modern human inner ear.

The value of basic research

Many of history's most important discoveries were made not in pursuit of a narrow goal, but in pursuit of a broader understanding. TSRI focuses top talent and cutting-edge technology on building the basic scientific knowledge that will bring tomorrow's treatments and cures. Help us.

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The IRA charitable rollover is here again for 2012 and 2013

Donors age 70 � or older are once again eligible to move up to $100,000 from their IRAs directly to qualified charities without having to pay income taxes on the money. To qualify for 2012 contributions, you must act by January 31st! To learn more about this opportunity, visit our Planned Giving site or contact Geoff C. Graham, director, Planned Giving and Estates at (858) 784-9365.

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email: philanthropy@scripps.edu - www.supportcures.org