Vol 9. Issue 17 / May 18, 2009

The Graduating Students

The 41 individuals who are graduating from The Scripps Research Institute's Kellogg School of Science and Technology this week are listed below, with the names of their advisors and thesis titles.

Astronomo, Rena D.

Hitting the Sweet Spot on HIV: Immunological Perspectives on Synthetic Carbohydrate Vaccine Strategies

Advisor: Dennis Burton, Professor, Department of Immunology and Microbial Science


Beierle, John M.

Peptide Derivatives in New Modes of Molecular Recognition

Advisor: Reza Ghadiri, Professor, Department of Chemistry


Brenzovich, William E. Jr.

Progress Towards the Total Synthesis and Structural Assignment of Amphidinolide N and Caribenolide I

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry


Brustad, Eric M.

Applications of an Expanded Genetic Code

Advisor: Peter Schultz, Professor, Department of Chemistry


Chappie, Joshua

Defining the Mechanisms and Regulation of Dynamin's GTPase Activities

Co-Advisors:
Ronald Milligan, Associate Professor, Department of Cell Biology
Sandra Schmid, Professor and Chair, Department of Cell Biology


Chen, Jason Shih-Hao

Part I. Chemistry and Biology of Uncialamycin
Part II. Total Synthesis of Aspidophytine

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry


Clark, Julie Hsu

Synthetic and Endogenous Small Molecules that Regulate Stem Cell Fate

Advisor: Sheng Ding, Associate Professor, Department of Chemistry


Clark, Ryan C.

I. An Asymmetric Variant of the 1-Azadiene Diels-Alder Reaction,
II total Synthesis, Sterochemical Reassignment and Absolute Configuration of Chlorofusin

Advisor: Dale Boger, Professor, Department of Chemistry


Dale, Trevor James

Photophysical Probes for Nerve Agent Sensing and the Study of Molecular Encapsulation

Advisor: Julius Rebek, Jr., Professor and Director, The Skaggs Institute for Chemical Biology


DeMartino, Jessica K.

Synthesis and Evaluation of Inhibitors of Glycinamide Ribonucleotide Transformylase and Fatty Acid Amide Hydrolase

Advisor: Dale Boger, Professor, Department of Chemistry


DeMartino, Michael P.

The Design and Development of Oxidative Enolate Heterocoupling and Application Toward the Total Synthesis of the Taiwankadsurins

Advisor: Phil Baran, Professor, Department of Chemistry


Frederick, Michael Oliver

Synthesis of Polyether Natural Products:
Part 1. Total Synthesis of Azaspiracids-1 and -2,
Part 2. Synthesis of the G-O Domain of Maitotoxin

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry


Giri, Ramesh

Chelation-Assisted Palladium-Catalyzed Activation of C-H Bonds: A New Avenue for Carbon-Heteroatom and Carbon-Carbon Bond Formation

Advisor: Jinquan Yu, Professor, Department of Chemistry


Gordley, Russell Morrison

Programmable Zinc Finger-Recombinases for Targeted Genome Editing

Advisor: Carlos Barbas III, Professor, Department of Chemistry


Guerrero, Carlos Ariel

Enantiospecific Syntheses of Stephacidin and Cortistatin Alkaloids

Advisor: Phil Baran, Professor, Department of Chemistry


Hafensteiner, Benjamin D.

Enantioselective Total Synthesis of Stephacidin A, Stephaciden B, Avrainvillamide and a Related Biological Probe

Advisor: Phil Baran, Professor, Department of Chemistry


Hills, Ronald D. Jr.

Protein Folding and Aggregation Dynamics

Advisor: Charles Brooks, III


Hur, Wooyoung

I. A Small Molecule Inducer of the Antioxidant Response Element,
II. Design and Characterization of Irreversible Kinase Inhibitors

Advisor: Peter Schultz, Professor, Department of Chemistry


Jeso, Valer

Synthetic Studies Toward Polycyclic Polyprenylated Acylphloroglucinols

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry


Kazmierczak, Piotr

Molecules of Mechanotransduction. Cadherin 23 and Protocadherin 15 Interact to form Tip-link Filaments.

Advisor: Ulrich Mueller, Professor, Department of Cell Biology


Komori, Heather Kiyomi

Application of a Soluble Vγ3Vδ1 T Cell Receptor Towards Understanding Dendritic Epidermal T Cell Activation

Advisor: Wendy Havran, Professor, Department of Immunology and Microbial Science


Koudelka, Kristopher J.

Elucidation of Mammalian Binding and Entry of Cowpea Mosaic Virus Via Surface Vimentin; Implications for Nanotechnology and Virus Evolution

Advisor: Marianne Manchester, Professor, Department of Cell Biology


Lander, Gabe

Structural Architecture of Bacteriophage Described via Streamlined Cryo-Electron Microscopy

Co-Advisors:
Bridget Carragher, Associate Professor, Department of Cell Biology
John Johnson, Professor, Department of Molecular Biology


Lee, Joon Youb

Factors Regulating T-Cell Proliferation in Chronically Immunodeficient Hosts

Advisor: Charles Surh, Professor, Department of Immunology and Microbial Science


Lee, Sang Yeul

Chlorofusin: Total Synthesis, Stereochemical Reassignment, Determination of Absolute Configuration, and the Synthesis of Seven Chromophore Analogs

Advisor: Dale Boger, Professor, Department of Chemistry


Lincoln, Tracey

Self-Sustained Replication of an RNA Enzyme

Advisor: Gerald Joyce, Professor, Department of Department of Molecular Biology and Chemistry


Marrinucci, Dena Christine

The Clinical and Biological Significance of Circulating Tumor Cells

Advisor:
Peter Kuhn, Associate Professor, Department of Cell Biology


Michino, Mayako

Structure Prediction of Class A GPCRs

Co-Advisors:
Charles L. Brooks III
Raymond Stevens, Professor, Department of Molecular Biology


Niessen, Sherry L.

Characterization of a Role for the Serine Hydrolase Enzyme KIAA1363 in Cancer Biology Using Functional Proteomics and Metabolomics

Advisor: Benjamin Cravatt, Professor and Chair, Department of Chemical Physiology


Pragani, Rajan

Studies Toward the Synthesis of Durhamycins A and B and Ziracin

Advisor:
William Roush, Professor, Department of Chemistry


Pratt, Benjamin Anthony

The Design and Synthesis of Highly Potent Epothilone B Analogues and Progress Toward the Total Synthesis of Sinularia Natural Products

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry


Radakovits, Randor R.

Investigating the role of β1 integrins and glial fibers in the survival of radial glial cells

Advisor: Ulrich Mueller, Professor, Department of Cell Biology


Raushel, Jessica

Part I. Sulfonyl Azides: Copper-Mediated Synthesis and Applications
Part II. Acetylcholinesterase in Situ Clock Chemistry Screening

Advisor:
K. Barry Sharpless, Professor, Department of Chemistry


Scherer, Erin M.

Antibody Recognition of a Protein Epitope Close to a Membrane: A Novel Solution

Advisor: Dennis Burton, Professor, Department of Immunology and Microbial Science


Schnermann, Martin John

I. Total Synthesis of Piericidin A1 and B1 and Key Analogues,
II. Studies Towards the Total Synthesis of Vinblastine and Velbanamine Aryl Analogues

Advisor: Dale Boger, Professor, Department of Chemistry


Shenvi, Ryan A.

Pure and Applied Science in the Chemical Synthesis of Marine Alkaloids Chartelline C and Cortistatin A

Advisor: Phil Baran, Professor, Department of Chemistry


Siegel, Sarah J.

Structure and Energetics of Amyloid

Advisor: Jeffrey Kelly, Professor and Chair, Department of Molecular and Experimental Medicine


Slown, Corin D.

Studies Toward Understanding the Mechanism of Bleomycin: Total Synthesis of 15N-labeled Bleomycin

Advisor: Dale Boger, Professor, Department of Chemistry


Thielges, Megan C.

Novel Approaches to the Study of Protein Dynamics

Advisor:
Floyd Romesberg, Associate Professor, Department of Chemistry


Voytek, Sarah B.

Continuous In Vitro Evolution of Competing Ligase Ribozymes

Advisor: Gerald Joyce, Professor, Department of Department of Molecular Biology and Chemistry


Yonemoto, Isaac

Theory, Methods and Investigations in Amyloid Dynamics

Advisor: Jeffrey Kelly, Professor and Chair, Department of Molecular and Experimental Medicine


 
     

 

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