Lamia KA. Ticking time bombs: connections between circadian clocks and cancer.

F1000Res. 2017 Oct 30

Henriksson E, Huber AL, Soto EK, Kriebs A, Vaughan ME, Duglan D, Chan AB, Papp SJ, Nguyen M, Afetian ME, Lamia KA. The liver circadian clock modulates biochemical and physiological responses to metformin. J Biol Rhythms. 2017 Aug

Kriebs A, Jordan SD, Soto E, Henriksson E, Sandate CR, Vaughan ME, Chan AB, Duglan D, Papp SJ, Huber AL, Afetian ME, Yu RT, Zhao X, Downes M, Evans RM, Lamia KA. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proc Natl Acad Sci U S A. 2017 Aug 15

Jordan SD, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, Huber AL, Papp SJ, Nguyen M, Afetian M, Downes M, Yu RT, Kralli A, Evans RM, Lamia KA. CRY1/2 selectively repress PPARd and limit exercise capacity. Cell Metab. 2017 Jul 5

Huber AL, Papp SJ, Chan AB, Henriksson E, Jordan SD, Kriebs A, Nguyen M, Wallace M, Li Z, Metallo CM and Lamia KA. CRY2 and FBXL3 Cooperatively Degrade c-MYC. Mol Cell 2016 Nov 17.

Zhao X, Hirota T, Han X, Cho H, Chong LW, Lamia K, Liu S, Atkins AR, Banayo E, Liddle C, Yu RT, Yates JR 3rd, Kay SA, Downes M, and Evans RM. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell 2016 Jun 16.

Henriksson E and Lamia KA. Adipose clocks: Burning the Midnight Oil. J Biol Rhythms 2015 Apr 29.

Papp SJ, Huber AL, Jordan SD, Kriebs A, Nguyen M, Moresco J, Yates III J, and Lamia KA. DNA damage shifts circadian clock time via Hausp-mediated Cry1 stabilization. ELife. 2015 Mar 10.

Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors. Cell. 2013 Nov 7.

Jordan SD and Lamia KA.  AMPK at the Crossroads of Circadian Clocks and Metabolism.  Mol Cell Endocrinol. 2012 Jun 28

Lamia KA, Papp SJ, Yu RT, Barish GB, Uhlenhaut NH, Jonker JW, Downes M and Evans RM.  Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.  Nature 2011 Dec 14; 480(7378):552-6

*Faculty of 1000: .

Sadacca LA*, Lamia KA*, Delemos AS, Blum B and Weitz CJ.  An Intrinsic Circadian Clock of the Pancreas is Required for Normal Insulin Release and Glucose Homeostasis in Mice.  Diabetologia 2011 Jan;54(1):120-4.

Lamia KA and Evans RM.  Tick, tock, a beta cell clock.  Nature 2010 Jul 29; 466(7306):571-2.

Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB and Evans RM.  AMPK Regulates Circadian Clocks by Phosphorylation and Degradation of Cryptochromes.  Science 2009 Oct 16; 326(5951):437-40.

Lamia KA, Storch KF and Weitz CJ.  Physiological Importance of a Peripheral Tissue Circadian Clock. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):15172-7.

*Faculty of 1000: .

Yang X, Lamia KA and Evans RM.  Nuclear Receptors, Metabolism and the Circadian Clock Cold Spring Harb Symp Quant Biol.  2007;72:387-94.  Review.

Shaw RJ, Lamia KA, Vasquez D, Koo S-H, Bardeesy N, DePinho RA, Montminy M, and Cantley LC.  The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin.  Science. 2005 Dec 9;310(5754):1642-6.

Lamia KA, Peroni OM, Kim YB, Rameh LE, Kahn BB, and Cantley LC. Increased Insulin Sensitivity and Reduced Adiposity in PI5P4Kb-/- Mice Mol Cell Biol. 2004 Jun; 24(11):5080-7.

Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, and Rameh LE. The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9867-72.

Field SJ, Lamia KA, Rameh LE, Cantley LC. Lipid research picks up speed on the slopes of Taos. Dev Cell 2002 Apr;2(4):407-10.