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Welcome to the Havran Lab

We have a long-term interest in interactions between intraepithelial γδ T cells and their neighboring epithelial cells. We focus on interactions in the thymus, skin, and intestine. We are investigating the development, specificity, and function of these γδ T cells. Our results have defined unique properties of these cells and support a specialized role for intraepithelial γδ T cells in immune surveillance, wound repair, inflammation, and protection from malignant tumors

Epidermal sheet showing keratinocytes, langerhans cells, and T cells

Epidermal ear sheet showing the interactions of γδ T cells (green), Langerhans cells (red) and keratinocytes (blue)