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X-Ray Crystallography Core Facility

Long Term Collaborative Projects

-Inhibitor Design and Optimization of Protein Kinases
-RNA Repeat Expansion Disease
Rna crystal Crystals obtained from RNA constructs containing sequences of RNA repeat expansion disease.
 -Receptor forAdvance Glycation Endproduct
Rage Surface features of RAGE structure; Mixed hydrophobic and positively charged regions make up multiple ligand binding sites.
 -Natural Product Inspired Synthesis
CrystalHSP90 Crystal structure of Hsp90 in complex with a geldanamycin-like compound. The 2Fo-Fc electron density map of the bound compound is shown in three contour levels.