Mark Sundrud

Department of Immunology and Microbiology
Florida Campus


Scripps Research Joint Appointments

Department of Immunology and Microbial Science
Faculty, Graduate Program

Research Focus


Ph.D. (Microbiology and Immunology), Vanderbilt University Medical Center, 2005
B.S. (Biology and Psychology), Concordia College (Moorhead, Minnesota), 2000

Professional Experience

2017-2018 Assistant Professor, Immunology and Microbiology, Scripps Research
2017-2018 Assistant Professor (Joint Appointment), Molecular Medicine, Scripps Research
2013-2017 Assistant Professor, Cancer Biology, Scripps Research

Awards & Professional Activities

Selected References

All Publications

Chen, M. L., Huang, X. S., Wang, H. T., Hegner, C., Liu, Y. J., Shang, J. S., Eliason, A., Diao, H., Park, H., Frey, B., Wang, G. H., Mosure, S. A., et al. CAR directs T cell adaptation to bile acids in the small intestine. (2021). Nature, 593(7857), 147-151.

Basson, A. R., Chen, C., Sagl, F., Trotter, A., Bederman, I., Gomez-Nguyen, A., Sundrud, M. S., Ilic, S., Cominelli, F. & Rodriguez-Palacios, A. Regulation of Intestinal Inflammation by Dietary Fats. (2021). Frontiers in Immunology, 11. PMCID: PMC7884479.

Chen, M. L., Sun, A., Cao, W., Eliason, A., Mendez, K. M., Getzler, A. J., Tsuda, S., Diao, H., Mukori, C., Bruno, N. E., Kim, S. Y., Pipkin, M. E., et al. Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes. (2020). Journal of Experimental Medicine, 217. PMCID: PMC7201929.

Kim, Y., Sundrud, M. S., Zhou, C., Edenius, M., Zocco, D., Powers, K., Zhang, M., Mazitschek, R., Rao, A., Yeo, C. Y., Noss, E. H., Brenner, M. B., et al. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. (2020). Proceedings of the National Academy of Sciences of the United States of America, 117(16), 8900-8911. PMCID: PMC7183223.

Basson, A. R., LaSalla, A., Lam, G., Kulpins, D., Moen, E. L., Sundrud, M. S., Miyoshi, J., Ilic, S., Theriault, B. R., Cominelli, F. & Rodriguez-Palacios, A. Artificial microbiome heterogeneity spurs six practical action themes and examples to increase study power-driven reproducibility. (2020). Scientific Reports, 10. PMCID: PMC7081340.

Chen, M. L., Takeda, K. & Sundrud, M. S. Emerging roles of bile acids in mucosal immunity and inflammation. (2019). Mucosal Immunology, 12(4), 851-861.

Sundrud, M. S. & Hogan, S. P. What's old is new again: Batf transcription factors and Th9 cells. (2019). Mucosal Immunology, 12(3), 583-585.

Chen, M. L. & Sundrud, M. S. Xenobiotic and endobiotic handling by the mucosal immune system. (2018). Current Opinion in Gastroenterology, 34(6), 404-412.

Fanok, M. H., Sun, A., Fogli, L. K., Narendran, V., Eckstein, M., Kannan, K., Dolgalev, I., Lazaris, C., Heguy, A., Laird, M. E., Sundrud, M. S., Liu, C., et al. Role of dysregulated cytokine signaling and bacterial triggers in the pathogenesis of cutaneous T-cell lymphoma. (2018). Journal of Investigative Dermatology, 138(5), 1116-1125. PMCID: PMC5912980.

Cao, W., Kayama, H., Chen, M. L., Delmas, A., Sun, A., Kim, S. Y., Rangarajan, E. S., McKevitt, K., Beck, A. P., Jackson, C. B., Crynen, G., Oikonomopoulos, A., et al. The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids. (2017). Immunity, 47(6), 1182-1196. PMCID: PMC5741099.