Junli Luo, PhD

Associate Professor
Department of Molecular Medicine
Florida Campus


Scripps Research Joint Appointments

Associate Professor, Department of Cancer Biology
Faculty, Graduate Program

Research Focus

The research in Luo's lab focuses on mechanistic and translational research in molecular signaling that connects epigenetic factors with genetic events during tumor genesis, progression and metastasis. Specifically, Luo's lab is working on how epigenetic signaling regulates cancer initial cells self-renewal and trans-differentiation.

Education

Ph.D. (Oncology and Cancer Biology), Hunan Medical University, 1997
M.D. (Clinical Medical Science), Hunan Medical University, 1989
Hunan Medical University, Department of Head and Neck Cancer, 1997

Professional Experience

2014-2017 Associate Professor, Cancer Biology, Scripps Research
2008-2014 Assistant Professor, Cancer Biology, Scripps Research
2002-2008 Postdoctoral Fellow with Dr. Michael Karin, School of Medicine, University of California, San Diego
1999-2002 Visiting Scientist with Dr. Monica Hollstein and Dr. Zhao-Qi Wang, German Cancer Research Center
1998-1999 Doctor in Charge / Lecturer, Department of Head and Neck Cancer, Hunan Medical University
1997-1998 IARC Fellow with Dr. Monica Hollstein, German Cancer Research Center

Selected References

All Publications

Wang, G. G., Song, J., Wang, Z., Dormann, H. L., Casadio, F., Li, H., Luo, J-L., Patel, D. J., and Allis, C. D. 2009. Haematopoietic malignancies initiated by dysregulation of a chromatin-binding PHD finger. Nature, May 19.

Kim, S., Takahashi, H., Lin, W-W., Descargues, P., Grivennikov, S., Kim Y., Luo, J-L., Karin M. 2009. Carcinoma Produced Factors Activate Myeloid Cells via TLR2 to Stimulate Metastasis.Nature, 457:102-6.

Matsuzawa, A., Tseng, P-H., Vallabhapurapu, S., Luo, J-L., Zhang, W., Wang, H., Vignali, D. A. A., Gallagher, E., Karin, M. (2008) Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.Science, 321:663-8.

Luo, J-L., Tan, W., Ricono, J. M., Korchynskyi, O., Zhang, M., Gonias, S. L., Cheresh D. A., and Karin, M. (2007) Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature, 446: 690-4.