Michalina Janiszewska, PhD

Assistant Professor
Department of Molecular Medicine
Florida Campus


 Email

Scripps Research Joint Appointments

Faculty, Graduate Program

Education

Ph.D. (Oncology and Cancer Biology), University of Lausanne, 2012
M.S. (Medical Biotechnology), University of Wroclaw, 2007
B.S. (Biotechnology), University of Wroclaw, 2005

Professional Experience

2016-2018 Instructor of Medicine, Dana-Farber/Harvard Cancer Center
2012-2016 Postdoctoral Research Fellow, Dana-Farber/Harvard Cancer Center
2012-2012 Postdoctoral Research Fellow, CHUV- Lausanne University Hospital

Selected References

All Publications

Hoxha, S., Shepard, A., Troutman, S., Diao, H., Doherty, J. R., Janiszewska, M., Witwicki, R. M., Pipkin, M. E., Ja, W. W., Kareta, M. S. & Kissil, J. L. YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. (2020). Cancer Research, 80(12), 2512-2522. PMCID: PMC7299785.

Marusyk, A., Janiszewska, M. & Polyak, K. Intratumor heterogeneity: The Rosetta Stone of therapy resistance. (2020). Cancer Cell, 37(4), 471-484. PMCID: PMC7181408.

Janiszewska, M. The microcosmos of intratumor heterogeneity: The space-time of cancer evolution. (2020). Oncogene, 39(10), 2031-2039.

Janiszewska, M., Tabassum, D. P., Castano, Z., Cristea, S., Yamamoto, K. N., Kingston, N. L., Murphy, K. C., Shu, S., Harper, N. W., Del Alcazar, C. G., Aleckovic, M., Ekram, M. B., et al. Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments. (2019). Nature Cell Biology, 21(7), 879-+. PMCID: PMC6609451.

Janiszewska, M. & Polyak, K. A confetti trail of tumour evolution. (2018). Nature Cell Biology, 20(6), 639-641.

Maley, C. C., Aktipis, A., Graham, T. A., Sottoriva, A., Boddy, A. M., Janiszewska, M., Silva, A. S., Gerlinger, M., Yuan, Y., Pienta, K. J., Anderson, K. S., Gatenby, R., et al. Classifying the evolutionary and ecological features of neoplasms. (2017). Nature Reviews Cancer, 17(10), 605-619. PMCID: PMC5811185.

Degrauwe, N., Suva, M. L., Janiszewska, M., Riggi, N. & Stamenkovic, I. IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer. (2016). Genes & Development, 30(22), 2459-2474. PMCID: PMC5159662.

Marusyk, A., Tabassum, D. P., Janiszewska, M., Place, A. E., Trinh, A., Rozhok, A. I., Pyne, S., Guerriero, J. L., Shu, S., Ekram, M., Ishkin, A., Cahill, D. P., et al. Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes. (2016). Cancer Research, 76(22), 6495-6506. PMCID: PMC5344673.

Degrauwe, N., Schlumpf, T. B., Janiszewska, M., Martin, P., Cauderay, A., Provero, P., Riggi, N., Suva, M. L., Paro, R. & Stamenkovic, I. The RNA binding protein IMP2 preserves glioblastoma stem cells by preventing let-7 target gene silencing. (2016). Cell Reports, 15(8), 1634-1647.

Shu, S., Lin, C. Y., He, H. H., Witwicki, R. M., Tabassum, D. P., Roberts, J. M., Janiszewska, M., Huh, S. J., Liang, Y., Ryan, J., Doherty, E., Mohammed, H., et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. (2016). Nature, 529(7586), 413-417. PMCID: PMC4854653.