James Hoch, PhD

Professor Emeritus
Department of Molecular Medicine
California Campus

Research Focus

The work in the laboratory focuses on the structure and function of signal transduction proteins regulating gene expression for virulence and prokaryotic development in sporulating bacteria.


Ph.D., University of Illinois at Urbana-Champaign, 1965

Professional Experience

2016-2017 Professor Emeritus, Molecular and Experimental Medicine (MEM), Scripps Research
-2016 Professor, Molecular and Experimental Medicine (MEM), Scripps Research

Awards & Professional Activities

Faculty Research Awardee, American Cancer Society
Editorial Board, Molecular Microbiology

Selected References

All Publications

Szurmant, H., Bu, L., Brooks III, C.L. and Hoch, J.A. An essential sensor histidine kinase regulated by TM helix interactions with its auxiliary proteins. PNAS. 105(15):5891-6. 2008

Szurmant, H., White, R.A. and Hoch, J.A. Sensor complexes regulating two-component signal transduction. Curr. Opin. Struct. Biol. 17(6):706-15. 2007

White, R.A., Szurmant, H., Hoch, J.A. and Hwa, T. Features of protein-protein interactions in two-component signaling deduced from genomic libraries. Methods Enzymol. 422:75-101. 2007