Floyd Bloom, MD

Professor Emeritus
Business Administration
California Campus



Research Focus

Chemical Neuroanatomy

Within the context of our Department's overall research program, my efforts have focussed on the structural and histochemical analysis of brain regions in which other faculty analyze changes occurring with drug actions. My research employs light and electron microscopy to determine the organization and chemical neuro-anatomic relationships that define how and where a drug can produce its effects at the cellular and systems level to understand the mechanisms by which drugs can affect overall brain function and to combat brain diseases.


Education

M.D. (Medicine), Washington University in St. Louis, School of Medicine, 1960
A.B. (German Literature), Southern Methodist University, 1956

Awards & Professional Activities

Presidential Plenary Lecturer, CINP, Paris Salmon Award, New York Academy of Sciences Walsh McDermott Award, Institute of Medicine Co-Chair, Report Review Committee, National Research Council, National Academy of Science Doctor of Science, hon. caus., Southern Methodist University Doctor of Science, hon. caus., Hahnemann University, Philadelphia Doctor of Science, hon. caus., University of Rochester, New York Doctor of Science, hon. caus. Mt. Sinai Sch of Medicine, NY Honorary Doctor of Science, Thomas Jefferson University, Philadelphia Doctor of Science, hon. caus., Washington University Chairman, Lashley Awards Committee, American Philosophical Society.

Selected References

All Publications

Bloom, F.E. Presidential address. Science as a way of life: perplexities of a physician-scientist. Science 300(5626):1680-1685, 2003.

Redwine, J.M., Kosofsky, B., Jacobs, R.E., Games, D., Reilly, J.F., Morrison, J.H., Young, W.G., Bloom, F.E. Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis. Proc Natl Acad Sci USA 100(3):1381-1386, 2003.

Reilly, J.F., Games, D., Rydel, R.E., Freedman, S., Schenk, D., Young, W.G., Morrison, J.H., Bloom, F.E. Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model. Proc Natl Acad Sci USA 100(8):4837-4842, 2003.

Wu, C.C., Chawla, F., Games, D., Rydel, R.E., Freedman, S., Schenk, D., Young, W.G., Morrison, J.H., Bloom, F.E. Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses. Proc Natl Acad Sci USA 101(18):7141-7146, 2004.

Bloom FE. The catecholamine neuron: Historical and future perspectives. ProgNeurobiol. 2010 Feb 9;90(2):75-81.