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Welcome to the Hollis Cline Lab
Lab Members

Tyler Wishard, B.S.

Research Technician
(June 2015 - present)

Intern Research
(July, 2010 - June 2015)


University of California, San Diego (2010 - 2015)
Division of Biology, Physiology & Neuroscience, B.S.  

Project Description:

Brain development requires strict spatial and temporal regulation of cell proliferation, survival, differentiation and migration, so errors in the regulation of neurogenesis will have profound effects on brain development and function. I use in vivo electroporation of morpholino and DNA constructs to investigate the function of essential proteins in neuronal proliferation and differentiation in the central nervous system of Xenopus laevis tadpoles. I image in vivo using fluorescent protein markers in neuronal progenitor cells to track the progenitor cells and their neuronal progeny over time in live animals. These methods will elucidate the control of these proteins on neurogenesis and the neuropathological defects that arise from their dysregulation.  

Photo of a frog

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