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Welcome to the Hollis Cline Lab
Lab Members
Haiyan He Haiyan He, Ph.D.
Research Associate (8/2008 – present)
Ph.D. University of Maryland, College Park, 2007

I’m interested in the development and plasticity of GABAergic neurons. Very little is known about the GABAergic neurons in the tectum of tadpoles. On the other hand, the transparent albino Xenopus tadpole provides a perfect animal model to study single neuronal morphology as well as experience-dependent structural plasticity in vivo. My work focuses on characterizing the tectal GABAergic neurons with different biochemical markers, comparing and contrasting activity-dependent structural plasticity in GABAergic and non-GABAergic neurons in response to variant visual experience with or without perturbations of excitatory or inhibitory inputs.


He, H, Cline HT. (2011) Diadem X: Automated 4 Dimensional Analysis of Morphological Data. J.  Neuroinformatics
Shen W, Da Silva JS, He H, Cline HT. (2009) Type A GABA-receptor-dependent synaptic transmission sculpts dendritic arbor structure in Xenopus tadpoles in vivo. J Neurosci. 29: 5032-43.

He HY, Ray B, Dennis K, Quinlan EM. (2007) Experience-dependent recovery of vision following life-long deprivation amblyopia. Nat. Neurosci. 10: 1134-6.

He HY, Hodos W, Quinlan EM.  (2006) Visual deprivation reactivates rapid ocular dominance plasticity in adult visual cortex. J. Neurosci, 26: 2951-5.

He HY, Rasmusson DD, Quinlan EM. (2004) Progressive elevations in AMPA and GABAA receptor levels in deafferented somatosensory cortex. J. Neurochem., 90:  1186-1193.