• Carlos F. Barbas, III, Ph.D.

    Kellogg Professor and Chair in Molecular Biology
    The Skaggs Institute for Chemical Biology
    and the Departments of Chemistry and Cell & Molecular Biology

  •   The Scripps Research Institute
    10550 North Torrey Pines Rd.
    La Jolla, CA 92037

  • Carlos F. Barbas, III, Ph.D. 
    Roberta  Fuller, Sr. Res. Assistant 
    Thom  Gaj, Ph.D. 
    Jarlath  Garcia 
    Xianxing  Jiang, Ph.D. 
    Brian  Lamb, Ph.D. 
    Robyn  Leary, Ph.D. 
    Jia  Liu, Ph.D. 
  • Mishelle  McClanahan-Shinn 
    Pedro  Perdigão 
    Bianca  Romana 
    Jingjing  Song 
    Mark  Wallen 
    Wei  Zhang, Ph.D. 
    Michael  Zorniak, Ph.D. 


 348-329  of  348   First  Previous   Next  Last    Year  

348 ]  Liu, J.; Gaj, T.; Wallen, M.C.; Barbas III, C.F. (2015) Improved Cell-Penetrating Zinc-Finger Nuclease Proteins for Precision Genome Engineering  
  Molecular Therapy - Nucleic Acids  4, e232


347 ]  Asano, S.; Gavrilyuk, J.; Burton, D.R.; Barbas III, C.F. (2014) Preparation and Activities of Macromolecule Conjugates of the CCR5 Antagonist Maraviroc 
  ACS Med. Chem. Letters  5(2), 133-137


346 ]  Asano, S.; Patterson, J.T.; Gaj, T.; Barbas III, C.F. (2014) Site-selective labeling of a lysine residue in human serum albumin. (Due to copyright restrictions, we are unable to provide this manuscript online. Please see http://dx.10.1002/anie.201405924 for the paper or email us for an electronic reprint.)  
  Angew Chem Int Ed Engl  53(44), 11783-11786

345 ]  Cheng, D.; Ishihara, Y.; Tan, B.; Barbas III, C.F. (2014)  Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies 
  ACS Catalysis  4, 743–762


344 ]  Gaj, T.; Barbas III, C.F. (2014) Genome Engineering with Custom Recombinases 
  Methods in Enzymology  546, 79-91


343 ]  Gaj, T.; Liu, J.; Anderson, K.E.; Sirk, S.J.; Barbas III, C.F. (2014) Protein delivery using Cys2-His2 zinc-finger domains 
  ACS Chem Biol  9(8), 1662-1667


342 ]  Gaj, T.; Sirk, S.J.; Tingle, R.; Mercer, A.C.; Wallen, M.; Barbas III, C.F.  (2014) Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. 
   Journal of the American Chemical Society  136(13), 5047-5056


341 ]  Gersbach, C.A.; Gaj, T.; Barbas III, C.F. (2014) Synthetic Zinc Finger Proteins: The Advent of Targeted Gene Regulation and Genome Modification Technologies 
  Accounts of Chemical Research  47, 2309-2318


340 ]  Lamb, B.M.; Barbas III, C.F. (2014) Selective Arylthiolane Deprotection by Singlet Oxygen: A Promising Tool for Sensors and Prodrugs 
  Chem Comm  In press, 

339 ]  Liu, J.; Gaj, T.; Patterson, J.T.; Sirk, S.J.; Barbas III, C.F. (2014) Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering 
  PlosOne  9(1), e85755


338 ]  Mercer, A.C.; Gaj, T.; Sirk, S.J.; Lamb, B.M.; Barbas III, C.F.  (2014) Regulation of Endogenous Human Gene Expression by Ligand-Inducible TALE Transcription Factors 
  ACS Synth Biol  3(10), 723-30


337 ]  Patterson, J.T.; Asano, S.; Li, X.; Rader, C.; Barbas III, C.F. (2014) Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers 
  Bioconjug Chem  25(8), 1402–1407


336 ]  Sirk, S.J.; Gaj, T.; Jonsson, A.; Mercer, A.C.; Barbas III, C.F. (2014) Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants 
  Nucleic Acids Res  42(7), 4755-4766


335 ]  Albertshofer, K.; Tan, B.; Barbas III, C.F.  (2013) Asymmetric Construction of Spirocyclopentenebenzofuranone Core Structures via Highly Selective Phosphine-Catalyzed [3 + 2] Cycloaddition Reactions 
  Org. Lett.  15(12), 2958-2961


334 ]  Ban, H.; Nagano, M.; Gavrilyuk, J.; Hakamata, W.; Inokuma, T.; Barbas III, C.F. (2013) Facile and Stabile Linkages through Tyrosine: Bioconjugation Strategies with the Tyrosine-Click Reaction 
  Bioconj. Chem.  24(4), 520-32


333 ]  Gaj, T.; Gersbach, C.A.; Barbas III, C.F. (2013) ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering 
  Trends in Biotechnology  31(7), 397-405


332 ]  Gaj, T.; Mercer, A.C.; Sirk, S.J.; Smith. H.L.; Barbas III, C.F. (2013) A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells 
  Nucleic Acids Res  41(6), 3937-3946


331 ]  Gaj, T.; Sirk, S.J.; Barbas III, C.F. (2013) Expanding the Scope of Site-Specific Recombinases for Genetic and Metabolic Engineering.
(Due to copyright restrictions, we are unable to provide this manuscript online. Please see http://dx.doi.org/10.1002/bit.25096 for the paper or email us for an electronic reprint.)  
  Biotech and Bioeng  111(1), 1-15

330 ]  Gavrilyuk, J.; Ban, H.; Uehara, H.; Sirk, S.J.; Saye-Francisco, K.; Cuevas, A.; Zablowsky, E.; Oza, A.; Seaman, M.S.; Burton, D.R.; Barbas III, C.F. (2013) Antibody Conjugation Approach Enhances Breadth and Potency of Neutralization of Anti-HIV-1 Antibodies and CD4-IgG 
  J. Virol.  87(9), 4985-4993


329 ]  Jiang, X.; Tan, B.; Barbas III, C.F. (2013) Core-Structure-Motivated Design of Iminium–Enolate Organocascade Reactions: Enantioselective Syntheses of 5,6-Dihydroindolizines.
(Due to copyright restrictions, we are unable to provide this manuscript online. Please see http://dx.doi.org/10.1002/anie.201303300 for the paper or email us for an electronic reprint.) 
  Angew. Chem. Int. Ed.  52(35), 9261-9265

 348-329  of  348   First  Previous   Next  Last