The Proteomics Core provides mass spectrometry-based proteomics services, focusing on quantitative proteomics using label-free or multiplexed analysis. Services include analysis of samples from a wide variety of experimental designs, including but not limited to: proximity and metabolic labeling, drug target discovery, comparative analysis of affinity-based enrichments, protein-protein interactions, and post-translational modifications. Services include assistance with experimental design and data analysis.

The Mass Spectrometry Core provides advanced expertise in mass spectrometry, metabolomics, lipidomics, protein analysis, pharmacology, and quantitative analysis. We support researchers through high-quality analytical workflows that enable molecular discovery and biomarker identification, and precise measurement of metabolites, lipids, proteins, and drugs across diverse biological, biomedical, and translational research applications. We also provide six mass spectrometers for Open Access analyses.

Small molecule X-ray crystallographic services are provided by the UCSD X-Ray Crystallography Facility, located one mile away from Scripps Research. The facility provides data collection, processing, and analysis for small molecule structure determination, including determination of absolute stereochemistry.

Scripps Research’s Kresge Library helps our research community find, evaluate, create, and use information to empower scientific discovery and improve human health. We strategically curate and share scholarly content, and develop trainings, partnerships, and user-centered tools that connect researchers with resources at any time and from anywhere.

Most rare diseases begin with a single malfunction: a misfolded protein, a genetic mutation, a faulty cellular pathway. Our scientists work together to reveal the different underpinnings of rare diseases,…

Addiction is a chronic, relapsing disorder that can drive compulsive substance use despite harmful consequences. In 2024, an estimated 48.5 million people aged 12 or older in the U.S. had a substance use…

Today, severe respiratory conditions are the third leading cause of death around the globe, ranging from the hundreds of millions of people impacted by widespread diseases like chronic obstructive pulmonary…

Infectious diseases remain leading causes of mortality and disability in underprivileged areas, according to the World Health Organization, and many diseases are spreading to previously unaffected regions.  Infectious diseases are illnesses caused by…