Yong Zhao, Ph.D.
Molecular Graphics Laboratory
Contact:
Research Associate
The Scripps Research Institute,
Dept. Molecular Biology, MB-5,
10550 North Torrey Pines Road,
La Jolla, CA 92037-1000, USA.
Tel: (858) 784-2842
Fax: (858) 784-2860
email: yongzhao _at_ scripps.edu

Research at Scripps:
Computational represetation of FLEXIBLE proteins
Representation of Flexible Biomolecular shapes (Principal Investigator: Dr. Michel Sanner) Founded by National Institute of General Medical Sciences, National Institutes of Health, BISTI, R21/R33 GM65609, 2003-2007  
Computational Structural Biology: The application of Induced-fitting Docking


AutoDock Package from our lab


My work on Docking ligand to a flexible protein -- the FLIPDock Package


Selected Publication:
  1. Yong Zhao; Michel Sanner. "Protein-ligand docking with multiple flexible side chains." J Comput Aided Mol Des. 2007 Nov 22;[Full Text]
  2. Yong Zhao; Michel Sanner. "FLIPDock: Docking flexible ligands into flexible receptors." Proteins. 2007 Aug 15;68(3):726-37. [Full Text] Go to FLIPDock site
  3. Yong Zhao; Daniel Stoffler; Michel Sanner "Hierarchical and multi-resolution representation of protein flexibility." Bioinformatics 2006 22(22):2768-2774 [Full Text]
  4. Yong Zhao; Thomas Cundari. "DFT study on Suzuki Coupling Reaction" manuescript in preparation.
  5. Thomas Cundari. Jun Deng Yong Zhao;  "ONIOM study of the active species in Pd-phosphine catalyzed coupling reactions. " THEOCHEM (2003), 632 121-129.
  6. Saha, Rajendra; Bhattacharyya, S. P.; Taylor, Christopher D.; Zhao, Yong; Cundari, Thomas R. "Direct solution of the Schroedinger equation by a parallel genetic algorithm: Cases of an exactly solvable 2-D interacting oscillator and the hydrogen atom  International Journal of Quantum Chemistry (2003), 94(5), 243-250.
  7. Katharine D. Cooney, Thomas R. Cundari, Norris W. Hoffman, Karl A. Pittard, M. Danielle Temple, and Yong Zhao. "A Priori Assessment of the Stereoelectronic Profile of Phosphines and Phosphites " J. of the American Chemical Society (2003), 125(14), 4318-4324
  8. Cundari, Thomas R; Yong Zhao. "Novel Transition Metal Multiple Bonding Myth or Reality? A Computational Study of Boryl Complexes " Inorganica Chimica Acta (2003), 345 70-80.
  9. Thomas Cundari; Jun Deng; Yong Zhao "Design of a Propane Ammoxidation Catalyst Using Artificial Neural Networks and Genetic Algorithms." Industrial & Engineering Chemistry Research (2001), 40(23), 5475-5480.
Programming:
Python, (application in Bioscience)
C++ (7+ years of experience)

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Last Updated at Tuesday, 18-Dec-2007 12:44:25 PST