(Virus Structure Database)
3D-Structure, Design and Informatics
Our laboratory interests include
Three dimensional structural analyses of Viral capsids and proteins
Structural Bioinformatics and Homology Modeling
Functional Capsid and Protein Design.
Currently, our work focuses on 3D-structural analyses of viral capsids and proteins, informatics and design of capsids with new and novel functionalities. We use viral capsids as platforms for polyvalent display of antigenic epitopes to generate customized vaccines of interest.
We employ methods in Structural biology: X-ray crystallography, electron microscopy
Bioinformatics: relational databases and data-mining
Molecular Biology: protein design, expression