Scripps Research Logo

Valente Lab Publications

Research image

Cari F. Kessing, Christopher C. Nixon, Chuan Li, Perry Tsai, Hiroshi Takata, Guillaume Mousseau, Phong T. Ho, Jenna B. Honeycutt, Mohammad Fallahi, Lydie Trautmann, J. Victor Garcia & Valente, S.T. (2017) In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a ‘‘Block-and-Lock’’ Strategy for HIV-1 Treatment. Cell Reports. 21-3:600-611(http://www.cell.com/cell-reports/fulltext/S2211-1247(17)31385-2)

Mousseau G.& Valente, S.T. (2017) Optimizing In Vitro Pre-mRNA 3′ Role of Host Factors on the Regulation of Tat-Mediated Transcription. Current Pharmaceutical Design. Accepted (Future PubMed Link)

Mihwa Na, Susana T. Valente, & Kevin Ryan (2016) Optimizing In Vitro Pre-mRNA 3′ Cleavage Efficiency:Reconstitution from Anion-Exchange Separated HeLa Cleavage Factors and from Adherent HeLa Cell Nuclear Extract. Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation:Methods in Biology. 1507:179-198 (PubMed Link)

Sonia Mediouni, Maria Cecilia Garibaldi Marcondes, Courtney Miller, Jay P. McLaughlin & Valente, S.T. (2015) The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders. Frontiers in Microbiology, section Virology. 6: 1164. (PubMed Link)

Thenin-Houssier S. & Valente, S.T. (2015) HIV-1 capsid inhibitors as antiretroviral agents. Review. Curr HIV Res. 14(3):270-82. (PubMed Link)

Mousseau G., Kessing C.F., Fromentin R., Trautmann L., Chomont N. & Valente, S.T. (2015) The Tat inhibitor didehydro-Cortistatin A prevents HIV-1 reactivation from latency. mBio 6(4): e00465-15 (PubMed Link)

Mousseau, G. Mediouni, S. & Valente, S.T. (2015) Targeting HIV transcription: the quest for a functional cure. Current Topics in Microbiology and Immunology. Series on novel and future small molecule treatments for HIV 389:121-45. doi: 10.1007/82_2015_435 (PubMed Link)

Mediouni, S., Jablonski, J., Paris, J.J., Clementz, M., Thenin-Houssier, S., McLaughlin, J.P. & Valente, S.T. (2015) Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation and Prevents Potentiation of Cocaine Reward in Tat Transgenic Mice. Current HIV Research 13(1):64-79 ( PubMed Link)

Jablonski, J., Clementz, M., Ryan, K., & Valente, S.T. (2014) Analysis of RNA processing reactions using cell free systems: 3' end cleavage of pre-mRNA substrates in vitro. Journal of Visualiized Experiments: JoVE (87), e51309, doi:10.3791/51309 (PubMed Link)

Mousseau, G. & Valente, S.T. (2012) Strategies to block HIV transcription: focus on small molecule Tat inhibitors.  Biology 1(3):668-697. (PubMed Link)

Mousseau, G., Clementz, M., Bakeman, W., Nagarsheth, N., Cameron, M., Shi, J., Baran, P. Fromentin, R., Chomont, N. & Valente, S.T. (2012) An analog of the Natural Steroidal Alkaloid Cortistatin A potently suppresses Tat-dependent HIV transcription. Cell Host and Microbe 12(1):97-108. (PubMed Link)

Valente, S.T., Gilmartin, G.M., Venkataraman, K., Arriagada, G., & Goff, S.P. (2009) HIV-1 mRNA 3’ end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8. Molecular Cell 23;36(2):279-89. (PubMed Link)

Valente, S.T., Gilmartin, G.M., Mott, C., Falkard, B., & Goff, S.P. (2009) Inhibition of HIV-1 replication by eIF3f. Proc Natl Acad Sci U S A 106:4071-4078. (PubMed Link)

Valente, S.T. & Goff, S.P. (2009) Somatic Cell Genetic Analyses to Identify HIV-1 Host Restriction Factors. Methods Molecular Biology 485:235-255. (PubMed Link)

Naghavi, M. H., Valente, S., Hatziioannou, T., de Los Santos, K., Wen, Y., Mott, C., Gundersen, G.G., & Goff, S.P. (2007) Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells.Embo Journal 26:41-52. (PubMed Link)

Valente, S. & Goff, S.P. (2006) Inhibition of HIV-1 Gene Expression by a Fragment of hnRNP U. Molecular Cell 23:597-605. (PubMed Link)

Hazan, U., Romero, I. A., Cancello, R., Valente, S., Perrin, V., Mariot, V., Dumonceaux, J., Gerhardt, C.C., Strosberg, A.D., Couraud, P.O., et al. (2002) Human adipose cells express CD4, CXCR4, and CCR5 [corrected] receptors: a new target cell type for the immunodeficiency virus-1? Faseb Journal 16:1254-1256. (PubMed Link)

Valente, S.T., Chanel, C., Dumonceaux, J., Olivier, R., Marullo, S., Briand, P., & Hazan, U. (2001) CXCR4 is down-regulated in cells infected with the CD4-independent X4 human immunodeficiency virus type 1 isolate m7NDK. Journal of Virology 75:439-447.  (PubMed Link)

Dumonceaux, J. Chanel, C., Valente, S., Quivet, L., Briand, P, & Hazan, U. (1999) Mutations in the env gene of human immunodeficiency virus type 1 NDK isolates and the use of African green monkey CXCR4 as a co-receptors in COS-7 cells. Journal of General Virology 80:1975-1982. (PubMed Link)

___________

Home
___________

Projects
___________

Lab Members
___________

Publications
___________

Funding
___________

Positions
___________

Links
___________

Lab Photos
___________

Life in Jupiter
___________

In The Press
___________

Support Us
___________

Contacts
___________