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Click Chemistry Publications

937 Zhang, Y.-H.; Gao, Z.-X.; Zhong, C.-L.; Zhou, H.-B.; Chen, L.; Wu, W.-M.; Peng, X.-J.; Yao, Z.-J. An Inexpensive Fluorescent Labeling Protocol for Bioactive Natural Products Utilizing Cu(I)-Catalyzed Huisgen Reaction. Tetrahedron 2007, 63, 6813-6821.
936 Zhang, X.; Hsung, R. P.; Li, H. A Triazole-Templated Ring-Closing Metathesis for Constructing Novel Fused and Bridged Triazoles. Chem. Commun. 2007, 2420-2422.
935 Zhang, J.; Chen, H.-N.; Chiang, F.-I.; Takemoto, J. Y.; Bensaci, M.; Chang, C.-W. T. Sonication-Assisted Library Synthesis of Oxazolidinone-Carbohydrate Conjugates. J. Comb. Chem. 2007, 9, 17-19.
934 Zhan, W.-H.; Wu, W.-J.; Hua, J.-L.; Jing, Y.-H.; Meng, F.-S.; Tian, H. Photovoltaic Properties of New Cyanine-Naphthalimide Dyads Synthesized by 'Click' Chemistry. Tetrahedron Lett. 2007, 48, 2461-2465.
933 Zeng, Q.; Li, T.; Cash, B.; Li, S.; Xie, F.; Wang, Q. Chemoselective Derivatization of a Bionanoparticle by Click Reaction and ATRP Reaction. Chem. Commun. 2007, 1453-1455.
932 Yoon, K.; Goyal, P.; Weck, M. Monofunctionalization of Dendrimers with Use of Microwave-Assisted 1,3-Dipolar Cycloadditions. Org. Lett. 2007, 9, 2051-2054.
931 Yoo, E. J.; Ahlquist, M.; Kim, S. H.; Bae, I.; Fokin, V. V.; Sharpless, K. B.; Chang, S. Copper-Catalyzed Synthesis of N-Sulfonyl-1,2,3-Triazoles: Controlling Selectivity. Angew. Chem., Int. Ed. 2007, 46, 1730-1733.
930 Yoo, B. K.; Joo, S.-W. In situ Raman Monitoring Triazole Formation from Self-Assembled Monolayers of 1,4-Diethynylbenzene on Ag and Au Surfaces via "Click" Cyclization. J. Colloid Interface Sci. 2007, 311, 491-496.
929 Yang, D.; Fu, N.; Liu, Z.; Li, Y.; Chen, B. A Convenient Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles via 1,3-Dipolar Cycloaddition/Coupling of Alkynes, Phenylboronic Acids, and Sodium Azide Catalyzed by Cu(I)/Cu(II). Synlett 2007, 278-282.
928 Yan, Z.-Y.; Niu, Y.-N.; Wei, H.-L.; Wu, L.-Y.; Zhao, Y.-B.; Liang, Y.-M. Combining Proline and 'Click Chemistry': a Class of Versatile Organocatalysts for the Highly Diastereo- and Enantioselective Michael Addition in Water. Tetrahedron: Asymmetry 2007, 17, 3288-3293.
927 Xu, N.; Lu, F.-Z.; Du, F.-S.; Li, Z.-C. Synthesis of Saccharide-Terminated Poly(ε-caprolactone) via Michael Addition and 'Click' Chemistry. Macromol. Chem. Phys. 2007, 208, 730-738.
926 Xie, J.; Seto, C. T. A Two Stage Click-Based Library of Protein Tyrosine Phosphatase Inhibitors. Bioorg. Med. Chem. 2007, 15, 458-473.
925 Xia, Y.; Li, W.; Qu, F.; Fan, Z.; Liu, X.; Berro, C.; Rauzy, E.; Peng, L. Synthesis of Bitriazolyl Nucleosides and Unexpectedly Different Reactivity of Azidotriazole Nucleoside Isomers in the Huisgen Reaction. Org. Biomol. Chem. 2007, 5, 1695-1701.
924 Wu, P.; Fokin, V. V. Catalytic Azide-Alkyne Cycloaddition: Reactivity and Applications. Aldrichim. Acta 2007, 40, 7-17.
923 Wu, P.; Fokin, V.; Sharpless, K. B., Method of Using Click Chemistry to Functionalize Dendrimers, 2006-US27924, 2007011967, 20060718.
922 Wu, P.; Fokin, V.; Sharpless, K. B., Method for Making Amphiphilic Diblock Dendrimers by Click Chemistry, 2006-US28017, 2007012001, 20060718.
921 Wolfheis, O. S. The Click Reaction in the Luminescent Probing of Metal Ions, and Its Implication on Biolabeling Techniques. Angew. Chem., Int. Ed. 2007, 46, 2980-2982.
920 Witczak, Z. J.; Lorchak, D.; Nguyen, N. A Click Chemistry Approach to Glycomimetics: Michael Addition of 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranose to 4-deoxy-1,2-O-isopropylidene-L-glycero-pent-4-enopyranos-3-ulose - a Convenient Route to Novel 4-deoxy-(1->5)-5-C-thiodisaccharides. Carbohydr. Res. 2007, 342, 1929-1933.
919 Wilkinson, B. L.; Bornaghi, L. F.; Houston, T. A.; Innocenti, A.; Vullo, D.; Supuran, C. T.; Poulsen, S.-A. Carbonic Anhydrase Inhibitors: Inhibition of Isozymes I, II, and IX with Triazole-Linked O-Glycosides of Benzene Sulfonamides. J. Med. Chem. 2007, 50, 1651-1657.
918 Westlund, R.; Glimsdal, E.; Lindgren, M.; Lopes, C.; Malmstroem, E. Click Chemistry and Dendrimer Synthesis as Tools for Designing Efficient Optical Power Limiting Platinum(II) Acetylides. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 537-538.
917 Weisbrod, S. H.; Marx, A. A Nucleoside Triphosphate for Site-Specific Labelling of DNA by the Staudinger Ligation. Chem. Commun. 2007, 1828-1830.
916 Wang, Z.-X.; Zhao, Z.-G. Synthesis of 1,4-Disubstituted 1,2,3-Triazoles via a Three-Component Reaction in Water in the Presence of CuX (X = Cl, I). J. Heterocycl. Chem. 2007, 44, 89-92.
915 Wang, J.; Li, H.; Zou, G.; Wang, L.-X. Novel Template-Assembled Oligosaccharide Clusters as Epitope Mimics for HIV-Neutralizing Antibody 2G12. Design, Synthesis, and Antibody Binding Study. Org. Biomol. Chem. 2007, 5, 1529-1540.
914 Voit, B. The Potential of Cycloaddition Reactions in the Synthesis of Dendritic Polymers. New J. Chem. 2007, 31, 1139-1151.
913 Vogt, A. P.; Gondi, S. R.; Sumerlin, B. S. Hyperbranched Polymers via RAFT Copolymerization of an Acryloyl Trithiocarbonate. Aust. J. Chem. 2007, 60, 396-399.
912 Voggu, R.; Suguna, P.; Chandrasekaran, S.; Rao, C. N. R. Assembling Covalently Linked Nanocrystals and Nanotubes through Click Chemistry. Chem. Phys. Lett. 2007, 443, 118-121.
911 Vlahov, I. R.; Santhapuram, H. K. R.; Wang, Y.; Kleindl, P. J.; You, F.; Howard, S. J.; Westrick, E.; Reddy, J. A.; Leamon, C. P. An Assembly Concept for the Consecutive Introduction of Unsymmetrical Disulfide Bonds: Synthesis of a Releasable Multidrug Conjugate of Folic Acid. J. Org. Chem. 2007, 72, 5968-5972.
910 Vestberg, R.; Malkoch, M.; Kade, M.; Wu, P.; Fokin, V. V.; Sharpless, K. B.; Drockenmuller, E.; Hawker, C. J. Role of Architecture and Molecular Weight in the Formation of Tailor-Made Ultrathin Multilayers Using Dendritic Macromolecules and Click Chemistry. J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 2835-2846.
909 van Kasteren, S. I.; Kramer, H. B.; Jensen, H. H.; Campbell, S. J.; Kirkpatrick, J.; Oldham, N. J.; Anthony, D. C.; Davis, B. G. Expanding the Diversity of Chemical Protein Modification Allows Post-Translational Mimicry. Nature (London) 2007, 446, 1105-1109.
908 Van Dijk, M.; Mustafa, K.; Dechesne, A. C.; Van Nostrum, C. F.; Hennink, W. E.; Rijkers, D. T. S.; Liskamp, R. M. J. Synthesis of Peptide-Based Polymers by Microwave-Assisted Cycloaddition Backbone Polymerization. Biomacromolecules 2007, 8, 327-330.
907 Tsarevsky, N. V.; Bencherif, S. A.; Matyjaszewski, K. Graft Copolymers by a Combination of ATRP and Two Different Consecutive Click Reactions. Macromolecules 2007, 40, 4439-4445.
906 Touaibia, M.; Shiao, T. C.; Papadopoulos, A.; Vaucher, J.; Wang, Q.; Benhamioud, K.; Roy, R. Tri- and Hexavalent Mannoside Clusters as Potential Inhibitors of Type 1 Fimbriated Bacteria Using Pentaerythritol and Triazole Linkages. Chem. Commun. 2007, 380-382.
905 Ting, S. R. S.; Granville, A. M.; Quemener, D.; Davis, T. P.; Stenzel, M. H.; Barner-Kowollik, C. RAFT Chemistry and Huisgen 1,3-Dipolar Cycloaddition: A Route to Block Copolymers of Vinyl Acetate and 6-O-Methacryloyl Mannose? Aust. J. Chem. 2007, 60, 405-409.
904 Thomassin, J.-M.; Lenoir, S.; Riga, J.; Jerome, R.; Detrembleur, C. Grafting of Poly[2-(tert-butylamino)ethyl methacrylate] onto Polypropylene by Reactive Blending and Antibacterial Activity of the Copolymer. Biomacromolecules 2007, 8, 1171-1177.
903 Taylor, P.; Kovarik, Z.; Reiner, E.; Radic, Z. Acetylcholinesterase: Converting a Vulnerable Target to a Template for Antidotes and Detection of Inhibitor Exposure. Toxicology 2007, 233, 70-78.
902 Tao, C.-Z.; Cui, X.; Li, J.; Liu, A.-X.; Liu, L.; Guo, Q.-X. Copper-Catalyzed Synthesis of Aryl Azides and 1-Aryl-1,2,3-Triazoles from Boronic Acids. Tetrahedron Lett. 2007, 48, 3525-3529.
901 Szewczuk, L. M.; Culhane, J. C.; Yang, M.; Majumdar, A.; Yu, H.; Cole, P. A. Mechanistic Analysis of a Suicide Inactivator of Histone Demethylase LSD1. Biochemistry 2007, 46, 6892-6902.
900 Szalai, M. L.; McGrath, D. V.; Wheeler, D. R.; Zifer, T.; McElhanon, J. R. Dendrimers Based on Thermally Reversible Furan-Maleimide Diels-Alder Adducts. Macromolecules 2007, 40, 818-823.
899 Suijkerbuijk, B. M. J. M.; Aerts, B. N. H.; Dijkstra, H. P.; Lutz, M.; Spek, A. L.; van Koten, G.; Klein Gebbink, R. J. M. "Click" 1,2,3-Triazoles as Tunable Ligands for Late Transition Metal Complexes. Dalton Trans. 2007, 1273-1276.
898 Such, G. K.; Tjipto, E.; Postma, A.; Johnston, A. P. R.; Caruso, F. Ultrathin, Responsive Polymer Click Capsules. Nano Lett. 2007, 7, 1706-1710.
897 Srinivasachari, S.; Liu, Y.; Prevette, L. E.; Reineke, T. M. Effects of Trehalose Click Polymer Length on pDNA Complex Stability and Delivery Efficacy. Biomaterials 2007, 28, 2885-2898.
896 Specker, D.; Wittmann, V. Synthesis and Application of Glycopeptide and Glycoprotein Mimetics. Top. Curr. Chem. 2007, 267, 65-107.
895 Spain, S. G.; Gibson, M. I.; Cameron, N. R. Recent Advances in the Synthesis of Well-Defined Glycopolymers. J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 2059-2072.
894 Soutullo, M. D.; Odom, C. I.; Wicker, B. F.; Henderson, C. N.; Stenson, A. C.; Davis, J. H., Jr. Reversible CO2 Capture by Unexpected Plastic-, Resin-, and Gel-like Ionic Soft Materials Discovered during the Combi-Click Generation of a TSIL Library. Chem. Mater. 2007, 19, 3581-3583.
893 Sohma, Y.; Yoshiya, T.; Taniguchi, A.; Kimura, T.; Hayashi, Y.; Kiso, Y. Development of O-Acyl Isopeptide Method. Peptide Science 2007, 88, 253-262.
892 Smith, C. D.; Baxendale, I. R.; Tranmer, G. K.; Baumann, M.; Smith, S. C.; Lewthwaite, R. A.; Ley, S. V. Tagged Phosphine Reagents to Assist Reaction Work-up by Phase-Switched Scavenging Using a Modular Flow Reactor. Org. Biomol. Chem. 2007, 5, 1562-1568.
891 Smith, C. D.; Baxendale, I. R.; Lanners, S.; Hayward, J. J.; Smith, S. C.; Ley, S. V. [3 + 2] Cycloaddition of Acetylenes with Azides to Give 1,4-Disubstituted 1,2,3-Triazoles in a Modular Flow Reactor. Org. Biomol. Chem. 2007, 5, 1559-1561.
890 Skarpos, H.; Osipov, S. N.; Vorob'eva, D. V.; Odinets, I. L.; Lork, E.; Roeschenthaler, G.-V. Synthesis of Functionalized Bisphosphonates via Click Chemistry. Org. Biomol. Chem. 2007, 5, 2361-2367.
889 Sirion, U.; Kim, H. J.; Lee, J. H.; Seo, J. W.; Lee, B. S.; Lee, S. J.; Oh, S. J.; Chi, D. Y. An Efficient F-18 Labeling Method for PET Study: Huisgen 1,3-Dipolar Cycloaddition of Bioactive Substances and F-18-Labeled Compounds. Tetrahedron Lett. 2007, 48, 3953-3957.
888 Sieczkowska, B.; Millaruelo, M.; Messerschmidt, M.; Voit, B. New Photolabile Functional Polymers for Patterning onto Gold Obtained by Click Chemistry. Macromolecules 2007, 40, 2361-2370.
887 Shoichet, M. S.; Yuan, Y.; Shi, M.; Wosnick, J., Method of Biomolecule Immobilization on Polymers Using Click-Type Chemistry, 2006-CA1100, 2007003054, 20060706.
886 Shie, J.-J.; Fang, J.-M. Microwave-Assisted One-Pot Tandem Reactions for Direct Conversion of Primary Alcohols and Aldehydes to Triazines and Tetrazoles in Aqueous Media. J. Org. Chem. 2007, 72, 3141-3144.
885 Shen, Y.; Shen, Z.; Nieberle, J.; Barriau, E.; Frey, H. Azide End-Capped Hyperbranched Polyglycerol: Complex Polymer Structures via Click Chemistry. PMSE Prepr. 2007, 96, 603-604.
884 Shen, D.-M.; Liu, C.; Chen, Q.-Y. Synthesis and Versatile Reactions of β-Azidotetraarylporphyrins. Eur. J. Org. Chem. 2007, 2007, 1419-1422.
883 Shchetnikov, G. T.; Peregudov, A. S.; Osipov, S. N. Effective Pathway to the α-CF3-Substituted Azahistidine Analogues. Synlett 2007, 136-140.
882 Shafi, S.; Banday, A. H.; Ismail, T.; Kumar, H. M. S. Domino Addition/N-C Heterocyclization of Azides with Allenylmagnesium Bromide: Rapid Synthesis of 5-Butynyl-1,2,3-Triazoles. Synlett 2007, 1109-1111.
881 Seyler, H.; Berger-Nicoletti, E.; Kilbinger, A. F. M. Rod-Coil Copolymers from Oligo(p-benzamide) Foldamers. J. Mater. Chem. 2007, 17, 1954-1957.
880 Seela, F.; Sirivolu, V. R. Nucleosides and Oligonucleotides with Diynyl Side Chains: Base Pairing and Functionalization of 2'-Deoxyuridine Derivatives by the Copper(I)-Catalyzed Alkyne-Azide 'Click' Cycloaddition. Helv. Chim. Acta 2007, 90, 535-552.
879 Seela, F.; Peng, X.; Budow, S. Advances in the Synthesis of 7-Deazapurine - Pyrrolo[2,3-d]pyrimidine - 2'-Deoxyribonucleosides Including D- and L-Enantiomers, Fluoro Derivatives and 2',3'-Dideoxyribonucleosides. Curr. Org. Chem. 2007, 11, 427-462.
878 Seela, F.; Budow, S.; Leonard, P. Oligonucleotides Forming an i-motif: The pH-Dependent Assembly of Individual Strands and Branched Structures Containing 2'-Deoxy-5-propynylcytidine. Org. Biomol. Chem. 2007, 5, 1858-1872.
877 Schwartz, E.; Kitto, H. J.; de Gelder, R.; Nolte, R. J. M.; Rowan, A. E.; Cornelissen, J. J. L. M. Synthesis, Characterisation and Chiroptical Properties of 'Click'able Polyisocyanopeptides. J. Mater. Chem. 2007, 17, 1876-1884.
876 Schmidtchen, F. P. Isothermal Titration Calorimetry in Supramolecular Chemistry Analytical Methods in Supramolecular Chemistry 2007, 55-78.
875 Schlaad, H.; Boerner, H. G.; Taubert, A.; Stoeckel, N. Macromolecular Chemistry 2006 Nachrichten aus der Chemie 2007, 55, 306-312.
874 Schill, H.; de Meijere, A.; Yufit, D. S. Modular Synthesis of a New Family of Tripodal Ligands, all-cis-1,2,3-Tris(diphenylphosphinomethyl)cyclopropane and Relatives. Org. Lett. 2007, 9, 2617-2620.
873 Sadaghiani, A. M.; Verhelst, S. H. L.; Bogyo, M. Tagging and Detection Strategies for Activity-Based Proteomics. Curr. Opin. Chem. Biol. 2007, 11, 20-28.
872 Rusmini, F.; Zhong, Z.; Feijen, J. Protein Immobilization Strategies for Protein Biochips. Biomacromolecules 2007, 8, 1775-1789.
871 Riva, R.; Schmeits, S.; Jerome, C.; Jerome, R.; Lecomte, P. Combination of Ring-Opening Polymerization and "Click Chemistry": Toward Functionalization and Grafting of Poly(ε-caprolactone). Macromolecules 2007, 40, 796-803.
870 Riva, R.; Chafaqi, L.; Jerome, R.; Lecomte, P. Synthesis of New Substituted Lactones by "Click" Chemistry. ARKIVOC 2007, 292-306.
869 Ritschel, J.; Sasse, F.; Maier, M. E. Synthesis of a Benzolactone Collection using Click Chemistry. Eur. J. Org. Chem. 2007, 78-87.
868 Reddy, K. R.; Rajgopal, K.; Kantam, M. L. Copper-Alginates: a Biopolymer Supported Cu(II) Catalyst for 1,3-dipolar Cycloaddition of Alkynes with Azides and Oxidative Coupling of 2-Naphthols and Phenols in Water. Catal. Lett. 2007, 114, 36-40.
867 Ranjan, R.; Brittain, W. J. Combination of Living Radical Polymerization and Click Chemistry for Surface Modification. Macromolecules 2007, 40, 6217-6223.
866 Ranjan, R.; Brittain, W. J. Synthesis of Polyacrylamide-Silica Hybrid Nanoparticle using Raft Polymerization and Click Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 797-798.
865 Ramenda, T.; Bergmann, R.; Wuest, F. Synthesis of 18F-labeled Neurotensin(8-13) via Copper-Mediated 1,3-Dipolar [3+2]Cycloaddition Reaction. Lett. Drug Des. Discovery 2007, 4, 279-285.
864 Quader, S.; Boyd, S. E.; Jenkins, I. D.; Houston, T. A. Multi-Site Modification of Neomycin B: Combined Mitsunobu and Click Chemistry Approach. J. Org. Chem. 2007, 72, 1962-1979.
863 Qu, W.; Kung, M.-P.; Hou, C.; Oya, S.; Kung, H. F. Quick Assembly of 1,4-Diphenyltriazoles as Probes Targeting β-Amyloid Aggregates in Alzheimer's Disease. J. Med. Chem. 2007, 50, 3380-3387.
862 Qin, A.; Jim, C. K. W.; Lu, W.; Lam, J. W. Y.; Haeussler, M.; Dong, Y.; Sung, H. H. Y.; Williams, I. D.; Wong, G. K. L.; Tang, B. Z. Click Polymerization: Facile Synthesis of Functional Poly(aroyltriazole)s by Metal-Free, Regioselective 1,3-Dipolar Polycycloaddition. Macromolecules 2007, 40, 2308-2317.
861 Qin, A.; Jim, C. K. W.; Lam, J. W. Y.; Haussler, M.; Dong, Y.; Tang, B. Z. Facile Synthesis of Poly(aroyltriazole)s by Metal-Free 1,3-Dipolar Polycycloaddition (Click Polymerization). Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 400-401.
860 Punna, S.; Kaltgrad, E.; Finn, M. G. A Bioorthogonal Immobilization Method for Affinity Chromatography. American Biotechnology Laboratory 2007, 25, 20-21.
859 Pu, H.; Ye, S.; Wan, D. Anhydrous Proton Conductivity of Acid Doped Vinyltriazole-Based Polymers. Electrochim. Acta 2007, 52, 5879-5883.
858 Prevette, L. E.; Lynch, M. L.; Reineke, T. M. Understanding DNA Binding Mechanisms of Trehalose-Based Polymeric Gene Delivery Vectors. PMSE Prepr. 2007, 96, 843-844.
857 Prazeres, V. F. V.; Sanchez-Sixto, C.; Castedo, L.; Lamb, H.; Hawkins, A. R.; Riboldi-Tunnicliffe, A.; Coggins, J. R.; Lapthorn, A. J.; Gonzalez-Bello, C. Nanomolar Competitive Inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor Type II Dehydroquinase. ChemMedChem 2007, 2, 194-207.
856 Prakash, S.; Long, T. M.; Selby, J. C.; Moore, J. S.; Shannon, M. A. "Click" Modification of Silica Surfaces and Glass Microfluidic Channels. Anal. Chem. 2007, 79, 1661-1667.
855 Poulsen, T. B.; Bernardi, L.; Aleman, J.; Overgaard, J.; Jorgensen, K. A. Organocatalytic Asymmetric Direct α-Alkynylation of Cyclic β-Ketoesters. J. Am. Chem. Soc. 2007, 129, 441-449.
854 Plechkova, N. V.; Seddon, K. R. In Methods and Reagents for Green Chemistry 2007, p 105-130.
853 Pirali, T.; Gatti, S.; Di Brisco, R.; Tacchi, S.; Zaninetti, R.; Brunelli, E.; Massarotti, A.; Sorba, G.; Canonico, P. L.; Moro, L.; Genazzani, A. A.; Tron, G. C.; Billington, R. A. Estrogenic Analogues Synthesized by Click Chemistry. ChemMedChem 2007, 2, 437-440.
852 Partyka, D. V.; Updegraff, J. B., III; Zeller, M.; Hunter, A. D.; Gray, T. G. Carbon-Gold Bond Formation through [3 + 2] Cycloaddition Reactions of Gold(I) Azides and Terminal Alkynes. Organometallics 2007, 26, 183-186.
851 Parrish, B.; Emrick, T. Soluble Camptothecin Derivatives Prepared by Click Cycloaddition Chemistry on Functional Aliphatic Polyesters. Bioconjugate Chem. 2007, 18, 263-267.
850 Ortega-Munoz, M.; Morales-Sanfrutos, J.; Perez-Balderas, F.; Hernandez-Mateo, F.; Giron-Gonzalez, M. D.; Sevillano-Tripero, N.; Salto-Gonzalez, R.; Santoyo-Gonzalez, F. Click Multivalent Neoglycoconjugates as Synthetic Activators in Cell Adhesion and Stimulation of Monocyte/Machrophage Cell Lines. Org. Biomol. Chem. 2007, 5, 2291-2301.
849 Orlova, A. V.; Kondakov, N. N.; Kimel, B. G.; Kononov, L. O.; Kononova, E. G.; Sivaev, I. B.; Bregadze, V. I. Synthesis of Novel Derivatives of closo-Dodecaborate Anion with Azido Group at the Terminal Position of the Spacer. Appl. Organomet. Chem. 2007, 21, 98-100.
848 Opsteen, J. A.; Van Hest, J. C. M. Modular Synthesis of ABC Type Block Copolymers by "Click" Chemistry. J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 2913-2924.
847 Opsteen, J. A.; van Hest, J. C. M. Applications of Polymer Bioconjugates. Macromol. Eng. 2007, 4, 2645-2687.
846 Opsteen, J. A.; Brinkhuis, R. P.; Teeuwen, R. L. M.; Loewik, D. W. P. M.; van Hest, J. C. M. "Clickable" Polymersomes. Chem. Commun. 2007, 3136-3138.
845 Olsen, C. A.; Franzyk, H.; Jaroszewski, J. W. Aziridines in Parallel- and Solid-Phase Synthesis. Eur. J. Org. Chem. 2007, 2007, 1717-1724.
844 Odlo, K.; Hoydahl, E. A.; Hansen, T. V. One-Pot Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Terminal Acetylenes and in situ Generated Azides. Tetrahedron Lett. 2007, 48, 2097-2099.
843 O'Reilly, R. K.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L. Preparation of Orthogonally-Functionalized Core Click Cross-Linked Nanoparticles. New J. Chem. 2007, 31, 718-724.
842 O'Neil, E. J.; DiVittorio, K. M.; Smith, B. D. Phosphatidylcholine-Derived Bolaamphiphiles via Click Chemistry. Org. Lett. 2007, 9, 199-202.
841 Nolte, C.; Mayer, P.; Straub, B. F. Isolation of a Copper(I) Triazolide: a "Click" Intermediate. Angew. Chem., Int. Ed. 2007, 46, 2101-2103.
840 Nicolas, J.; Mantovani, G.; Haddleton, D. M. Living Radical Polymerization as a Tool for the Synthesis of Polymer-Protein/Peptide Bioconjugates. Macromol. Rapid Commun. 2007, 28, 1083-1111.
839 Nepogodiev, S. A.; Dedola, S.; Marmuse, L.; De Oliveira, M. T.; Field, R. A. Synthesis of Triazole-Linked Pseudo-Starch Fragments. Carbohydr. Res. 2007, 342, 529-540.
838 Nasrullah, M. J.; Vora, A.; Webster, D. C. Combination of ATRP and RAFT via "Click" Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 128-129.
837 Narayan, S.; Fokin, V. V.; Sharpless, K. B. In Organic Reactions in Water 2007, p 350-365.
836 Moses, J. E.; Moorhouse, A. D. The Growing Applications of Click Chemistry. Chem. Soc. Rev. 2007, 36, 1249-1262.
835 Miljanic, O. S.; Dichtel, W. R.; Khan, S. I.; Mortezaei, S.; Heath, J. R.; Stoddart, J. F. Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor-Acceptor [2]Catenanes. J. Am. Chem. Soc. 2007, 129, 8236-8246.
834 Merkx, R.; Van Haren, M. J.; Rijkers, D. T. S.; Liskamp, R. M. J. Resin-Bound Sulfonyl Azides: Efficient Loading and Activation Strategy for the Preparation of the N-Acyl Sulfonamide Linker. J. Org. Chem. 2007, 72, 4574-4577.
833 Macpherson, L. J.; Dubin, A. E.; Evans, M. J.; Marr, F.; Schultz, P. G.; Cravatt, B. F.; Patapoutian, A. Noxious Compounds Activate TRPA1 Ion Channels through Covalent Modification of Cysteines. Nature (London) 2007, 445, 541-545.
832 Lutz, J.-F. 1,3-Dipolar Cycloadditions of Azides and Alkynes: a Universal Ligation Tool in Polymer and Materials Science. Angew. Chem., Int. Ed. 2007, 46, 1018-1025.
831 Luo, J.; Pardin, C.; Zhu, X. X.; Lubell, W. D. Preparation, Characterization, and Application of Poly(vinyl alcohol)-graft-Poly(ethylene glycol) Resins: Novel Polymer Matrices for Solid-Phase Synthesis. J. Comb. Chem. 2007, 9, 582-591.
830 Lundberg, P.; Antoni, P.; Fogelstroem, L.; Malkoch, M.; Hult, A. Controlled Design of Amphiphilic Block-Copolymers Using Ring-Opening Polymerization and Click Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 407-408.
829 Lu, Z.; Zhang, Y.; Wulff, W. D. Direct Access to N-H-Aziridines from Asymmetric Catalytic Aziridination with Borate Catalysts Derived from Vaulted Binaphthol and Vaulted Biphenanthrol Ligands. J. Am. Chem. Soc. 2007, 129, 7185-7194.
828 Li, Y.; Benicewicz, B. C. Synthesis of Block Copolymers by a Combination of Raft Polymerization with Click Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 524-525.
827 Li, W.; Blankman, J. L.; Cravatt, B. F. A Functional Proteomic Strategy to Discover Inhibitors for Uncharacterized Hydrolases. J. Am. Chem. Soc. 2007, 129, 9594-9595.
826 Li, P.; Wang, L. One-Pot Synthesis of 1,2,3-Triazoles from Benzyl and Alkyl Halides, Sodium Azide and Alkynes in Water under Transition-Metal-Catalyst Free Reaction Conditions. Lett. Org. Chem. 2007, 4, 23-26.
825 Li, J.; Duan, M.; Fang, S.-W.; Zhang, L.-H. Synthesis of Cyclo-PMMA via Click Chemistry Combined with ATRP. Gaodeng Xuexiao Huaxue Xuebao 2007, 28, 1197-1199.
824 Li, H.; Riva, R.; Jerome, R.; Lecomte, P. Combination of Ring-Opening Polymerization and "Click" Chemistry for the Synthesis of an Amphiphilic Tadpole-Shaped Poly(ε-Caprolactone) Grafted by PEO. Macromolecules 2007, 40, 824-831.
823 Lenda, F.; Guenoun, F.; Martinez, J.; Lamaty, F. Synthesis of New Tetrazole and Triazole Substituted Pyroglutamic Acid and Proline Derivatives. Tetrahedron Lett. 2007, 48, 805-808.
822 Lee, T.; Cho, M.; Ko, S.-Y.; Youn, H.-J.; Baek, D. J.; Cho, W.-J.; Kang, C.-Y.; Kim, S. Synthesis and Evaluation of 1,2,3-Triazole Containing Analogues of the Immunostimulant α-GalCer. J. Med. Chem. 2007, 50, 585-589.
821 Lee, J. W.; Kim, J. H.; Kim, H. J.; Han, S. C.; Kim, J. H.; Shin, W. S.; Jin, S.-H. Synthesis of Symmetrical and Unsymmetrical PAMAM Dendrimers by Fusion between Azide- and Alkyne Functionalized PAMAM Dendrons. Bioconjugate Chem. 2007, 18, 579-584.
820 Lee, J. W.; Kim, J. H.; Han, S. C.; Kim, W. R.; Kim, B.-K.; Kim, J. H.; Huh, D.-S.; Shin, W. S.; Jin, S.-H. Synthesis of Diblock Codendrimers by Fusion of the Fréchet-Type and the PAMAM Dendrons. Macromol. Symp. 2007, 249/250, 357-364.
819 Lee, B. S.; Lee, J. K.; Kim, W.-J.; Jung, Y. H.; Sim, S. J.; Lee, J.; Choi, I. S. Surface-Initiated, Atom Transfer Radical Polymerization of Oligo(ethylene glycol) Methyl Ether Methacrylate and Subsequent Click Chemistry for Bioconjugation. Biomacromolecules 2007, 8, 744-749.
818 Le Droumaguet, B.; Mantovani, G.; Haddleton, D. M.; Velonia, K. Formation of Giant Amphiphiles by Post-Functionalization of Hydrophilic Protein-Polymer Conjugates. J. Mater. Chem. 2007, 17, 1916-1922.
817 Le Baut, N.; Diaz, D. D.; Punna, S.; Finn, M. G.; Brown, H. R. Study of High Glass Transition Temperature Thermosets Made from the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition Reaction. Polymer 2007, 48, 239-244.
816 Kumar, R.; El-Sagheer, A.; Tumpane, J.; Lincoln, P.; Wilhelmsson, L. M.; Brown, T. Template-Directed Oligonucleotide Strand Ligation, Covalent Intramolecular DNA Circularization and Catenation Using Click Chemistry. J. Am. Chem. Soc. 2007, 129, 6859-6864.
815 Kumar, I.; Rode, C. V. Efficient Synthesis of Fused 1,2,3-Triazolo-δ-Lactams using Huisgen [3 + 2] Dipolar Cycloaddition "Click-Chemistry" in Water. Chem. Lett. 2007, 36, 592-593.
814 Kuemin, M.; Sonntag, L.-S.; Wennemers, H. Azidoproline Containing Helices: Stabilization of the Polyproline II Structure by a Functionalizable Group. J. Am. Chem. Soc. 2007, 129, 466-467.
813 Kim, T.-D.; Shi, Z.; Luo, J.; Jang, S.-H.; Cheng, Y.-J.; Zhou, X.; Huang, S.; Dalton, L. R.; Herman, W.; Jen, A. K. Y. New Paradigm for Ultrahigh Electro-Optic Activity: Through Supramolecular Self-Assembly and Novel Lattice Hardening. Proc. SPIE-Int. Soc. Opt. Eng. 2007, 6470, 64700D/1-64700D/14.
812 Kim, S.; Cho, M.; Lee, T.; Lee, S.; Min, H.-Y.; Lee, S. K. Design, Synthesis, and Preliminary Biological Evaluation of a Novel Triazole Analogue of Ceramide. Bioorg. Med. Chem. Lett. 2007, 17, 4584-4587.
811 Ketola, J.; Katajisto, J.; Hakala, H.; Hovinen, J. Synthesis of Lanthanide(III) Chelates by Using 'Click' Chemistry. Helv. Chim. Acta 2007, 90, 607-615.
810 Kale, R. R.; Clancy, C. M.; Vermillion, R. M.; Johnson, E. A.; Iyer, S. S. Synthesis of Soluble Multivalent Glycoconjugates that Target the Hc Region of Botulinum Neurotoxin A. Bioorg. Med. Chem. Lett. 2007, 17, 2459-2464.
809 Kakuchi, R.; Toda, A.; Narumi, A.; Sakai, R.; Satoh, T.; Sugiyama, K.; Macosko, C. W.; Hirao, A.; Kakuchi, T. Precise Tuning of Thermoresponsive Property of Poly(N-isopropylacrylamide)s by Combination of ATRP "Click" Chemistry Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 344-345.
808 Johnson, J. A.; Finn, M. G.; Koberstein, J. T.; Turro, N. J. Synthesis of Photocleavable Linear Macromonomers by ATRP and Star Macromonomers by a Tandem ATRP-Click Reaction: Precursors to Photodegradable Model Networks. Macromolecules 2007, 40, 3589-3598.
807 Jim, C. K. W.; Qin, A.; Lam, J. W. Y.; Haeussler, M.; Tang, B. Z. Synthesis of Ferrocene-containing Polyacetylenes by Click Chemistry. J. Inorg. Organomet. Polym. Mater. 2007, 17, 289-293.
806 Jagadish, B.; Sankaranarayanan, R.; Xu, L.; Richards, R.; Vagner, J.; Hruby, V. J.; Gillies, R. J.; Mash, E. A. Squalene-Derived Flexible Linkers for Bioactive Peptides. Bioorg. Med. Chem. Lett. 2007, 17, 3310-3313.
805 Inverarity, I. A.; Hulme, A. N. Marked Small Molecule Libraries: a Truncated Approach to Molecular Probe Design. Org. Biomol. Chem. 2007, 5, 636-643.
804 Ikeda, M.; Hasegawa, T.; Numata, M.; Sugikawa, K.; Sakurai, K.; Fujiki, M.; Shinkai, S. Instantaneous Inclusion of a Polynucleotide and Hydrophobic Guest Molecules into a Helical Core of Cationic β-1,3-Glucan Polysaccharide. J. Am. Chem. Soc. 2007, 129, 3979-3988.
803 Hu, J.; Li, Y.; Ling, Y.; Yang, X.-l. Click Chemistry and its Applications in Drug Research Huaxue Shiji 2007, 29, 207-211,228.
802 Hsu, T.-L.; Hanson, S. R.; Kishikawa, K.; Wang, S.-K.; Sawa, M.; Wong, C.-H. Alkynyl Sugar Analogs for the Labeling and Visualization of Glycoconjugates in Cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 2614-2619.
801 Hoogenboom, R.; Moore, B. C.; Schubert, U. S. (Metallo)supramolecular Click Chemistry versus Click Chemistry in Polymer Science. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 685-686.
800 Homenick, C. M.; Lawson, G.; Adronov, A. Polymer Grafting of Carbon Nanotubes Using Living Free-Radical Polymerization. Polym. Rev. 2007, 47, 265-290.
799 Holland, J. P.; Aigbirhio, F. I.; Betts, H. M.; Bonnitcha, P. D.; Burke, P.; Christlieb, M.; Churchill, G. C.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Green, J. C.; Peach, J. M.; Vasudevan, S. R.; Warren, J. E. Functionalized Bis(thiosemicarbazonato) Complexes of Zinc and Copper: Synthetic Platforms Toward Site-Specific Radiopharmaceuticals. Inorg. Chem. 2007, 46, 465-485.
798 Hill, P. A.; Wei, Q.; Eckenhoff, R. G.; Dmochowski, I. J. Thermodynamics of Xenon Binding to Cryptophane in Water and Human Plasma. J. Am. Chem. Soc. 2007, 129, 9262-9263.
797 Hawker, C. J.; Fokin, V. V.; Finn, M. G.; Sharpless, K. B. Bringing Efficiency to Materials Synthesis: The Philosophy of Click Chemistry. Aust. J. Chem. 2007, 60, 381-383.
796 Haridas, V.; Lal, K.; Sharma, Y. K. Design and Synthesis of Triazole-Based Peptide Dendrimers. Tetrahedron Lett. 2007, 48, 4719-4722.
795 Guo, Z.; Lei, A.; Zhang, Y.; Xu, Q.; Xue, X.; Zhang, F.; Liang, X. "Click Saccharides": Novel Separation Materials for Hydrophilic Interaction Liquid Chromatography. Chem. Commun. 2007, 2491-2493.
794 Guo, M.; Galan, J.; Tao, W. A. A Novel Quantitative Proteomics Reagent Based on Soluble Nanopolymers. Chem. Commun. 2007, 1251-1253.
793 Gungor, E.; Cote, G.; Erdogan, T.; Durmaz, H.; Demirel, A. L.; Hizal, G.; Tunca, U. Heteroarm H-Shaped Terpolymers through Click Reaction. J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 1055-1065.
792 Grubbs, R. B. Roles of Polymer Ligands in Nanoparticle Stabilization. Polym. Rev. 2007, 47, 197-215.
791 Grotenbreg, G.; Ploegh, H. Chemical Biology: Dressed-up Proteins. Nature (London) 2007, 446, 993-995.
790 Gouin, S. G.; Kovensky, J. Direct Azidation of Unprotected Carbohydrates with PPh3/CBr4/NaN3. Modulation of the Degree of Substitution. Tetrahedron Lett. 2007, 48, 2875-2879.
789 Gouin, S. G.; Bultel, L.; Falentin, C.; Kovensky, J. A Simple Procedure for Connecting Two Carbohydrate Moieties by Click Chemistry Techniques. Eur. J. Org. Chem. 2007, 2007, 1160-1167.
788 Goodwin, A. P.; Lam, S. S.; Frechet, J. M. J. Rapid, Efficient Synthesis of Heterobifunctional Biodegradable Dendrimers. J. Am. Chem. Soc. 2007, 129, 6994-6995.
787 Gondi, S. R.; Vogt, A. P.; Sumerlin, B. S. Versatile Pathway to Functional Telechelics via RAFT Polymerization and Click Chemistry. Macromolecules 2007, 40, 474-481.
786 Goeminne, A.; McNaughton, M.; Bal, G.; Surpateanu, G.; Van der Veken, P.; De Prol, S.; Versees, W.; Steyaert, J.; Apers, S.; Haemers, A.; Augustyns, K. 1,2,3-Triazolylalkylribitol Derivatives as Nucleoside Hydrolase Inhibitors. Bioorg. Med. Chem. Lett. 2007, 17, 2523-2526.
785 Gmeiner, P. Laboratory Automation with Parallel Synthesis. A Solid Phase-Supported Access to New Biogenic Amine Receptor Ligands. GIT Labor-Fachzeitschrift 2007, 51, 290-292.
784 Glaser, M.; Aarstad, E. "Click Labeling" with 2-[18F]Fluoroethylazide for Positron Emission Tomography. Bioconjugate Chem. 2007, 18, 989-993.
783 Gissibl, A.; Padie, C.; Hager, M.; Jaroschik, F.; Rasappan, R.; Cuevas-Yanez, E.; Turrin, C.-O.; Caminade, A.-M.; Majoral, J.-P.; Reiser, O. Synthesis and Application of Phosphorus Dendrimer Immobilized Azabis(oxazolines). Org. Lett. 2007, 9, 2895-8.
782 Gil, M. V.; Arevalo, M. J.; Lopez, O. Click Chemistry - What's in a Name? Triazole Synthesis and Beyond. Synthesis 2007, 1589-1620.
781 Geng, J.; Mantovani, G.; Haddleton, D. M. Novel Synthesis of Neoglycopolymers by a Combination of "Click Chemistry" and Living Radical Polymerization. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 1046-1047.
780 Gao, H.; Matyjaszewski, K. Synthesis of Molecular Brushes by "Grafting onto" Method: Combination of ATRP and Click Reactions. J. Am. Chem. Soc. 2007, 129, 6633-6639.
779 Gallant, N. D.; Lavery, K. A.; Amis, E. J.; Becker, M. L. Universal Gradient Substrates for "Click" Biofunctionalization. Adv. Mater. 2007, 19, 965-969.
778 Gaillard, S.; Yakovlev, A.; Luccardini, C.; Oheim, M.; Feltz, A.; Mallet, J.-M. Synthesis and Characterization of a New Red-Emitting Ca2+ Indicator, Calcium Ruby. Org. Lett. 2007, 9, 2629-2632.
777 Fuwa, H.; Takahashi, Y.; Konno, Y.; Watanabe, N.; Miyashita, H.; Sasaki, M.; Natsugari, H.; Kan, T.; Fukuyama, T.; Tomita, T.; Iwatsubo, T. Divergent Synthesis of Multifunctional Molecular Probes to Elucidate the Enzyme Specificity of Dipeptidic ?-Secretase Inhibitors. ACS Chem. Biol. 2007, 2, 408-418.
776 Fukushima, K.; Vandenbos, A. J.; Fujiwara, T. Spiropyran Dimer Toward Photo-Switchable Molecular Machine. Chem. Mater. 2007, 19, 644-646.
775 Fujiwara, T.; Vandenbos, A. J.; Fukushima, K. Photoswitch Assembly of Dispiropyran-Polymer Conjugates. PMSE Prepr. 2007, 96, 788-789.
774 Froedin, M. A RSK Kinase Inhibitor Reporting its Selectivity. in vivo Nat. Chem. Biol. 2007, 3, 138-139.
773 Fringuelli, F.; Piermatti, O.; Pizzo, F.; Vaccaro, L. In Organic Reactions in Water 2007, p 146-184.
772 Fournier, D.; Hoogenboom, R.; Schubert, U. S. Clicking Polymers: a Straightforward Approach to Novel Macromolecular Architectures. Chem. Soc. Rev. 2007, 36, 1369-1380.
771 Fleischmann, S.; Komber, H.; Appelhans, D.; Voit, B. I. Synthesis of Functionalized NMP Initiators for Click Chemistry: a Versatile Method for the Preparation of Functionalized Polymers and Block Copolymers. Macromol. Chem. Phys. 2007, 208, 1050-1060.
770 Fischler, M.; Simon, U.; Nir, H.; Eichen, Y.; Burley, G. A.; Gierlich, J.; Gramlich, P. M. E.; Carell, T. Formation of Bimetallic Ag-Au Nanowires by Metallization of Artificial DNA Duplexes. Small 2007, 3, 1049-1055.
769 Figueira-Duarte, T. M.; Gegout, A.; Nierengarten, J.-F. Molecular and Supramolecular C60-Oligophenylenevinylene Conjugates. Chem. Commun. 2007, 109-119.
768 Feliu, L.; Vera-Luque, P.; Albericio, F.; Alvarez, M. Advances in Solid-Phase Cycloadditions for Heterocyclic Synthesis. J. Comb. Chem. 2007, 9, 521-565.
767 Evanoff, D. D., Jr.; Hayes, S. E.; Ying, Y.; Shim, G. H.; Lawrence, J. R.; Carroll, J. B.; Roeder, R. D.; Houchins, J. M.; Huebner, C. F.; Foulger, S. H. Functionalization of Poly(propargyl acrylate) Crystalline Colloidal Arrays through Click Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 163-164.
766 Ergin, M.; Kiskan, B.; Gacal, B.; Yagci, Y. Thermally Curable Polystyrene via Click Chemistry Macromolecules 2007, 40, 4724-4727.
765 Erberich, M.; Keul, H.; Moeller, M. Polyglycidols with Two Orthogonal Protective Groups: Preparation, Selective Deprotection, and Functionalization. Macromolecules 2007, 40, 3070-3079.
764 El-Batta, A.; Jiang, C.; Zhao, W.; Anness, R.; Cooksy, A. L.; Bergdahl, M. Wittig Reactions in Water Media Employing Stabilized Ylides with Aldehydes. Synthesis of α,β-Unsaturated Esters from Mixing Aldehydes, α-Bromoesters, and Ph3P in Aqueous NaHCO3. J. Org. Chem. 2007, 72, 5244-5259.
763 Durmaz, H.; Dag, A.; Altintas, O.; Erdogan, T.; Hizal, G.; Tunca, U. One-Pot Synthesis of ABC Type Triblock Copolymers via in situ Click [3 + 2] and Diels-Alder [4 + 2] Reactions. Macromolecules 2007, 40, 191-198.
762 Dondoni, A.; Marra, A. Addressing the Scope of the Azide-Nitrile Cycloaddition in Glycoconjugate Chemistry. The Assembly of C-Glycoclusters on a Calix[4]arene Scaffold through Tetrazole Spacers Tetrahedron 2007, 63, 6339-6345.
761 Dondoni, A. Triazole: the Keystone in Glycosylated Molecular Architectures Constructed by a Click Reaction. Chem.--Asian J. 2007, 2, 700-708.
760 Dolhem, F.; Johansson, M. J.; Antonsson, T.; Kann, N. Modular Synthesis of ChiraClick Ligands: A Library of P-Chirogenic Phosphines. J. Comb. Chem. 2007, 9, 477-486.
759 Disney, M. D.; Childs-Disney, J. L. Using Selection to Identify and Chemical Microarray to Study the RNA Internal Loops Recognized by 6'-N-Acylated Kanamycin A. ChemBioChem 2007, 8, 649-656.
758 Dijkgraaf, I.; Rijnders, A. Y.; Soede, A.; Dechesne, A. C.; van Esse, G. W.; Brouwer, A. J.; Corstens, F. H. M.; Boerman, O. C.; Rijkers, D. T. S.; Liskamp, R. M. J. Synthesis of DOTA-Conjugated Multivalent Cyclic-RGD Peptide Dendrimers via 1,3-Dipolar Cycloaddition and their Biological Evaluation: Implications for Tumor Targeting and Tumor Imaging Purposes. Org. Biomol. Chem. 2007, 5, 935-944.
757 Dieterich Daniela, C.; Lee Jennifer, J.; Link, A. J.; Graumann, J.; Tirrell David, A.; Schuman Erin, M. Labeling, Detection and Identification of Newly Synthesized Proteomes with Bioorthogonal Non-Canonical Amino-Acid Tagging. Nat. Protoc. 2007, 2, 532-40.
756 Diaz, D. D.; M. g, F.; Fokin, V. V., Stabilization of Organogels and Hydrogels by Azide-Alkyne[2+3] Cycloaddition, 2006-US33016, 2007027493, 20060823.
755 Devadoss, A.; Chidsey, C. E. D. Azide-Modified Graphitic Surfaces for Covalent Attachment of Alkyne-Terminated Molecules by "Click" Chemistry. J. Am. Chem. Soc. 2007, 129, 5370-5371.
754 Deng, G.; Ma, D.; Xu, Z. Synthesis of ABC-Type Miktoarm Star Polymers by "Click" Chemistry, ATRP and ROP. Eur. Polym. J. 2007, 43, 1179-1187.
753 Delapierre, G.; Duclairoir, F.; Marchon, J.-C., Method for Grafting Molecules of Interest on Inorganic Silicon Surfaces, Resulting Surfaces and Uses Thereof, 2006-FR2395, 2007048924, 20061025.
752 Deguise, I.; Lagnoux, D.; Roy, R. Synthesis of Glycodendrimers Containing both Fucoside and Galactoside Residues and Their Binding Properties to Pa-IL and PA-IIL Lectins from Pseudomonas aeruginosa. New J. Chem. 2007, 31, 1321-1331.
751 Dedola, S.; Nepogodiev, S. A.; Field, R. A. Recent applications of the CuI-catalyzed Huisgen azide-alkyne 1,3-dipolar cycloaddition reaction in carbohydrate chemistry. Org. Biomol. Chem. 2007, 5, 1006-1017.
750 Decreau, R. A.; Collman, J. P.; Yang, Y.; Yan, Y.; Devaraj, N. K. Syntheses of Hemoprotein Models that can be Covalently Attached onto Electrode Surfaces by Click Chemistry. J. Org. Chem. 2007, 72, 2794-2802.
749 Dabiri, M.; Salehi, P.; Baghbanzadeh, M.; Zolfigol, M. A.; Bahramnejad, M. Silica Sulfuric Acid. An Efficient and Versatile Acidic Catalyst for the Rapid and Ecofriendly Synthesis of 1,3,4-Oxadiazoles at Ambient Temperature. Synth. Commun. 2007, 37, 1201-1209.
748 Crescenzi, V.; Cornelio, L.; Di Meo, C.; Nardecchia, S.; Lamanna, R. Novel Hydrogels via Click Chemistry: Synthesis and Potential Biomedical Applications. Biomacromolecules 2007, 8, 1844-1850.
747 Cooper, B. M.; Parrish, B.; Emrick, T. Novel Polymer-Drug Conjugates. PMSE Prepr. 2007, 96, 328.
746 Constable, D. J. C.; Dunn, P. J.; Hayler, J. D.; Humphrey, G. R.; Leazer, J. L., Jr.; Linderman, R. J.; Lorenz, K.; Manley, J.; Pearlman, B. A.; Wells, A.; Zaks, A.; Zhang, T. Y. Key Green Chemistry Research Areas-a Perspective from Pharmaceutical Manufacturers. Green Chem. 2007, 9, 411-420.
745 Connor, R. E.; Tirrell, D. A. Non-Canonical Amino Acids in Protein Polymer Design. Polym. Rev. 2007, 47, 9-28.
744 Collman, J. P.; Yang, Y.; Decreau, R. A. Synthesis of Nitric Oxide Reductase Active Site Models Bearing Key Components at Both Distal and Proximal Sites. Org. Lett. 2007, 9, 2855-2858.
743 Collman, J. P.; Devaraj, N. K.; Decreau, R. A.; Yang, Y.; Yan, Y.-L.; Ebina, W.; Eberspacher, T. A.; Chidsey, C. E. D. A Cytochrome c Oxidase Model Catalyzes Oxygen to Water Reduction Under Rate-Limiting Electron Flux. Science (Washington, DC, U. S.) 2007, 315, 1565-1568.
742 Cohen, M. S.; Hadjivassiliou, H.; Taunton, J. A Clickable Inhibitor Reveals Context-dependent Autoactivation of p90 RSK. Nat. Chem. Biol. 2007, 3, 156-160.
741 Chuprakov, S.; Chernyak, N.; Dudnik, A. S.; Gevorgyan, V. Direct Pd-Catalyzed Arylation of 1,2,3-Triazoles. Org. Lett. 2007, 9, 2333-2336.
740 Cheng, Y.; Liu, M.-F.; Fang, D.-C.; Lei, X.-M. Substrate-controlled and Site-selective [3 + 2] Cycloadditions of N-heterocyclic Carbene Derived Ambident Dipoles. Chem.--Eur. J. 2007, 13, 4282-4292.
739 Cheng, L.; Chen, Q.; Liu, J.; Du, Y. Synthesis of a Fluorescence-labeled K30 Antigen Repeating Unit Using Click Chemistry. Carbohydr. Res. 2007, 342, 975-981.
738 Chen, W.; Gilson, M. K. ConCept: de Novo Design of Synthetic Receptors for Targeted Ligands. J. Chem. Inf. Model. 2007, 47, 425-434.
737 Chen, J.; Nikolovska-Coleska, Z.; Yang, C.-Y.; Gomez, C.; Gao, W.; Krajewski, K.; Jiang, S.; Roller, P.; Wang, S. Design and Synthesis of a New, Conformationally Constrained, Macrocyclic Small-molecule Inhibitor of STAT3 via Click Chemistry. Bioorg. Med. Chem. Lett. 2007, 17, 3939-3942.
736 Chen, H.; Taylor, J. L.; Abrams, S. R. Design and Synthesis of ▀-Methoxyacrylate Analogues via Click Chemistry and Biological Evaluations. Bioorg. Med. Chem. Lett. 2007, 17, 1979-1983.
735 Chen, G.; Tao, L.; Mantovani, G.; Ladmiral, V.; Burt, D. P.; Macpherson, J. V.; Haddleton, D. M. Synthesis of Azide/Alkyne-Terminal Polymers and Application for Surface Functionalisation through a [2 + 3] Huisgen Cycloaddition Process, "Click Chemistry". Soft Matter 2007, 3, 732-739.
734 Chassaing, S.; Kumarraja, M.; Sido, A. S. S.; Pale, P.; Sommer, J. Click Chemistry in CuI -zeolites: The Huisgen [3 + 2]-Cycloaddition. Org. Lett. 2007, 9, 883-886.
733 Chang, P. V.; Prescher, J. A.; Hangauer, M. J.; Bertozzi, C. R. Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters. J. Am. Chem. Soc. 2007, 129, 8400-8401.
732 Chandrasekhar, V.; Thilagar, P.; Krishnan, V.; Bickley, J. F.; Steiner, A. Click Synthesis of Fluorine-Rich Cyclotriphosphazene Hydrazones. Synthesis and Supramolecular Structures of N3P3(N(Me)N=CHC6F5)6, spiro-N3P3(C12H8O2)(N(Me)N=CHC6F5)4, and dispiro-N3P3(C12H8O2)2(N(Me)N=CHC6F5)2. Crystal Growth & Design 2007, 7, 668-675.
731 Cauet, S.; Mantovani, G.; Ladmiral, V.; Haddleton, D. M. Biotin End-Functional Star Polymers via TMM LRP and Click Chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 1003-1004.
730 Castro, S.; Cherney, E. C.; Snyder, N. L.; Peczuh, M. W. Synthesis of Substituted Septanosyl-1,2,3-Triazoles. Carbohydr. Res. 2007, 342, 1366-1372.
729 Castagnolo, D.; Dessi, F.; Radi, M.; Botta, M. Synthesis of Enantiomerically Pure α-[4-(1-Substituted)-1,2,3-triazol-4-yl]-benzylacetamides via Microwave-Assisted Click Chemistry: Towards New Potential Antimicrobial Agents. Tetrahedron: Asymmetry 2007, 18, 1345-1350.
728 Brown, A. H.; Downing, D. O.; Sheares, V. V. Click Functionalization of Aliphatic Polyesters. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 368-369.
727 Braunschweig, A. B.; Dichtel, W. R.; Miljanic, O. S.; Olson, M. A.; Spruell, J. M.; Khan, S. I.; Heath, J. R.; Stoddart, J. F. Modular Synthesis and Dynamics of a Variety of Donor-acceptor Interlocked Compounds Prepared by Click Chemistry. Chem.--Asian J. 2007, 2, 634-647.
726 Boutevin, B.; David, G.; Boyer, C. Telechelic Oligomers and Macromonomers by Radical Techniques. Adv. Polym. Sci. 2007, 206, 31-135.
725 Boshoff, H. I.; Dowd, C. S. Chemical Genetics: an Evolving Toolbox for Target Identification and Lead Optimization. Prog. Drug Res. 2007, 64, 49-77.
724 Bosch, L.; Vilarrasa, J. Cu2(OTf)2-catalyzed and Microwave-controlled Preparation of Tetrazoles from Nitriles and Organic Azides under Mild, Safe Conditions. Angew. Chem., Int. Ed. 2007, 46, 3926-3930.
723 Bodnar, B. S.; Miller, M. J. Reactions of Nitroso Hetero-Diels-Alder Cycloadducts with Azides: Stereoselective Formation of Triazolines and Aziridines. J. Org. Chem. 2007, 72, 3929-3932.
722 Bock, V. D.; Speijer, D.; Hiemstra, H.; van Maarseveen, J. H. 1,2,3-Triazoles as Peptide Bond Isosteres: Synthesis and Biological Evaluation of Cyclotetrapeptide Mimics. Org. Biomol. Chem. 2007, 5, 971-975.
721 Bisol, T. B.; Sa, M. M. Recent Advances in the Preparation of Aziridine. Their Applications in Synthesis and Mechanistic Implications. Quim. Nova 2007, 30, 106-115.
720 Binder, W. H.; Sachsenhofer, R.; Straif, C. J.; Zirbs, R. Surface-modified Nanoparticles via Thermal and Cu(I)-Mediated "Click" Chemistry: Generation of luminescent CdSe Nanoparticles with Polar Ligands Guiding Supramolecular Recognition. J. Mater. Chem. 2007, 17, 2125-2132.
719 Binder, W. H.; Sachsenhofer, R. 'Click' Chemistry in Polymer and Materials Science. Macromol. Rapid Commun. 2007, 28, 15-54.
718 Binder, W. H.; Petraru, L.; Roth, T.; Groh, P. W.; Palfi, V.; Keki, S.; Ivan, B. Magnetic and Temperature-sensitive Release Gels from Supramolecular Polymers. Adv. Funct. Mater. 2007, 17, 1317-1326.
717 Binder, W. H.; Gloger, D.; Weinstabl, H.; Allmaier, G.; Pittenauer, E. Telechelic Poly(N-isopropylacrylamides) via Nitroxide-Mediated Controlled Polymerization and "Click" Chemistry: Livingness and "Grafting-from" Methodology. Macromolecules 2007, 40, 3097-3107.
716 Bertrand, P.; Gesson, J. P. Click Chemistry with O-Dimethylpropargylcarbamate for Preparation of pH-Sensitive Functional Groups. A Case Study. J. Org. Chem. 2007, 72, 3596-3599.
715 Bergbreiter, D. E.; Chance, B. S. "Click"-Based Covalent Layer-by-Layer Assembly on Polyethylene Using Water-Soluble Polymeric Reagents. Macromolecules 2007, 40, 5337-5343.
714 Beckmann, H. S. G.; Wittmann, V. One-Pot Procedure for Diazo Transfer and Azide-Alkyne Cycloaddition: Triazole Linkages from Amines. Org. Lett. 2007, 9, 1-4.
713 Becker, M. L.; Gallant, N. D.; Lavery, K. A.; Amis, E. J. Combinatorial Methods for Tissue Engineering. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2007, 48, 153-154.
712 Batchu, V. R.; Barange, D. K.; Kumar, D.; Sreekanth, B. R.; Vyas, K.; Reddy, E. A.; Pal, M. Tandem C-C Coupling - Intramolecular Acetylenic Schmidt Reaction under Pd/C-Cu Catalysis. Chem. Commun. 2007, 1966-1968.
711 Bastero, A.; Font, D.; Pericas, M. A. Assessing the Suitability of 1,2,3-Triazole Linkers for Covalent Immobilization of Chiral Ligands: Application to Enantioselective Phenylation of Aldehydes. J. Org. Chem. 2007, 72, 2460-2468.
710 Basak, A.; Chandra, K.; Pal, R.; Ghosh, S. C. Kinugasa Reaction under Click Chemistry Conditions. Synlett 2007, 1585-1588.
709 Barrett, E. S.; Dale, T. J.; Rebek, J., Jr. Assembly and Exchange of Resorcinarene Capsules Monitored by Fluorescence Resonance Energy Transfer. J. Am. Chem. Soc. 2007, 129, 3818-3819.
708 Barral, K.; Moorhouse, A. D.; Moses, J. E. Efficient Conversion of Aromatic Amines into Azides: a One-pot Synthesis of Triazole Linkages. Org. Lett. 2007, 9, 1809-1811.
707 Barner, L.; Davis, T. P.; Stenzel, M. H.; Barner-Kowollik, C. Complex Macromolecular Architectures by Reversible Addition Fragmentation Chain Transfer Chemistry: Theory and Practice. Macromol. Rapid Commun. 2007, 28, 539-559.
706 Ball, P. The Click Concept Chem. World 2007, 4, 46-48,50-51.
705 Aprahamian, I.; Yasuda, T.; Ikeda, T.; Saha, S.; Dichtel, W. R.; Isoda, K.; Kato, T.; Stoddart, J. F. A Liquid-Crystalline Bistable [2]Rotaxane. Angew. Chem., Int. Ed. 2007, 46, 4675-4679.
704 Aprahamian, I.; Dichtel, W. R.; Ikeda, T.; Heath, J. R.; Stoddart, J. F. A Clicked Bistable [2]Rotaxane. Org. Lett. 2007, 9, 1287-1290.
703 Antoni, P.; Nystroem, D.; Hawker, C. J.; Hult, A.; Malkoch, M. A Chemoselective Approach for the Accelerated Synthesis of Well-defined Dendritic Architectures. Chem. Commun. 2007, 2249-2251.
702 Angell, Y.; Burgess, K. Base Dependence in Copper-catalyzed Huisgen Reactions: Efficient Formation of Bistriazoles. Angew. Chem., Int. Ed. 2007, 46, 3649-3651.
701 Amir, R. J.; Danieli, E.; Shabat, D. Receiver-Amplifier, Self-Immolative Dendritic Device. Chem.--Eur. J. 2007, 13, 812-821.
700 Albertin, G.; Antoniutti, S.; Bacchi, A.; Celebrin, A.; Pelizzi, G.; Zanardo, G. Reactions of Manganese and Rhenium Complexes with Organic Azides: Preparation of Tetraazabutadiene Derivatives. Dalton Trans. 2007, 661-668.
699 Alajarin, M.; Cabrera, J.; Pastor, A.; Villalgordo, J. M. A New Modular and Flexible Approach to [1,2,3]Triazolo[1,5-a][1,4]benzodiazepines. Tetrahedron Lett. 2007, 48, 3495-3499.
698 Agut, W.; Taton, D.; Lecommandoux, S. A Versatile Synthetic Approach to Polypeptide Based Rod-Coil Block Copolymers by Click Chemistry. Macromolecules 2007, 40, 5653-5661.
697 Adamo, M. F. A.; Duffy, E. F.; Donati, D.; Sarti-Fantoni, P. Modular Synthesis of Isoxazolopyridones and Pyrazolopyridones. Tetrahedron 2007, 63, 2047-2052.
696 Zou, W. Q.; Li, Y.; Zheng, F. K.; Guo, G. C.; Huang, J. S., Dimethyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)benzene-1,3-dicarboxylate. Acta Crystallogr., Sect. E: Struct. Rep. Online 2006, E62, (8), o3591-o3593.
695 Zinzalla, G.; Milroy, L.-G.; Ley, S. V., Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives. Org. Biomol. Chem. 2006, 4, (10), 1977-2002.
694 Zhu, Y.; Huang, Y.; Meng, W.-D.; Li, H.; Qing, F.-L., Novel perfluorocyclobutyl (PFCB)-containing polymers formed by click chemistry. Polymer 2006, 47, (18), 6272-6279.
693 Zhu, L.; Anslyn, E. V., Signal amplification by allosteric catalysis. Angew. Chem., Int. Ed. 2006, 45, (8), 1190-1196.
692 Zhou, Z.; Li, S.; Zhang, Y.; Liu, M., 1H-1,2,3-triazole based polymer materials for proton exchange membranes. PMSE Prepr. 2006, 94, 609.
691 Zhou, L.; Thakur, C. S.; Molinaro, R. J.; Paranjape, J. M.; Hoppes, R.; Jeang, K.-T.; Silverman, R. H.; Torrence, P. F., Delivery of 2-5A cargo into living cells using the Tat cell penetrating peptide: 2-5A-tat. Bioorg. Med. Chem. 2006, 14, (23), 7862-7874.
690 Zhong, Y.-W.; Matsuo, Y.; Nakamura, E., Convergent Synthesis of a Polyfunctionalized Fullerene by Regioselective Five-Fold Addition of a Functionalized Organocopper Reagent to C60. Org. Lett. 2006, 8, (7), 1463-1466.
689 Zheng, S.-L.; Reid, S.; Lin, N.; Wang, B., Microwave-assisted synthesis of ethynylarylboronates for the construction of boronic acid-based fluorescent sensors for carbohydrates. Tetrahedron Lett. 2006, 47, (14), 2331-2335.
688 Zhao, Y.-B.; Yan, Z.-Y.; Liang, Y.-M., Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles in ionic liquid/water system. Tetrahedron Lett. 2006, 47, (10), 1545-1549.
687 Zhao, X. Z.; Semenova, E. A.; Liao, C.; Nicklaus, M.; Pommier, Y.; Burke, T. R., Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands. Bioorg. Med. Chem. 2006, 14, (23), 7816-7825.
686 Zhang, Z.; Fan, E., Solid phase synthesis of peptidotriazoles with multiple cycles of triazole formation. Tetrahedron Lett. 2006, 47, (5), 665-669.
685 Zhang, Y.; Luo, S.; Tang, Y.; Yu, L.; Hou, K.-Y.; Cheng, J.-P.; Zeng, X.; Wang, P. G., Carbohydrate-Protein Interactions by "Clicked" Carbohydrate Self-Assembled Monolayers. Anal. Chem. 2006, 78, (6), 2001-2008.
684 Zhang, X. R.; Xu, M. H.; Li, X. M.; Zhang, S. S., Ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetate. Acta Crystallogr., Sect. E: Struct. Rep. Online 2006, E62, (8), o3278-o3279.
683 Zhang, X.; Hsung, R. P.; You, L., Tandem azidination- and hydroazidination-Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles. Org. Biomol. Chem. 2006, 4, (14), 2679-2682.
682 Zhang, X. Clickphosphines for transition metal-catalyzed reactions. 2006-US21518 2006130842, 20060602., 2006.
681 Zhang, H.; Piacham, T.; Drew, M.; Patek, M.; Mosbach, K.; Ye, L., Molecularly Imprinted Nanoreactors for Regioselective Huisgen 1,3-Dipolar Cycloaddition Reaction. J. Am. Chem. Soc. 2006, 128, (13), 4178-4179.
680 Zhang, G.; Fang, L.; Zhu, L.; Sun, D.; Wang Peng, G., Syntheses and biological activity of bisdaunorubicins. Bioorg. Med. Chem. 2006, 14, (2), 426-34.
679 Yu, H.; Huang, S.; Chokhawala, H.; Sun, M.; Zheng, H.; Chen, X., Highly efficient chemoenzymatic synthesis of naturally occurring and non-natural α-2,6-linked sialosides: A P. damsela α-2,6-sialyltransferase with extremely flexible donor-substrate specificity. Angew. Chem., Int. Ed. 2006, 45, (24), 3938-3944.
678 Yoo, E. J.; Bae, I.; Cho, S. H.; Han, H.; Chang, S., A Facile Access to N-Sulfonylimidates and Their Synthetic Utility for the Transformation to Amidines and Amides. Org. Lett. 2006, 8, (7), 1347-1350.
677 Yilmaz, M. D.; Bozdemir, O. A.; Akkaya, E. U., Light Harvesting and Efficient Energy Transfer in a Boron-dipyrrin (BODIPY) Functionalized Perylenediimide Derivative. Org. Lett. 2006, 8, (13), 2871-2873.
676 Yap, A. H.; Weinreb, S. M., β-Tosylethylazide. A useful synthon for preparation of N-protected 1,2,3-triazoles via click chemistry. Tetrahedron Lett. 2006, 47, (18), 3035-3038.
675 Yagci, Y.; Tasdelen, M. A., Mechanistic transformations involving living and controlled/living polymerization methods. Prog. Polym. Sci. 2006, 31, (12), 1133-1170.
674 Xu, Y.-J.; Zhang, Y.-F.; Li, J.-Q., Predicting Facile Epoxidation of the Diamond (100) Surface by Dioxiranes and Subsequent Ring-Opening Reactions with Nucleophiles. J. Chem. Phys. B 2006, 110, (12), 6148-6153.
673 Xu, J.; DeGraw, A. J.; Duckworth, B. P.; Lenevich, S.; Tann, C.-M.; Jenson, E. C.; Gruber, S. J.; Barany, G.; Distefano, M. D., Synthesis and reactivity of 6,7-dihydrogeranylazides: reagents for primary azide incorporation into peptides and subsequent Staudinger ligation. Chem. Biol. Drug Des. 2006, 68, (2), 85-96.
672 Xu, C. Y.; Huang, M. Z., An approach to new water-soluble oligo(ethylene glycol) camptothecin analogues by 1,3-dipolar cycloaddition. Chin. Chem. Lett. 2006, 17, (7), 883-886.
671 Xia, Y.; Fan, Z.; Yao, J.; Liao, Q.; Li, W.; Qu, F.; Peng, L., Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus. Bioorg. Med. Chem. Lett. 2006, 16, (10), 2693-2698.
670 Wu, Y.-M.; Deng, J.; Chen, Q.-Y., Studies on new strategies for the synthesis of oligomeric 1,2,3-triazoles. Synlett 2006, (4), 645-647.
669 Wilkinson, B. L.; Bornaghi, L. F.; Poulsen, S.-A.; Houston, T. A., Synthetic utility of glycosyl triazoles in carbohydrate chemistry. Tetrahedron 2006, 62, (34), 8115-8125.
668 Wilkinson, B. L.; Bornaghi, L. F.; Houston, T. A.; Poulsen, S. A.; White, A. R., 4-Hydroxymethyl-1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,2,3-triazole. Acta Crystallogr., Sect. E: Struct. Rep. Online 2006, E62, (11), o5065-o5067.
667 Wilkinson, B. L.; Bornaghi, L. F.; Houston, T. A.; Innocenti, A.; Supuran, C. T.; Poulsen, S.-A., A Novel Class of Carbonic Anhydrase Inhibitors: Glycoconjugate Benzene Sulfonamides Prepared by "Click-Tailing". J. Med. Chem. 2006, 49, (22), 6539-6548.
666 Whittaker, M. R.; Urbani, C. N.; Monteiro, M. J., Synthesis of 3-miktoarm stars and 1st generation mikto dendritic copolymers by "living" radical polymerization and "click" chemistry. J. Am. Chem. Soc. 2006, 128, (35), 11360-1.
665 Whiting, M.; Muldoon, J.; Lin, Y.-C.; Silverman, S. M.; Lindstrom, W.; Olson, A. J.; Kolb, H. C.; Finn, M. G.; Sharpless, K. B.; Elder, J. H.; Fokin, V. V., Inhibitors of HIV-1 protease by using in situ click chemistry. Angew. Chem., Int. Ed. 2006, 45, (9), 1435-1439.
664 Whiting, M.; Fokin, V. V., Copper-catalyzed reaction cascade: direct conversion of alkynes into N-sulfonylazetidin-2-imines. Angew. Chem., Int. Ed. 2006, 45, (19), 3157-3161.
663 White, M. A.; Johnson, J. A.; Koberstein, J. T.; Turro, N. J., Toward the Syntheses of Universal Ligands for Metal Oxide Surfaces: Controlling Surface Functionality through Click Chemistry. J. Am. Chem. Soc. 2006, 128, (35), 11356-11357.
662 Weterings, J. J.; Khan, S.; Van der Heden, G. J.; Drijfhout, J. W.; Melief, C. J. M.; Overkleeft, H. S.; Van der Burg, S. H.; Ossendorp, F.; Van der Marel, G. A.; Filippov, D. V., Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: Towards synthetic epitope-based vaccines. Bioorg. Med. Chem. Lett. 2006, 16, (12), 3258-3261.
661 Weissleder, R., Molecular Imaging in Cancer. Science (Washington, DC, U. S.) 2006, 312, (5777), 1168-1171.
660 Wei, Q.; Seward, G. K.; Hill, P. A.; Patton, B.; Dimitrov, I. E.; Kuzma, N. N.; Dmochowski, I. J., Designing 129Xe NMR Biosensors for Matrix Metalloproteinase Detection. J. Am. Chem. Soc. 2006, 128, (40), 13274-13283.
659 Waser, J.; Gaspar, B.; Nambu, H.; Carreira, E. M., Hydrazines and Azides via the Metal-Catalyzed Hydrohydrazination and Hydroazidation of Olefins. J. Am. Chem. Soc. 2006, 128, (35), 11693-11712.
658 Wang, X.-Y.; Kimyonok, A.; Weck, M., Functionalization of polymers with phosphorescent iridium complexes via click chemistry. Chem. Commun. 2006, (37), 3933-3935.
657 Wang, J.; Uttamchandani, M.; Li, J.; Hu, M.; Yao, S. Q., Rapid Assembly of Matrix Metalloprotease Inhibitors Using Click Chemistry. Org. Lett. 2006, 8, (17), 3821-3824.
656 Wang, J.; Uttamchandani, M.; Li, J.; Hu, M.; Yao Shao, Q., "Click" synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases. Chem. Commun. 2006, (36), 3783-5.
655 Wang, J.; Sui, G.; Mocharla, V. P.; Lin, R. J.; Phelps, M. E.; Kolb, H. C.; Tseng, H.-R., Integrated microfluidics for parallel screening of an in situ click chemistry library. Angew. Chem., Int. Ed. 2006, 45, (32), 5276-5281.
654 Wan, Q.; Chen, J.; Chen, G.; Danishefsky, S. J., A Potentially Valuable Advance in the Synthesis of Carbohydrate-Based Anticancer Vaccines through Extended Cycloaddition Chemistry. J. Org. Chem. 2006, 71, (21), 8244-8249.
653 Vogt, P. K.; Bader, A. G.; Kang, S., Phosphoinositide 3-kinase: From viral oncoprotein to drug target. Virology 2006, 344, (1), 131-138.
652 Vogt, A. P.; Sumerlin, B. S., An Efficient Route to Macromonomers via ATRP and Click Chemistry. Macromolecules 2006, 39, (16), 5286-5292.
651 Viguier, R. F. H.; Hulme, A. N., A Sensitized Europium Complex Generated by Micromolar Concentrations of Copper(I): Toward the Detection of Copper(I) in Biology. J. Am. Chem. Soc. 2006, 128, (35), 11370-11371.
650 Vestberg, R.; Malkoch, M.; Kade, M.; Wu, P.; Fokin, V. V.; Sharpless, K. B.; Hawker, C. J., Layer-by-layer deposition of dendrimers using click-chemistry. PMSE Prepr. 2006, 94, 256-257.
649 Vestberg, R.; Malkoch, M.; Gupta, N.; Hawker, C. J., Synthesis of hydrogels with well defined network structure using click chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 190-191.
648 van der Peet, P.; Gannon, C. T.; Walker, I.; Dinev, Z.; Angelin, M.; Tam, S.; Ralton, J. E.; McConville, M. J.; Williams, S. J., Use of click chemistry to define the substrate specificity of Leishmania β-1,2-mannosyltransferases. ChemBioChem 2006, 7, (9), 1384-1391.
647 Uozumi, Y.; Suzuka, T.; Kawade, R.; Takenaka, H., pi-allylic azidation in water with an amphiphilic resin-supported palladium-phosphine complex. Synlett 2006, (13), 2109-2113.
646 Tsarevsky, N. V.; Matyjaszewski, K., Controlled synthesis of polymers with ionic or ionizable groups using atom transfer radical polymerization. ACS Symp. Ser. 2006, 937, (Polyelectrolytes and Polyzwitterions), 79-94.
645 Tron, G. C.; Pirali, T.; Sorba, G.; Pagliai, F.; Busacca, S.; Genazzani, A. A., Medicinal chemistry of Combretastatin A4: Present and future directions. J. Med. Chem. 2006, 49, (11), 3033-3044.
644 Thomsen, A. D.; Malmstrom, E.; Hvilsted, S., Novel polymers with a high carboxylic acid loading. J. Polym. Sci., Part A: Polym. Chem. 2006, 44, (21), 6360-6377.
643 Thibault, R. J.; Takizawa, K.; Lowenheilm, P.; Helms, B.; Mynar, J. L.; Frechet, J. M. J.; Hawker, C. J., A Versatile New Monomer Family: Functionalized 4-Vinyl-1,2,3-Triazoles via Click Chemistry. J. Am. Chem. Soc. 2006, 128, (37), 12084-12085.
642 Thibault, R. J.; Takizawa, K.; Helms, B.; Mynar, J. L.; Lowenhielm, P.; Frechet, J. M. J.; Hawker, C. J., Synthesis of triazole-based vinyl monomers. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (1), 349.
641 Ten Brink, H. T.; Meijer, J. T.; Geel, R. V.; Damen, M.; Loewik, D. W. P. M.; Van Hest, J. C. M., Solid-phase synthesis of C-terminally modified peptides. J. Peptide Sci. 2006, 12, (11), 686-692.
640 Temelkoff, D. P.; Zeller, M.; Norris, P., N-Glycoside neoglycotrimers from 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl azide. Carbohydr. Res. 2006, 341, (9), 1081-1090.
639 Takaoka, Y.; Tsutsumi, H.; Kasagi, N.; Nakata, E.; Hamachi, I., One-Pot and Sequential Organic Chemistry on an Enzyme Surface to Tether a Fluorescent Probe at the Proximity of the Active Site with Restoring Enzyme Activity. J. Am. Chem. Soc. 2006, 128, (10), 3273-3280.
638 Sun, X.-L.; Stabler, C. L.; Cazalis, C. S.; Chaikof, E. L., Carbohydrate and Protein Immobilization onto Solid Surfaces by Sequential Diels-Alder and Azide-Alkyne Cycloadditions. Bioconjugate Chem. 2006, 17, (1), 52-57.
637 Sun Eric, Y.; Josephson, L.; Weissleder, R., "Clickable" nanoparticles for targeted imaging. Mol. Imaging 2006, 5, (2), 122-8.
636 Sumerlin, B. S.; Vogt, A. P., Macromonomer synthesis via ATRP and click chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 549-550.
635 Such, G. K.; Quinn, J. F.; Quinn, A.; Tjipto, E.; Caruso, F., Assembly of Ultrathin Polymer Multilayer Films by Click Chemistry. J. Am. Chem. Soc. 2006, 128, (29), 9318-9319.
634 Streuff, J.; Nieger, M.; Muniz, K., Synthesis of small tripeptide molecules through a catalysis sequence comprising metathesis and aminohydroxylation. Chem.--Eur. J. 2006, 12, (16), 4362-4371.
633 Srinivasan, R.; Uttamchandani, M.; Yao, S. Q., Rapid Assembly and in Situ Screening of Bidentate Inhibitors of Protein Tyrosine Phosphatases. Org. Lett. 2006, 8, (4), 713-716.
632 Srinivasachari, S.; Zhang, G.; Liu, Y.; Reineke, T. M., Novel "click" glycopolymers containing 1,2,3-triazole linkers for DNA delivery. PMSE Prepr. 2006, 94, 180-181.
631 Srinivasachari, S.; Liu, Y.; Zhang, G.; Prevette, L.; Reineke, T. M., Trehalose Click Polymers Inhibit Nanoparticle Aggregation and Promote pDNA Delivery in Serum. J. Am. Chem. Soc. 2006, 128, (25), 8176-8184.
630 Sonntag, L.-S.; Schweizer, S.; Ochsenfeld, C.; Wennemers, H., The "Azido Gauche Effect"-Implications for the Conformation of Azidoprolines. J. Am. Chem. Soc. 2006, 128, (45), 14697-14703.
629 Sohma, Y.; Taniguchi, A.; Kimura, M.; Chiyomori, Y.; Fukao, F.; Okada, T.; Ikeda, K.; Hayashi, Y.; Kimura, T.; Hirota, S.; Matsuzaki, K.; Kiso, Y., "Click peptide" based on the "Q-acyl isopeptide method": development of chemical biology-oriented Alzheimer's disease-related Ab1-42 analogues. Peptide Science 2006, 42nd, 25-28.
628 Sohma, Y.; Kiso, Y., "Click peptides"-chemical biology-oriented synthesis of Alzheimer's disease-related amyloid β peptide (Aβ) analogues based on the "O-acyl isopeptide method". ChemBioChem 2006, 7, (10), 1549-1557.
627 Smith, C. D.; Tchabanenko, K.; Adlington, R. M.; Baldwin, J. E., Synthesis of linked heterocycles via use of bis-acetylenic compounds. Tetrahedron Lett. 2006, 47, (19), 3209-3212.
626 Slater, M.; Snauko, M.; Svec, F.; Frechet, J. M. J., "Click Chemistry" in the Preparation of Porous Polymer-Based Particulate Stationary Phases for m-HPLC Separation of Peptides and Proteins. Anal. Chem. 2006, 78, (14), 4969-4975.
625 Seela, F.; Sirivolu, V. R., DNA containing side chains with terminal triple bonds: base-pair stability and functionalization of alkynylated pyrimidines and 7-deazapurines. Chem. Biodiversity 2006, 3, (5), 509-514.
624 Sawa, M.; Hsu, T.-L.; Itoh, T.; Sugiyama, M.; Hanson Sarah, R.; Vogt Peter, K.; Wong, C.-H., Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, (33), 12371-6.
623 Sato, H.; Miura, Y.; Yamauchi, T.; Kobayashi, K.; Saito, N.; Takai, O., Carbohydrate microarrays by click chemistry. Trans. Mat. Res. Soc. Jap. 2006, 31, (3), 659-662.
622 Sanki, A. K.; Mahal, L. K., A one-step synthesis of azide-tagged carbohydrates: versatile intermediates for glycotechnology. Synlett 2006, (3), 455-459.
621 Rozkiewicz, D. I.; Janczewski, D.; Verboom, W.; Ravoo, B. J.; Reinhoudt, D. N., "Click" chemistry by microcontact printing. Angew. Chem., Int. Ed. 2006, 45, (32), 5292-5296.
620 Rohde, R. D.; Agnew, H. D.; Yeo, W.-S.; Bailey, R. C.; Heath, J. R., A Non-Oxidative Approach toward Chemically and Electrochemically Functionalizing Si(111). J. Am. Chem. Soc. 2006, 128, (29), 9518-9525.
619 Reddy, K. R.; Rajgopal, K.; Kantam, M. L., Copper(II)-promoted regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles in water. Synlett 2006, (6), 957-959.
618 Quemener, D.; Davis, T. P.; Barner-Kowollik, C.; Stenzel, M. H., RAFT and click chemistry: A versatile approach to well-defined block copolymers. Chem. Commun. 2006, (48), 5051-5053.
617 Qin, A.; Haussler, M.; Lam, J. W. Y.; Tse, K. K. C.; Tang, B. Z., Synthesis of a hyperbranched polytriazole by 1,3-dipolar polycycloaddition. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 681-682.
616 Pore, V. S.; Aher, N. G.; Kumar, M.; Shukla, P. K., Design and synthesis of fluconazole/bile acid conjugate using click reaction. Tetrahedron 2006, 62, (48), 11178-11186.
615 Polanski, J.; Bak, A.; Gieleciak, R.; Magdziarz, T., Modeling Robust QSAR. J. Chem. Inf. Model. 2006, 46, (6), 2310-2318.
614 Pirali, T.; Tron, G. C.; Zhu, J., One-Pot Synthesis of Macrocycles by a Tandem Three-Component Reaction and Intramolecular [3+2] Cycloaddition. Org. Lett. 2006, 8, (18), 4145-4148.
613 Pieters, R. J., Inhibition and detection of galectins. ChemBioChem 2006, 7, (5), 721-728.
612 Paul, A.; Bittermann, H.; Gmeiner, P., Triazolopeptides: chirospecific synthesis and cis/trans prolyl ratios of structural isomers. Tetrahedron 2006, 62, (38), 8919-8927.
611 Parrish, B.; Cha, J., Peptide end-functionalized block copolymers prepared by reversible addition-fragmentation chain transfer polymerization. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 588.
610 Pagliai, F.; Pirali, T.; Del Grosso, E.; Di Brisco, R.; Tron, G. C.; Sorba, G.; Genazzani, A. A., Rapid Synthesis of Triazole-Modified Resveratrol Analogues via Click Chemistry. J. Med. Chem. 2006, 49, (2), 467-470.
609 Ostaci, V.-R.; Celle, C.; Vignaud, G.; Grohens, Y.; Drockenmuller, E., Versatile approach for grafting polymer brushes to "passivated" silicon substrates using click chemistry. PMSE Prepr. 2006, 95, 22-23.
608 Ossipov, D. A.; Hilborn, J., Poly(vinyl alcohol) hydrogels by click chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (1), 212-213.
607 Ossipov, D. A.; Hilborn, J., Poly(vinyl alcohol)-Based Hydrogels Formed by "Click Chemistry". Macromolecules 2006, 39, (5), 1709-1718.
606 Opsteen, J. A.; Dirks, A. J.; van Berkel, S. S.; Hatzakis, N. S.; Brinkhuis, R. P.; Reijnders, M. E. G.; van Hest, J. C. M., Biohybrid block copolymer architectures by "click" chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 17-18.
605 Olsen, C. A.; Christensen, C.; Nielsen, B.; Mohamed, F. M.; Witt, M.; Clausen, R. P.; Kristensen, J. L.; Franzyk, H.; Jaroszewski, J. W., Aminolysis of Resin-Bound N-Nosylaziridine-2-carboxylic Acids. Org. Lett. 2006, 8, (15), 3371-3374.
604 Oh, K.; Guan, Z., A convergent synthesis of new β-turn mimics by click chemistry. Chem. Commun. 2006, (29), 3069-3071.
603 O'Reilly, R. K.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L., Fluorogenic 1,3-dipolar cycloaddition within the hydrophobic core of a shell cross-linked nanoparticle. Chem.--Eur. J. 2006, 12, (26), 6776-6786.
602 O'Reilly, R. K.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L., Facile syntheses of surface-functionalized micelles and shell cross-linked nanoparticles. J. Polym. Sci., Part A: Polym. Chem. 2006, 44, (17), 5203-5217.
601 Nandivada, H.; Chen, H.-Y.; Bondarenko, L.; Lahann, J., Reactive polymer coatings that "click". Angew. Chem., Int. Ed. 2006, 45, (20), 3360-3363.
600 Muralidharan, V.; Muir, T. W., Protein ligation: an enabling technology for the biophysical analysis of proteins. Nat. Methods 2006, 3, (6), 429-438.
599 Muniz, K.; Almodovar, I.; Streuff, J.; Nieger, M., A convenient and highly productive aminohydroxylation protocol employing an osmium-diamine catalyst. Adv. Synth. Catal. 2006, 348, (14), 1831-1835.
598 Montagnat, O. D.; Lessene, G.; Hughes, A. B., Synthesis of azide-alkyne fragments for click' chemical applications; formation of oligomers from orthogonally protected trialkylsilyl-propargyl azides and propargyl alcohols. Tetrahedron Lett. 2006, 47, (39), 6971-6974.
597 Molteni, G.; Bianchi, C. L.; Marinoni, G.; Santo, N.; Ponti, A., Cu/Cu-oxide nanoparticles as catalyst in the "click" azide-alkyne cycloaddition. New J. Chem. 2006, 30, (8), 1137-1139.
596 Molteni, G., 1,3-Dipolar cycloadditions in aqueous media. Heterocycles 2006, 68, (10), 2177-2202.
595 Molander, G. A.; Ham, J., Synthesis of Functionalized Organotrifluoroborates via the 1,3-Dipolar Cycloaddition of Azides. Org. Lett. 2006, 8, (13), 2767-2770.
594 Mobian, P.; Collin, J.-P.; Sauvage, J.-P., Efficient synthesis of a labile copper(I)-rotaxane complex using click chemistry. Tetrahedron Lett. 2006, 47, (28), 4907-4909.
593 Mindt, T. L.; Struthers, H.; Brans, L.; Anguelov, T.; Schweinsberg, C.; Maes, V.; Tourwe, D.; Schibli, R., "Click to Chelate": Synthesis and Installation of Metal Chelates into Biomolecules in a Single Step. J. Am. Chem. Soc. 2006, 128, (47), 15096-15097.
592 Miljanic, O. S.; Dichtel, W. R.; Mortezaei, S.; Stoddart, J. F., Cyclobis(paraquat-p-phenylene)-Based [2]Catenanes Prepared by Kinetically Controlled Reactions Involving Alkynes. Org. Lett. 2006, 8, (21), 4835-4838.
591 Meyer, A.; Bouillon, C.; Vidal, S.; Vasseur, J.-J.; Morvan, F., A versatile reagent for the synthesis of 5'-phosphorylated, 5'-thiophosphorylated or 5'-phosphoramidate-conjugated oligonucleotides. Tetrahedron Lett. 2006, 47, (50), 8867-8871.
590 Messmore, B. W.; Fukukawa, K.-i.; Pressly, E. D.; Hawker, C. J., Poly(ethylene glycol) containing nanostructures with medical imaging applications. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 415-416.
589 Mercer, A. C.; Burkart, M. D., Chemical expansion of cofactor activity. Nat. Chem. Biol. 2006, 2, (1), 8-10.
588 Mason, A. F.; Lohmeijer, B. G. G.; Li, H.; Pratt, R. C.; Liao, Q.; Frank, C. W.; Kingsbury, K.; Waymouth, R. M.; Hedrick, J. L., Organocatalytic polymerization of ethylene oxide and the controlled synthesis of peo-based hydrogel networks. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 99-100.
587 Martin, N.; Solladie, N.; Nierengarten, J.-F., Advances in molecular and supramolecular fullerene chemistry. Electrochem. Soc. Interface 2006, 15, (2), 29-33.
586 Martin, N., New challenges in fullerene chemistry. Chem. Commun. 2006, (20), 2093-2104.
585 Marik, J.; Sutcliffe, J. L., Click for PET: rapid preparation of [18F]fluoropeptides using Cu(I) catalyzed 1,3-dipolar cycloaddition. Tetrahedron Lett. 2006, 47, (37), 6681-6684.
584 Mantovani, G.; Ladmiral, V.; Cauet, S.; Haddleton, D. M., Novel neoglycopolymer ligands obtained from "clickable" scaffold. PMSE Prepr. 2006, 95, 1030-1031.
583 Malkoch, M.; Vestberg, R.; Gupta, N.; Mespouille, L.; Dubois, P.; Mason, A. F.; Hedrick, J. L.; Liao, Q.; Frank, C. W.; Kingsbury, K.; Hawker, C. J., Synthesis of well-defined hydrogel networks using Click chemistry. Chem. Commun. 2006, (26), 2774-2776.
582 Majireck, M. M.; Weinreb, S. M., A Study of the Scope and Regioselectivity of the Ruthenium-Catalyzed [3 + 2]-Cycloaddition of Azides with Internal Alkynes. J. Org. Chem. 2006, 71, (22), 8680-8683.
581 Macmillan, D.; Blanc, J., A novel neoglycopeptide linkage compatible with native chemical ligation. Org. Biomol. Chem. 2006, 4, (15), 2847-2850.
580 Ma, D.-Y.; Wang, D.-X.; Zheng, Q.-Y.; Wang, M.-X., Nitrile biotransformations for the practical synthesis of highly enantiopure azido carboxylic acids and amides, 'click' to functionalized chiral triazoles and chiral beta-amino acids. Tetrahedron: Asymmetry 2006, 17, (16), 2366-2376.
579 Luxenhofer, R.; Lopez-Garcia, M.; Frank, A.; Kessler, H.; Jordan, R., First poly(2-oxazoline)-peptide conjugate for targeted radionuclide cancer therapy. PMSE Prepr. 2006, 95, 283-284.
578 Luxenhofer, R.; Jordan, R., Click Chemistry with Poly(2-oxazoline)s. Macromolecules 2006, 39, (10), 3509-3516.
577 Lutz, J.-F.; Boerner, H. G.; Weichenhan, K., Combining ATRP and "Click" Chemistry: a Promising Platform toward Functional Biocompatible Polymers and Polymer Bioconjugates. Macromolecules 2006, 39, (19), 6376-6383.
576 Luo, Y.; Knuckley, B.; Bhatia, M.; Pellechia, P. J.; Thompson, P. R., Activity-Based Protein Profiling Reagents for Protein Arginine Deaminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently Labeled Probe. J. Am. Chem. Soc. 2006, 128, (45), 14468-14469.
575 Luo, S.; Xu, H.; Mi, X.; Li, J.; Zheng, X.; Cheng, J.-P., Evolution of Pyrrolidine-Type Asymmetric Organocatalysts by "Click" Chemistry. J. Org. Chem. 2006, 71, (24), 9244-9247.
574 Lu, G.; Lam, S.; Burgess, K., An iterative route to "decorated" ethylene glycol-based linkers. Chem. Commun. 2006, (15), 1652-1654.
573 Lu, G.; Burgess, K., A diversity oriented synthesis of 3'-O-modified nucleoside triphosphates for DNA sequencing by synthesis'. Bioorg. Med. Chem. Lett. 2006, 16, (15), 3902-3905.
572 Looper, R. E.; Pizzirani, D.; Schreiber, S. L., Macrocycloadditions Leading to Conformationally Restricted Small Molecules. Org. Lett. 2006, 8, (10), 2063-2066.
571 Loewik, D. W. P. M.; Ayres, L.; Smeenk, J. M.; Van Hest, J. C. M., Synthesis of bio-inspired hybrid polymers using peptide synthesis and protein engineering. Adv. Polym. Sci. 2006, 202, (Peptide Hybrid Polymers), 19-52.
570 Loethen, S.; Ooya, T.; Choi, H. S.; Yui, N.; Thompson, D. H., Synthesis, Characterization, and pH-Triggered Dethreading of a-Cyclodextrin-Poly(ethylene glycol) Polyrotaxanes Bearing Cleavable Endcaps. Biomacromolecules 2006, 7, (9), 2501-2506.
569 Loeber, S.; Huebner, H.; Gmeiner, P., Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype. Bioorg. Med. Chem. Lett. 2006, 16, (11), 2955-2959.
568 Loaiza, P. R.; Lober, S.; Hubner, H.; Gmeiner, P., Click chemistry on solid phase: parallel synthesis of N-benzyltriazole carboxamides as super-potent G-protein coupled receptor ligands. J. Comb. Chem. 2006, 8, (2), 252-61.
567 Liu, Q.; Chen, Y., Synthesis of well-defined macromonomers by the combination of atom transfer radical polymerization and a click reaction. J. Polym. Sci., Part A: Polym. Chem. 2006, 44, (20), 6103-6113.
566 Link, A. J.; Vink, M. K. S.; Agard, N. J.; Prescher, J. A.; Bertozzi, C. R.; Tirrell, D. A., Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, (27), 10180-10185.
565 Lin, P.-C.; Ueng, S.-H.; Tseng, M.-C.; Ko, J.-L.; Huang, K.-T.; Yu, S.-C.; Adak, A. K.; Chen, Y.-J.; Lin, C.-c., Site-specific protein modification through CuI-catalyzed 1,2,3-triazole formation and its implementation in protein microarray fabrication. Angew. Chem., Int. Ed. 2006, 45, (26), 4286-4290.
564 Liebert, T.; Haensch, C.; Heinze, T., Click chemistry with polysaccharides. Macromol. Rapid Commun. 2006, 27, (3), 208-213.
563 Liang, F.-S.; Brik, A.; Lin, Y.-C.; Elder, J. H.; Wong, C.-H., Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates. Bioorg. Med. Chem. 2006, 14, (4), 1058-1062.
562 Li, Z. a.; Zeng, Q.; Li, Z.; Dong, S.; Zhu, Z.; Li, Q.; Ye, C.; Di, C. a.; Liu, Y.; Qin, J., An Attempt To Modify Nonlinear Optical Effects of Polyurethanes by Adjusting the Structure of the Chromophore Moieties at the Molecular Level Using "Click" Chemistry. Macromolecules 2006, 39, (24), 8544-8546.
561 Li, J.; Zheng, M.; Tang, W.; He, P.-L.; Zhu, W.; Li, T.; Zuo, J.-P.; Liu, H.; Jiang, H., Syntheses of triazole-modified Zanamivir analogues via click chemistry and anti-AIV activities. Bioorg. Med. Chem. Lett. 2006, 16, (19), 5009-13.
560 Li, C.; Finn, M. G., Click chemistry in materials synthesis. II. Acid-swellable crosslinked polymers made by copper-catalyzed azide-alkyne cycloaddition. J. Polym. Sci., Part A: Polym. Chem. 2006, 44, (19), 5513-5518.
559 Lee, J. W.; Kim, J. H.; Kim, B.-K.; Shin, W. S.; Jin, S.-H., Synthesis of FrÚchet type dendritic benzyl propargyl ether and FrÚchet type triazole dendrimer. Tetrahedron 2006, 62, (5), 894-900.
558 Lee, J. W.; Kim, J. H.; Kim, B.-K.; Kim, J. H.; Shin, W. S.; Jin, S.-H., Convergent synthesis of PAMAM dendrimers using click chemistry of azide-functionalized PAMAM dendrons. Tetrahedron 2006, 62, (39), 9193-9200.
557 Lee, J. W.; Kim, J. H.; Kim, B.-K., Synthesis of azide-functionalized PAMAM dendrons at the focal point and their application for synthesis of PAMAM-like dendrimers. Tetrahedron Lett. 2006, 47, (16), 2683-2686.
556 Lee, J. W.; Kim, B.-K.; Kim, J. H.; Shin, W. S.; Jin, S.-H., Facile Approach for Diblock Codendrimers by Fusion between FrÚchet Dendrons and PAMAM Dendrons. J. Org. Chem. 2006, 71, (13), 4988-4991.
555 Lee, J. W.; Kim, B.-K.; Kim, H. J.; Han, S. C.; Shin, W. S.; Jin, S.-H., Convergent Synthesis of Symmetrical and Unsymmetrical PAMAM Dendrimers. Macromolecules 2006, 39, (6), 2418-2422.
554 Lee, J. W.; Kim, B.-K., Synthesis of symmetric and unsymmetric triazole dendrimers via dipolar cycloaddition reaction. Synthesis 2006, (4), 615-618.
553 Lee, C.-C.; Sui, G.; Elizarov, A.; Kolb, H. C.; Huang, J.; Heath, J. R.; Phelps, M. E.; Quake, S. R.; Tseng, H.-R.; Wyatt, P.; Daridon, A. Microfluidic devices with chemical reaction circuits. 2005-US44072 2006071470, 20051205., 2006.
552 Lee, B.-Y.; Park, S. R.; Jeon, H. B.; Kim, K. S., A new solvent system for efficient synthesis of 1,2,3-triazoles. Tetrahedron Lett. 2006, 47, (29), 5105-5109.
551 Lecomte, P.; Riva, R.; Schmeits, S.; Rieger, J.; Van Butsele, K.; Jerome, C.; Jerome, R., New prospects for the grafting of functional groups onto aliphatic polyesters. Ring-opening polymerization of α- or γ-substituted ε-caprolactone followed by chemical derivatization of the substituents. Macromol. Symp. 2006, 240, (Recent Trends in Ionic Polymerization), 157-165.
550 Laurent, B. A.; Grayson, S. M., Synthesis and functionalization of cyclic poly(hydroxystyrene) derivatives. PMSE Prepr. 2006, 95, 411-412.
549 Laurent, B. A.; Grayson, S. M., An Efficient Route to Well-Defined Macrocyclic Polymers via "Click" Cyclization. J. Am. Chem. Soc. 2006, 128, (13), 4238-4239.
548 Larsen, K.; Thygesen, M. B.; Guillaumie, F.; Willats, W. G. T.; Jensen, K. J., Solid-phase chemical tools for glycobiology. Carbohydr. Res. 2006, 341, (10), 1209-1234.
547 Lambermon, M. H. L.; Hendriks, L. J. A.; Schoffelen, S.; Vos, M. R. J.; Hatzakis, N. S.; Carette, N.; Rowan, A. E.; Cornelissen, J. L. M.; Michon, T.; Sommerdijk, N. A. J. M.; von Hest, J. C. M., Assembly strategies for enzyme immobilization. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 209-210.
546 Ladmiral, V.; Mantovani, G.; Clarkson, G. J.; Cauet, S.; Irwin, J. L.; Haddleton, D. M., Synthesis of Neoglycopolymers by a Combination of "Click Chemistry" and Living Radical Polymerization. J. Am. Chem. Soc. 2006, 128, (14), 4823-4830.
545 Kottani, R.; Valiulin, R. A.; Kutateladze, A. G., Direct screening of solution phase combinatorial libraries encoded with externally sensitized photolabile tags. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, (38), 13917-13921.
544 Kondoh, A.; Yorimitsu, H.; Oshima, K., Nucleophilic aromatic substitution reaction of nitroarenes with alkyl- or arylthio groups in dimethyl sulfoxide by means of cesium carbonate. Tetrahedron 2006, 62, (10), 2357-2360.
543 Kolb, H. C.; Walsh, J. C.; Chen, K. Click chemistry method for synthesizing 18F-labeled AZT as molecular imaging probes. 2006-US16088 2006116629, 20060427., 2006.
542 Kolb, H. C.; Mocharla, V. P.; Walsh, J. C. In situ click chemistry method for screening high affinity molecular imaging probes. 2006-US16428 2006116736, 20060427., 2006.
541 Kolakowski, R. V.; Shangguan, N.; Williams, L. J., Thioamides via thiatriazolines. Tetrahedron Lett. 2006, 47, (7), 1163-1166.
540 Kolakowski, R. V.; Shangguan, N.; Sauers, R. R.; Williams, L. J., Mechanism of Thio Acid/Azide Amidation. J. Am. Chem. Soc. 2006, 128, (17), 5695-5702.
539 Kim, T.-D.; Luo, J.; Tian, Y.; Ka, J.-W.; Tucker, N. M.; Haller, M.; Kang, J.-W.; Jen, A. K. Y., Diels-Alder "Click Chemistry" for highly efficient electrooptic polymers. Macromolecules 2006, 39, (5), 1676-1680.
538 Kim, T.-D.; Luo, J.; Chen, B.; Hau, S.; Ka, J.-W.; Tian, Y.; Jang, S.-H.; Tucker, N.; Jen, A. K. Y., A new approach to highly efficient electro-optic polymers using Diels-Alder "click chemistry". Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (1), 190-191.
537 Kim, D.-W.; Lim, S.-G.; Jun, C.-H., Recyclable Self-Assembly-Supported Catalyst for Chelation-Assisted Hydroacylation of an Olefin with a Primary Alcohol. Org. Lett. 2006, 8, (14), 2937-2940.
536 Kellogg, R. M., Multicomponent reactions with ketene imine intermediates formed from the reaction of sulfonyl azides with acetylenes. Chemtracts 2006, 19, (1), 31-37.
535 Kantam, M. L.; Jaya, V. S.; Sreedhar, B.; Rao, M. M.; Choudary, B. M., Preparation of alumina supported copper nanoparticles and their application in the synthesis of 1,2,3-triazoles. J. Mol. Catal. A: Chem. 2006, 256, (1-2), 273-277.
534 Kalia, J.; Raines, R. T., Reactivity of Intein thioesters: appending a functional group to a protein. ChemBioChem 2006, 7, (9), 1375-1383.
533 Kaik, M.; Gawronski, J., Unprecedented Selectivity in the Formation of Large-Ring Oligoimines from Conformationally Bistable Chiral Diamines. Org. Lett. 2006, 8, (14), 2921-2924.
532 Kade, M.; Vestberg, R.; Malkoch, M.; Wu, P.; Fokin, V. V.; Finn, M. G.; Sharpless, K. B.; Hawker, C., A covalently bonded layer-by-layer assembly of dendrimers by 'click' chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 376-377.
531 Kacprzak, K. M.; Maier, N. M.; Lindner, W., Highly efficient immobilization of Cinchona alkaloid derivatives to silica gel via click chemistry. Tetrahedron Lett. 2006, 47, (49), 8721-8726.
530 Ju, Y.; Kumar, D.; Varma, R. S., Revisiting nucleophilic substitution reactions: microwave-assisted synthesis of azides, thiocyanates, and sulfones in an aqueous medium. J. Org. Chem. 2006, 71, (17), 6697-6700.
529 Johnson, J. A.; Lewis, D. R.; Diaz, D. D.; Finn, M. G.; Koberstein, J. T.; Turro, N. J., Synthesis of Degradable Model Networks via ATRP and Click Chemistry. J. Am. Chem. Soc. 2006, 128, (20), 6564-6565.
528 Jen, A. K. Y., Controlled self-assembly and "click" processing of organic electro-optic materials for exceptional photonic properties and applications. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 988-989.
527 Ijsselstijn, M.; Cintrat, J.-C., Click chemistry with ynamides. Tetrahedron 2006, 62, (16), 3837-3842.
526 Hotha, S.; Kashyap, S., "Click chemistry" inspired synthesis of pseudo-oligosaccharides and amino acid glycoconjugates. [Erratum to document cited in CA144:129164]. J. Org. Chem. 2006, 71, (2), 852.
525 Hotha, S.; Kashyap, S., "Click Chemistry" inspired synthesis of pseudo-oligosaccharides and amino acid glycoconjugates. J. Org. Chem. 2006, 71, (1), 364-367.
524 Hooker, J. M.; Esser-Kahn, A. P.; Francis, M. B., Modification of Aniline Containing Proteins Using an Oxidative Coupling Strategy. J. Am. Chem. Soc. 2006, 128, (49), 15558-15559.
523 Hoogenboom, R.; Moore, B. C.; Schubert, U. S., Synthesis of star-shaped poly(.vepsiln.-caprolactone) via click' chemistry and supramolecular click' chemistry. Chem. Commun. 2006, (38), 4010-4012.
522 Holub, J. M.; Jang, H.; Kirshenbaum, K., Clickity-click: highly functionalized peptoid oligomers generated by sequential conjugation reactions on solid-phase support. Org. Biomol. Chem. 2006, 4, (8), 1497-1502.
521 Hiroya, K.; Matsumoto, S.; Ashikawa, M.; Ogiwara, K.; Sakamoto, T., Cyclization reactions of homopropargyl azide derivatives catalyzed by PtCl4 in ethanol solution: synthesis of functionalized pyrrole derivatives. Org. Lett. 2006, 8, (23), 5349-5352.
520 Hatzakis, N. S.; Engelkamp, H.; Velonia, K.; Hofkens, J.; Christianen, P. C. M.; Svendsen, A.; Patkar, S. A.; Vind, J.; Maan, J. C.; Rowan, A. E.; Nolte, R. J. M., Synthesis and single enzyme activity of a clicked lipase-BSA hetero-dimer. Chem. Commun. 2006, (19), 2012-2014.
519 Hassane, F. S.; Frisch, B.; Schuber, F., Targeted Liposomes: Convenient Coupling of Ligands to Preformed Vesicles Using "Click Chemistry". Bioconjugate Chem. 2006, 17, (3), 849-854.
518 Hasegawa, T.; Umeda, M.; Numata, M.; Li, C.; Bae, A.-H.; Fujisawa, T.; Haraguchi, S.; Sakurai, K.; Shinkai, S., 'Click chemistry' on polysaccharides: a convenient, general, and monitorable approach to develop (1-->3)-β-D-glucans with various functional appendages. Carbohydr. Res. 2006, 341, (1), 35-40.
517 Hasegawa, T.; Umeda, M.; Numata, M.; Fujisawa, T.; Haraguchi, S.; Sakurai, K.; Shinkai, S., Click chemistry on curdlan: A regioselective and quantitative approach to develop artificial β-1,3-Glucans with various functional appendages. Chem. Lett. 2006, 35, (1), 82-83.
516 Hamdi, N.; Fischmeister, C.; Dixneuf, P. H.; Nievas, A. R., Regioselective synthesis of a new [1,2,3]-triazoles directly from imidates. J. Heterocycl. Chem. 2006, 43, (2), 499-501.
515 Hagenstein, M. C.; Sewald, N., Chemical tools for activity-based proteomics. J. Biotechnol. 2006, 124, (1), 56-73.
514 Hafren, J.; Zou, W.; Cordova, A., Heterogeneous 'organoclick' derivatization of polysaccharides. Macromol. Rapid Commun. 2006, 27, (16), 1362-1366.
513 Haddleton, D. M.; Mantovani, G.; Ladmiral, V., Peptide glycopolymer conjugates via living radical polymerization and click chemistry. PMSE Prepr. 2006, 94, 186.
512 Gupta, N.; Vestberg, R.; Malkoch, M.; Hikita, S. T.; Thibault, R. J.; Lingwood, M.; McCarney, E.; Han, S.-i.; Clegg, D. O.; Hawker, C. J., Characterization of poly(ethylene glycol) hydrogels formed via click chemistry. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 25-26.
511 Guo, Z.; Lei, A.; Liang, X.; Xu, Q., Click chemistry: a new facile and efficient strategy for preparation of functionalized HPLC packings. Chem. Commun. 2006, (43), 4512-4514.
510 Gruijters, B. W. T.; Broeren, M. A. C.; Van Delft, F. L.; Sijbesma, R. P.; Hermkens, P. H. H.; Rutjes, F. P. J. T., Catalyst Recycling via Hydrogen-Bonding-Based Affinity Tags. Org. Lett. 2006, 8, (15), 3163-3166.
509 Groothuys, S.; Kuijpers, B. H. M.; Quaedflieg, P. J. L. M.; Roelen, H. C. P. F.; Wiertz, R. W.; Blaauw, R. H.; van Delft, F. L.; Rutjes, F. P. J. T., Chemoenzymatic synthesis of triazole-linked glycopeptides. Synthesis 2006, (18), 3146-3152.
508 Grimme, S.; Mueck-Lichtenfeld, C.; Wuerthwein, E.-U.; Ehlers, A. W.; Goumans, T. P. M.; Lammertsma, K., Consistent Theoretical Description of 1,3-Dipolar Cycloaddition Reactions. J. Phys. Chem. A 2006, 110, (8), 2583-2586.
507 Grayson, S. M.; Laurent, B. A.; Eugene, D. M., Use of "Click" chemistry to prepare functional cyclic polymers for transdermal drug delivery. PMSE Prepr. 2006, 95, 827-828.
506 Graham, D.; Faulds, K.; Smith, W. E., Biosensing using silver nanoparticles and surface enhanced resonance Raman scattering. Chem. Commun. 2006, (42), 4363-4371.
505 Graham, D.; Enright, A., Cycloadditions as a method for oligonucleotide conjugation. Curr. Org. Synth. 2006, 3, (1), 9-17.
504 Gopin, A.; Ebner, S.; Attali, B.; Shabat, D., Enzymatic Activation of Second-Generation Dendritic Prodrugs: Conjugation of Self-Immolative Dendrimers with Poly(ethylene glycol) via Click Chemistry. Bioconjugate Chem. 2006, 17, (6), 1432-1440.
503 Gopi, H. N.; Tirupula, K. C.; Baxter, S.; Ajith, S.; Chaiken, I. M., Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120. ChemMedChem 2006, 1, (1), 54-57.
502 Goodall, G. W.; Hayes, W., Advances in cycloaddition polymerizations. Chem. Soc. Rev. 2006, 35, (3), 280-312.
501 Golas, P. L.; Tsarevsky, N. V.; Sumerlin, B. S.; Matyjaszewski, K., Tuning the efficiency of click reactions using polymers prepared by atom transfer radical polymerization. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2006, 47, (2), 737-738.
500 Golas, P. L.; Tsarevsky, N. V.; Sumerlin, B. S.; Matyjaszewski, K., Catalyst Performance in "Click" Coupling Reactions of Polymers Prepared by ATRP: Ligand and Metal Effects. Macromolecules 2006, 39, (19), 6451-6457.
499 Goess, B. C.; Hannoush, R. N.; Chan, L. K.; Kirchhausen, T.; Shair, M. D., Synthesis of a 10,000-Membered Library of Molecules Resembling Carpanone and Discovery of Vesicular Traffic Inhibitors. J. Am. Chem. Soc. 2006, 128, (16), 5391-5403.
498 Girard, C.; Oenen, E.; Aufort, M.; Beauviere, S.; Samson, E.; Herscovici, J., Reusable Polymer-Supported Catalyst for the [3+2] Huisgen Cycloaddition in Automation Protocols. Org. Lett. 2006, 8, (8), 1689-1692.
497 Gierlich, J.; Burley, G. A.; Gramlich, P. M. E.; Hammond, D. M.; Carell, T., Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA. Org. Lett. 2006, 8, (17), 3639-3642.
496 Gheorghe, A.; Matsuno, A.; Reiser, O., Expedient immobilization of TEMPO by copper-catalyzed azide-alkyne [3+2]-cycloaddition onto polystyrene resin. Adv. Synth. Catal. 2006, 348, (9), 1016-1020.
495 Gheorghe, A.; Cuevas-Yanez, E.; Horn, J.; Bannwarth, W.; Narsaiah, B.; Reiser, O., A facile strategy to a new fluorous-tagged, immobilized TEMPO catalyst using a click reaction, and its catalytic activity. Synlett 2006, (17), 2767-2770.
494 Gerard, B.; Ryan, J.; Beeler, A. B.; Porco, J. A., Jr., Synthesis of 1,4,5-trisubstituted-1,2,3-triazoles by copper-catalyzed cycloaddition-coupling of azides and terminal alkynes. Tetrahedron 2006, 62, (26), 6405-6411.
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492 Gao, H.; Matyjaszewski, K., Synthesis of Star Polymers by a Combination of ATRP and the "Click" Coupling Method. Macromolecules 2006, 39, (15), 4960-4965.
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290 Knoepfel, T. F.; Zarotti, P.; Ichikawa, T.; Carreira, E. M., Catalytic, Enantioselective, Conjugate Alkyne Addition. J. Am. Chem. Soc. 2005, 127, (27), 9682-9683.
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288 Klok, H.-A., Biological-synthetic hybrid block copolymers: Combining the best from two worlds. J. Polym. Sci., Part A: Polym. Chem. 2005, 43, (1), 1-17.
287 Kim, T.-D.; Kang, J.-W.; Luo, J.; Haller, M.; Tian, Y.; Chen, B.; Hau, S.; Shi, Z.; Jen, A. K. Y., Exceptional photonic properties through click chemistry and self-assembly of fluoro-dendrimers and polymers. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2005, 46, (2), 601-602.
286 Kaval, N.; Ermolat'ev, D.; Appukkuttan, P.; Dehaen, W.; Kappe, C. O.; Van der Eycken, E., The Application of "Click Chemistry" for the Decoration of 2(1H)-Pyrazinone Scaffold: Generation of Templates. J. Comb. Chem. 2005, 7, (3), 490-502.
285 Kaplan, G.; Drake, G.; Tollison, K.; Hall, L.; Hawkins, T., Synthesis, characterization, and structural investigations of 1-amino-3-substituted-1,2,3-triazolium salts, and a new route to 1-substituted-1,2,3-triazoles. J. Heterocycl. Chem. 2005, 42, (1), 19-29.
284 Kaleta, Z.; Egyed, O.; Soos, T., Fluorous click chemistry as a practical tagging method. Org. Biomol. Chem. 2005, 3, (12), 2228-2230.
283 Kaiser, J.; Kinderman, S. S.; van Esseveldt, B. C. J.; van Delft, F. L.; Schoemaker, H. E.; Blaauw, R. H.; Rutjes, F. P. J. T., Synthetic applications of aliphatic unsaturated a-H-a-amino acids. Org. Biomol. Chem. 2005, 3, (19), 3435-3467.
282 Kacprzak, K.; Migas, M.; Plutecka, A.; Rychlewska, U.; Gawronski, J., The library of Cinchona alkaloidal 1,2,3-triazole derivatives: Structure and facile access by "click chemistry". Heterocycles 2005, 65, (8), 1931-1938.
281 Kacprzak, K., Efficient one-pot synthesis of 1,2,3-triazoles from benzyl and alkyl halides. Synlett 2005, (6), 943-946.
280 Kacprzak, K., Click chemistry - a revolution in organic synthesis? Wiadomosci Chemiczne 2005, 59, (7-8), 583-611.
279 Jordan, B. J.; Carroll, J. B.; Xu, H.; Erdogan, B.; Lee, L.; Cheng, L.; Tiernan, C.; Cooke, G.; Rotello, V. M., Site isolated redox behavior in flavin functionalized random polystyrene copolymers. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2005, 46, (2), 1157-1158.
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274 Jen, A.; Luo, J.; Kim, T.-D.; Chen, B.; Jang, S.-H.; Kang, J.-W.; Tucker, N. M.; Hau, S.; Tian, Y.; Ka, J.-W.; Haller, M.; Liao, Y.; Robinson, B.; Dalton, L.; Herman, W., Exceptional electro-optic properties through molecular design and controlled self-assembly. Proc. SPIE-Int. Soc. Opt. Eng. 2005, 5935, (Linear and Nonlinear Optics of Organic Materials V), 593506/1-593506/13.
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