2005 Winter Research Symposium

See who won below.

When

Thursday, February 3, 2005.

Where

The Committee Lecture Hall (Skaggs Institute, MBB) and the Timken Amphitheater (Green Hospital) at TSRI

Who

Graduate students, Research Associates, Scientific Associates, and Staff Scientists at TSRI will give oral presentations at the 2005 Winter Symposium.

What

Presenters' presentation will be judged and the top speakers in each category will win a $700 travel award. Second place winners in each category will receive a $300 travel award. All participants receive a $25 gift card to the UCSD Bookstore just for presenting.

Symposia Categories

The 2005 Winter Symposium is divided into four sections. Each section will be headed by a Keynote Speaker followed by 5 or 6 abstract presentations.

• Neurosciences (includes neuropharmacology and neurobiology)
• Cell and Molecular Biology (includes cell biology, molecular biology and molecular & experimental medicine)
• Chemistry and Structural Biology (includes synthetic chemistry, biological chemistry, chemical biology, and structural biology)
• Immunology (includes immunology and immunobiology)

Scheduled Keynote Speakers

• Immunology: Melvin Cohn, Salk Institute for Biological Sciences. "Theoretical studies of immune behaviour: old ideas whose time has come"

• Neurosciences: Howard L. Fields, UCSF. "Dopamine in the nucleus accumbens: incentive or reward?"

• Cell & Molecular Biology: Brain Kobilka, Stanford University. "Regulation of cardiomyocyte function by beta1 and beta2 adrenoceptors: evidence for subtype-specific signaling compartments"

• Chemistry & Structural Biology: Partho Ghosh, UCSD. "Injection of bacterial cytotoxins into mammalian cells by the type III system"

If you would like to meet with a Keynote Speaker, please contact the appropriate Session Organizer.

Session Organizers

• Sandy Ghozland: Neurosciences
• Jasim Ahamed: Cell and Molecular Biology
• John Luz: Chemistry and Structural Biology
• Ralph Pantophlet: Immunology

For general questions regarding the 2005 Winter Symposium, please contact Ralph Pantophlet. For questions about a given section please contact the organizer of that section indicated above.

Schedule of Speakers

Morning Session 1:
Valerie Timken Amphitheater
Cell & Molecular Biology

• 9:00-9:45am => Keynote Speaker: Brian Kobilka (Stanford University); Regulation of cardiomyocyte function by beta1 and beta2 adrenoceptors: evidence for subtype-specific signaling compartments
• 9:45-10:00am => Gourab Bhattacharjee (Edgington lab); The effect of Grp78 inhibition on coagulation
• 10:00-10:15am => Defne Yarar (Schmid lab); A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytocis
• 10:15-10:30am => Coffee and Refreshments break
• 10:30-10:45am => Jianming Xie (Schultz lab); An expanded genetic code -a tool for exploring protein structure and function
• 10:45-11:00am => Olivier Pertz (Klemke lab); Spatio-temporal analysis of RhoA activity reveals its signaling complexity in cell migration
• 11:00-11:15am => Xiaoqin Ye (Chun lab); LPA3-mediated lysophosphatidic acid signalling in implantation and embryo spacing

Morning Session 2:
Committee Lecture Hall
Immunology

• 9:00-9:45am => Keynote Speaker: Melvin Cohn (Salk Institute); Theoretical studies of immune behaviour: old ideas whose time has come
• 9:45-10:00am => Cindy Takeuchi (Wentworth lab); Cholesterol ozonolysis products enhance atherogenic marcophage activity
• 10:00-10:15am => Diana Bowley (Burton lab); Comparative analysis of antibodies derived from yeast and phage display using an immune library from a long-term HIV-1-infected donor with broadly neutralizing serum
• 10:15-10:30am => Coffee and Refreshments break
• 10:30-10:45am => Dirk Zajonc (Wilson lab); Structural studies of lipid antigen presentation by CD1
• 10:45-11:00am => Fei Liu (Whitton lab); A new look at CD8+ T cell responses to virus infection in vivo
• 11:00-11:15am => Rachel Tilley (Mackman lab); Genetic reduction of tissue factor does not affect the progression of atherosclerosis in mice
• 11:15-11:30am => Michael Tencati (Mackman lab); AGI-1095: attenuating endotoxemia through a novel mechanism

Lunch (Speakers & organizers only)
Kresge Library, Rm SR401B
11:00am-2:00pm

Afternoon Session 1:
Valerie Timken Amphitheater
Chemistry & Structural Biology

• 2:00-2:45pm => Keynote Speaker: Partho Ghosh (UCSD); Injection of bacterial cytotoxins into mammalian cells by the type III system
• 2:45-3:00pm => Anu Sawkar (Kelly lab); Chemical chaperones increase the cellular activity of glucocerebrosidase: a therapeutic strategy for Gaucher disease
• 3:00-3:15pm => Hao Xu (Nicolaou lab); Biomimetic cascade reactions in organic synthesis: total syntheses of 1-O-methyllateriflorone and gambogin
• 3:15-3:30pm => Coffee and Refreshments break
• 3:30-3:45pm => Holly Heaslet (Stout lab); Structural studies of E. coli transhydrogenase: a multi-technique approach for membrane proteins
• 3:45-4:00pm => Joerg Zimmermann (Romesberg lab); The evolution of protein dynamics
• 4:00-4:15pm => Kelly Lee (Johnson lab); Cooperativity in the dynamic conformational reorganization of a 420 subunit icosahedral capsid
• 4:15-4:30pm => Li Fan (Tainer lab); Archaeal XPB crystal structure reveals a damage verification domain flexibly linked to the helicase core

Afternoon Session 2:
Commitee Lecture Hall
Neurosciences

• 2:00-2:45pm => Keynote Speaker: Howard Fields (UCSF); Dopamine in the nucleus accumbens: incentive or reward?
• 2:45-3:00pm => Thomas Greenwell (Koob lab); Microinfusion of a corticotropin-releasing factor receptor antagonist into the bed nucleus of the stria terminalis attenuates defensive burying behavior
• 3:00-3:15pm => Jilla Sabeti (Gruol lab); Maladaptive changes in hippocampal synaptic transmission and plasticity in response to ethanol exposure in adolescent rats
• 3:15-3:30pm => Coffee and Refreshments break
• 3:30-3:45pm => Andrew Ray (Henriksen lab); Non-dopaminergic ventral tegmental area (Vta) neurons project to cholinergic basal forebrain (Bf) areas
• 3:45-4:00pm => Stevens Rehen (Chun lab); Constitutional aneuploidy in the normal human brain
• 4:00-4:15pm => Matthew Trifilo (Oldstone lab); Extra neural disease manifestations of prion infection

Winners

First place ($700):

• 11:00-11:15am => Xiaoqin Ye (Chun lab); LPA3-mediated lysophosphatidic acid signalling in implantation and embryo spacing
• 10:30-10:45am => Dirk Zajonc (Wilson lab); Structural studies of lipid antigen presentation by CD1
• 2:45-3:00pm => Anu Sawkar (Kelly lab); Chemical chaperones increase the cellular activity of glucocerebrosidase: a therapeutic strategy for Gaucher disease
• 4:00-4:15pm => Matthew Trifilo (Oldstone lab); Extra neural disease manifestations of prion infection

Second place ($300):

• 10:00-10:15am => Defne Yarar (Schmid lab); A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytocis
• 10:45-11:00am => Fei Liu (Whitton lab); A new look at CD8+ T cell responses to virus infection in vivo
• 4:00-4:15pm => Kelly Lee (Johnson lab); Cooperativity in the dynamic conformational reorganization of a 420 subunit icosahedral capsid
• 3:45-4:00pm => Stevens Rehen (Chun lab); Constitutional aneuploidy in the normal human brain

For questions and more information, contact us via e-mail.