Publications of Min Guo, Ph.D.
1. Tu X, Wang J, Guo M, Zheng D, Teng M, Niu L, Liu Q, Huang Q, Hao Q. Purification, partial characterization, crystallization and preliminary X-ray diffraction of two cysteine-rich secretory proteins from Naja atra and Trimeresurus stejnegeri venoms, Acta Cryst. D, 2004; 60: 1108-1111
2. Guo M, Teng M, Niu L, Liu Q, Huang Q, Hao Q. Crystal structure of cysteine-rich secretory protein stecrisp reveals the cysteine-rich domain has a K+-channel inhibitor-like fold. J. Biol. Chem., 2005 Apr; 280: 12405-12412
3. Wang D, Guo M, Liang Z, Fan J, Zhu Z, Zang J, Zhu Z, Li X, Teng M, Niu L, Dong Y, and Liu P. Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites. J. Biol. Chem., 2005 Jun; 280: 22962 – 22967
4. Wang J, Shen B, Guo M, Lou X, Duan Y, Cheng XP, Teng M, Niu L, Liu Q, Huang Q, Hao Q. Blocking effect and crystal structure of natrin toxin, a cysteine-rich secretory protein from Naja atra venom that targets the BKCa channel. Biochemistry, 2005 Aug 2;44 (30):10145-52
5. Fan J, Wang D, Liang Z, Guo M, Teng M, Niu L. Maize uroporphyrinogen III methyltransferase: overexpression of the functional gene fragments in Escherichia coli and one-step purification. Protein Expr Purif., 2006 Mar;46(1):40-6
6. Li X, Guo M, Fan J, Tang W, Wang D, Ge H, Rong H, Teng M, Niu L, Liu Q, Hao Q. Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Sacchromyces cerevisiae: a special subgroup of the type III extradiol dioxygenases. Protein Sci., 2006 Apr;15(4):761-73
7. Guo M, Xu F, Yamada J, Egelhofer T, Gao Y, Hartzog GA, Teng M, Niu L. Core structure of the yeast Spt4-Spt5 Complex: a conserved module for regulation of transcription elongation. Structure, 2008 Nov 12;16:1649-1658
8. Fang P, Wang J, Li X, Guo M, Xing L, Cao X, Zhu Y, Gao Y, Niu L, Teng M. Crystallization and preliminary X-ray analysis of Escherichia coli Rnase G. Acta Cryst. F, 2009 Jun 1; 65:586-8
9. Yang XL, Guo M, Kapoor M, Ewalt KL, Otero FJ, Skene RJ, McRee DE, Schimmel P. Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase. Structure, 2007 Jul;15(7):793-805
10. Beebe K, Waas W, Druzina Z, Guo M, Schimmel P. A universal plate format for increased throughput of assays that monitor multiple aminoacyl transfer RNA synthetase activities. Anal Biochem., 2007 Sep 1;368(1):111-21
11. Guo M, Ignatov M, Musier-Forsyth K, Schimmel P, Yang XL. Crystal structure of tetrameric form of human lysyl-tRNA synthetase: implications for multisynthetase complex formation. Proc. Natl. Acad. Sci. USA, 2008 Feb 19;105(7):2331-6
12. Schimmel P, Guo M. Ancient tRNA synthetase meets modern structural biology. Structure, 2009 Mar 11;17: 315-7
13. Schimmel P, Guo M. A tipping point for mistranslation and disease. Nature Structure Molecular Biology, 2009 Apr 1;16(4): 348-9
14. Guo M, Chong YE, Beebe K, Shapiro R, Yang XL, Schimmel P. The C-Ala domain brings together editing and aminoacylation functions on one tRNA. Science, 2009 Aug 7; 325;744-7
15. Guo RT, Chong YE, Guo M, Yang XL. Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis. J. Biol. Chem., 2009 Oct 16; 284(42):28968-76
16. Guo M, Chong YE, Shapiro R, Beebe K, Yang XL, Schimmel P. Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 2009 Dec 10; 462:808-12
17. Zhou Q, Kapoor M, Guo M, Belani R, Xu X, Kiosses WB, Hanan M, Park C, Armour E, Do MH, Nangle LA, Schimmel P, Yang XL. Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality. Nat. Struct. Mol. Biol., 2010 Jan 17; 17:57-61
18. Guo M, Schimmel P, Yang XL. Functional expansion of human tRNA synthetases achieved by structural inventions. FEBS Lett., 2010 Jan 21; 584:434-42
19. Guo M, Shapiro R, Schimmel P, Yang XL. Introduction of a leucine half-zipper engenders multiple high quality crystals of a recalcitrant tRNA synthetase. Acta Cryst. D, 2010 Mar; 66:243-50
20. Guo M, Yang XL, Schimmel P. New functions of tRNA synthetases beyond translation. Nature Reviews Molecular Cell Biology, 2010 Sep;11(9):668-74
21. Guo M, Shapiro R, Morris GM, Yang XL, Schimmel P. Packaging HIV virion components through dynamic equilibria of a human tRNA synthetase. Journal of Physical Chemistry, 2010 Dec;114(49):16273-9
22. Fang P, Zhang HM, Shapiro R, Marshall AG, Schimmel P, Yang XL, Guo M. Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex. Proc. Natl. Acad. Sci. USA, 2011 May 17;108(20):8239-44
23. Kumar A, Fang P, Park H, Guo M, Nettles KW, Disney MD. A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome. Chembiochem, 2011 Sep;12(14):2140-2
24. He W, Zhang HM, Chong YE, Guo M, Marshall AG, Yang XL. Dispersed disease-causing neomorphic mutations on a single protein promote the same localized conformational opening. Proc. Natl. Acad. Sci. USA, 2011 Jul 26;108(30):12307-12
25. Kumar A, Park H, Fang P, Parkesh R, Guo M, Nettles KW, Disney MD. Myotonic Dystrophy Type 1 RNA Crystal Structures Reveal Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations. Biochemistry, 2011 Nov 15;50(45):9928-35.
26. Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem Biol., 2012 Jan 20;7(1):160-5.
27. Guo M, Schimmel P. Structural analyses clarify the complex control of mistranslation by tRNA synthetases. Curr. Opin. Struct. Biology, 2012 Feb; 22(1):119-26.
28. Xu XL, Shi Y, Zhang HM, Marshall AG, Guo M, Kishi S, Yang XL. Unique domain appended to vertebrate tRNA synthetase is essential for vascular development. Nature Communications, 2012 Feb 21; 3:681
29. Sajish M, Zhou Q, Kishi S, Valdez DJ, Kapoor M, Guo M, Kim S, Yang XL. Nuclear Trp-tRNA Synthetase Implicated in Linking IFN-γ Signaling to p53 Activation. Nature Chemical Biology, 2012 [In press]
30. Park MC, Kang T, Jin D, Han JM, Kim SB, Park YC, Cho K, Park YW, Guo M, He W, Yang XL, Paul Schimmel P, Kim S. Secreted Human Gly-tRNA Synthetase Implicated in Defense Against ERK-Activated Tumorigenesis. Proc. Natl. Acad. Sci. USA, 2012 Feb 15. [Epub ahead of print]
31. Guo M, Schimmel P. Homeostatic mechanism by alternative forms of tRNA synthetases. Trends in Biochemistry Sciences, 2012 Oct;37(10):401-3.
32. Wang J, Fang P, Schimmel P, Guo M. Side Chain Independent Recognition of Aminoacyl-Adenylates by the Hint1 Transcription Suppressor. Journal of Physical Chemistry, 2012 Jun 14;116(23):6798-805
33. Ofir-Birin Y, Fang P, Bennett SP, Zhang HM, Wang J, Rachmin I, Shapiro R, Song J, Dagan A, Kim S, Marshall AG, Schimmel P, Yang XL, Nechushtan H, Razin E, Guo M. Structural switch of lysyl-tRNA synthetase function between translation and transcription. Mol. Cell, 2012 [In press]
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