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The Sauer Lab

Lymphocyte Signaling in Health and Disease

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Laboratory Address

The Scripps Research Institute
Mailstop IMM-24, Room R219
10550 North Torrey Pines Road
La Jolla, CA 92037, USA.

Lab phone : +1-858-784-7399
Fax: +1-858-784-7422
Email: ksauer@scripps.edu

 

News

Study Points to Potential New Therapies for Cancer and Other Diseases.
web version

Dr. Sauer wins Leukemia and Lymphoma Society Scholar Award
web version/pdf.

 

Publication Highlights

Sauer, K.*, Park, E., Siegemund, S., French, A.R., Wahle, J.A., Sternberg, L., Rigaud, S., Jonsson, A.H., Yokoyama, W.M. and Huang, Y.H.* (2013) Inositol Tetrakisphosphate Limits NK Cell Effector Functions by Controlling PI3K Signaling. Blood 121, 286-297. *Co-corresponding authors. abstract

Sauer, K.*, and Cooke, M.P. Regulation of Immune Cell Development Through Soluble Inositol-1,3,4,5-tetrakisphosphate. (2010) Nature Reviews Immunology 10, 257-271. *Corresponding author. abstract

Barouch-Bentov, R., Che, J., Lee, C.C., Yang, Y., Herman, A., Jia, Y., Velentza, A., Watson, J., Sternberg, L., Kim, S., Ziaee, N., Miller, A., Jackson, C., Fujimoto, M., Young, M., Batalov, S., Liu, Y., Warmuth, M., Wiltshire, T., Cooke, M.P., and Sauer, K. (2009) A Conserved Salt Bridge in the G Loop of Multiple Protein Kinases Is Important for Catalysis and for in Vivo Lyn Function. Molecular Cell 33, 43-52. abstract

Huang, Y. H., Grasis, J., Miller, A. T., Xu, R., Soonthornvacharin, S., Andreotti, A. H., Tsoukas, C. D., Cooke, M. P., and Sauer, K. (2007) Positive Regulation of Itk PH Domain Function by Soluble IP4. Science 316, 886-889. abstract (Free reprint under Publications)