312. P. Nuhant and W. R. Roush, "Enantio- and Diastereoselective Synthesis of N-Acetyl Dihydrotetrafibricin Methyl Ester," J. Am. Chem. Soc. 2013, 135, in press. 10.1021/ja401918r
311. M. Chen and W. R. Roush, "Enantioselective Synthesis of (E)-δ-Silyl-anti Homoallylic Alcohols Via An Enantiodivergent Hydroboration-Crotylboration Reaction of a Racemic Allenylsilane", Org. Lett., 2013, 15 in press. 10.1021/ol4004405
310. H. Yang, C. Pinello, J. Luo, D. Li, Y. Wang, L. Zhao, S. Jahn, A. Saldanha, B. Law, W. Roush, P. Hodder, and D. Liao, "Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents", Mol. Cancer Therap. 2013, in press.
309. A. S. Tsai, M. Chen and W. R. Roush, "Chiral Bronsted Acid Catalyzed Enantioselective Synthesis of anti-Homopropargyl Alcohols via Kinetic Resolution-Aldehyde Allenylboration Using Racemic Allenylboronates," Org. Lett. 2013, 15, in press. 10.1021/ol4003459
308. J. R. Abbott and W. R. Roush, "Stereoselective Synthesis of the Disaccharide Unit of Incednine," Org. Lett. 2013, 15, 62. 10.1021/ol303093z
307. J. G. Geist, R. Barth and W. R. Roush, "Enantioselective Synthesis of the C(1) - C(11) Fragment of Tedanolide C", Org. Lett. 2013, 15, 58. 10.1021/ol303089w
306. M. Chen and W. R. Roush, “Crotylboron-Based Synthesis of the Polypropionate Units of Chaxamycins A/D, Salinisporamycin, and Rifamycin S,” J. Org. Chem. 2012, 77, in press. 10.1021/jo3008226
305. J.-L. Han, M. Chen and W. R. Roush, “Diastereo- and Enantioselective Synthesis of (E)-2-Methyl-1,2-anti-3- pentanediols via Allenylboronate Kinetic Resolution with (dIpc)2BH and Aldehyde Allylboration,” Org. Lett. 2012, 14, 3028. 10.1021/ol3010968
304. M. Chen and W. R. Roush, “Enantioselective Synthesis of anti- and syn-Homopropargyl Alcohols via Chiral Brønsted Acid Catalyzed Asymmetric Allenyboration Reactions,” J. Am. Chem. Soc. 2012, 134, 1094710947. 10.1021/ja3031467
303. A. T. Dossey, J. Whitaker, M. C. A. Dancel, R. Vander Meer, U. R. Bernier, M. Gottardo, and W. R. Roush, “Defensive Spiroketals from Asceles glaber (Phasmatodea): Absolute Configuration and Effects on Ants and Mosquitoes,” J. Chem. Ecol. 2012, 38, 1105.
10.1007/s10886-012-0183-x
302. M. Chen and W. R. Roush, “Enantioselective Synthesis of (+)-Crocacin C. An Example of A Highly Challenging Mismatched Double Asymmetric d-Stannylcrotylboration Reaction,” Org. Lett., 2012, 14, 1880.10.1021/ol300476f
301. M. Chen and W. R. Roush, “Enantioselective Synthesis of (-)-Basiliskamide A,” Org. Lett., 2012, 14, in press (ASAP). 10.1021/ol300282e
300. M. Chen and W. R. Roush, “Highly Stereoselective Synthesis of Anti, Anti-Steriotriads: A Solution to the Challenging Mismatched Double Asymmetric Crotylboration Reactions,” J. Am. Chem. Soc., 2012, 134, 3925. 10.1021/ja300472a
299. J. Y. Choi, M. S. Plummer, J. Starr, C. R. Desbonnet, H. Soutter, J. Chang, J. R. Miller, K. Dillman, A. A. Miller, and W. R. Roush, "Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead Generation,” J. Med. Chem. 2012, 55, 852-870. 10.1021/jm201349f
298. M. Chen and W. R. Roush, “Total Synthesis of (-)-Tirandamycin C,” Org. Lett. 2012, 14, 426. 10.1021/ol203161u
297. M. Ying and W. R. Roush, “"Studies on the Synthesis of Reidispongiolide A: Stereoselective Synthesis of the C(22)-C(36) Fragment,” Tetrahedron 2011, 67, 10274 (invited paper for Symposium-in-Print in honor of Prof. G. Stork’s 90th birthday). 10.1016/j.tet.2011.10.029
296. J. Roth, D. Minond, E. Darout, Q. Liu, J. Lauer, P. Hodder, G. B. Fields, and W. R. Roush, “Identification of Novel, Exosite-Binding Matrix Metalloproteinase-13 Inhibitor Scaffolds,” Bioorg. Med. Chem. Lett. 2011, 21, 7180-7184. 10.1016/j.bmcl.2011.09.077
295. Y. Zhou, J. Agudelo, K. Lu, D. H. Goetz, E. Hansell, Y. T. Chen, W. R. Roush, J. McKerrow, C. S. Craik, S. M. Amberg, and G. Simmons, “Inhibitors of SARS-CoV Entry - Identification using an Internally-Controlled Dual Envelope Pseudovirion Assay,” Antiviral Res. 2011, 92, 187-194. 10.1016/j.antiviral.2011.07.016
294. H. Sun, J. R. Abbott, and W. R. Roush, “Stereoselective Synthesis of a Model C(18)-C(35) Spiroketal Fragment of Integramycin,” Org. Lett. 2011, 13, 2734. 10.1021/ol200834p
293. P. Nuhant, J. Kister, R. Lira, A. Sorg and W. R. Roush, “Development of a Double Allylboration Reagent Targeting 1,5-syn-(E)-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin,” Tetrahedron 2011, 67, 6497. (invited paper for Symposium-in-Print in honor of Prof. S. Omura's Tetrahedron Prize). Corrigendum: 2012, 68, 774.10.1016/j.tet.2011.06.008
292. L.A. Solt, N. Kumar, P. Nuhant, Y. Wang, J. L. Lauer, J. Liu, M. Istrate, T. M. Kamenecka, W. R. Roush, D. Vidovic, S. C. Schurer, J. Xu, G. Wagoner, P. D. Drew, P. R. Griffin and T. P. Burris, "Inhibition of the TH17 Differentiation and Suppression of Autoimmunity by a Selective Synthetic ROR Ligand," Nature 2011, 472, 491. 10.1038/nature10075
291. M. Chen and W. R. Roush, “Enantioselective Syntheses of syn- and antiI- β-Hydroxyallylsilanes via Allene Hydroboration-Aldehyde Allylboration Reactions,” Org. Lett. 2011, 13, 1992. 10.1021/ol200392u
290. M. Chen and W. R. Roush, “Enantioconvergent Hydroboration of a Racemic Allene: Enantioselective Synthesis of (E)-d- Stannyl-anti-Homoallylic Alcohols via Aldehyde Crotylboration,” J. Am. Chem. Soc. 2011, 133, 5744. 10.1021/ja2010187
289. J. Kister, P. Nuhant, R. Lira, A. Sorg and W. R. Roush, “Enantio- and Diastereoselective Syntheses of (E)-1,5-syn-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin,”Org. Lett. 2011, 13 , 1868. 10.1021/ol2003836
288. S. A. Busby, N. Kumar, D. S. Kuruvilla, M. A. Istrate, J. J. Conkright, Y. Wang, T. M. Kamenecka, M. D. Cameron, W. R. Roush, T. P. Burris and P. R. Griffin, “Identification of a Novel Non-retinoid Pan Inverse Agonist of the Retinoic Acid Receptors,” ACS Chem. Biol. 2011, ASAP. 10.1021/cb100396s
287. Y. Lee, J. Y. Choi, H. Fu, C. Harvey, S. Ravindran, W. Roush, J. C. Boothroyd, and C. Khosla, “Chemistry and Biology of Macrolide Antiparasitic Agents,” J. Med. Chem., 2011, 54, 2792. 10.1021/jm101593u
286. P. Stewart, M. Chen, W. R. Roush, and D. Ess, “Thermodynamic Control of 1,3-Boratropic Shifts of α- and γ-Stannyl-Substituted Allylboranes: Hyperconjugation Outweighs Steric Effects,” Org. Lett. 2011, 13, 1478. 10.1021/ol2001599
285. N. Kumar, D. J. Kojetin, L. A. Solt, K. G. Kumar, P. Nuhant, D. R. Duckett, M. D. Cameron, A. A. Butler, W. R. Roush, P. R. Griffin and T. P. Burris, “Identification of SR3335 (ML176), a Synthetic RORa Selective Inverse Agonist,” ACS Chem. Biol. 2011, 6, 218. 10.1021/cb1002762
284. H. Sun and W. R. Roush, “Synthesis of (S,S)-Diisopropyl Tartrate (E)-Crotylboronate and Its Reaction with Aldehydes: (2R,3R,4R)-1,2-Dideoxy-2-ethenyl-4,5-O-(1-methylethylidene)-xylitol,” Org. Synth. 2011, 88, 181.
283. H. Sun and W. R. Roush, “Synthesis of (+)-B-Allyldiisopinocampheylborane and Its Reaction with Aldehydes: (2R, 3R)-1-(tert-Butyldiphenylsilyloxy)-2-methylhex-5-en-3-ol,” Org. Synth. 2011, 88, 87.
282. J. T. Halvorsen and W. R. Roush, “Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones,” Tetrahedron Lett. 2011, in press (invited manuscript for special issue in honor of Prof. Harry Wasserman’s 90th birthday). 10.1016/j.tetlet.2010.10.111
