Transplant Genomics Collaborative Group

National Institute of Allergy and Infectious Diseases

Grant Number: 1U19AI063603-01

Welcome to the Genomics for Kidney Transplantation Project . The Project was established in 2004 under a National Institute of Allergy and Infectious Diseases Program Project Grant. The aim of the Transplant Genomics Collaborative Group is to apply the developing technologies for gene expression profiling (Project 1), proteomics (Project 2) and complex trait genetics (Project 3) to advance our understanding of kidney transplantation in the context of both its clinical problems and the basic biology of transplantation. Our view is that this "systems biology" approach will be valuable in the advancement of the understanding of problems associated with kidney transplantation. These efforts are supported by a group of collaborators with expertise in all three scientific areas, as well as expertise in clinical kidney transplantation and bioinformatics and statistics.

Gene expression profiling is performed by Project 1, headed by Dr. Daniel Salomon and Steve Head (DNA Array Core Facility) at the Scripps Research Institute. Proteomics profiling is done by Project 2 , headed by Dr. John Yates also at the Scripps Research Institute. SNP genotyping is done by Project 3 headed by Dr. Pui-Yan Kwok at UCSF. Bioinformatics and statistics support is headed by Dr. Steve Horvath at UCLA. More detailed information about each of these Projects can be found at the Transplant Genomics Homepage. More information about the leaders of these projects and their individual research laboratories can be found using the links to the left.