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Molecular Medicine

Faculty

Hiroshi Asahara, M.D., Ph.D.

Professor of MEM
Department of Molecular Medicine
California Campus
Laboratory Website
asahara@scripps.edu
(858) 784-9026

Research Focus

As a molecular biologist and orthopedic surgeon, Dr. Asahara's research focuses on examining the precise mechanism of chromatin-dependent gene regulation related to limb development. Combining these new findings in molecular and developmental biology, with clinical research in the field of locomotive science, our aim is to develop innovative new therapies that will benefit patients with arthritis, bone tumor and spinal cord injuries.

Awards & Professional Activities

Arthritis National Research Foundation Grant Award, 2000
Hulda Irene Arthritis Investigator Award, 2002
Arthritis Investigator Award, Arthritis Foundation, 2002
Arthritis Foundation, Molecular Immunology Study Section, 2004
Ad Hoc member, NIH MOSS Study Section, NIH SBDD Study Section, 2004

Selected References

Y. Kawakami, M. Tsuda, S. Takahashi, N. Taniguchi, C.R. Esteban, M. Zemmyo,T. Furumatsu, M. Lotz, J.C. Belmonte, H. Asahara. "Transcriptional coactivator PGC-1a regulates chondrogenesis via association with Sox9." Proc Natl Acad Sci, USA, 102(7), 2414-9, 2005.

T. Furumatsu, M. Tsuda, N. Taniguchi Y. Tajima, H. Asahara. "Smad3 induces chondrogenesis through the activation of SOX9 via CBP/p300 recruitment." J Biol Chem, 280(9), 8843-350, 2005.

Y. Kawakami, J. Rodriguez-Leon, C. M. Koth, D. Buscher, T. Itoh, A. Raya, J. K. Ng, C. Rodriguez Esteban, S. Takahashi, D. Henrique, M. F. Schwarz, H. Asahara, J. C. Belmonte. "MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb." Nat Cell Biol, 5(6) 513-9, 2003.

M. Tsuda, S. Takahashi, Y. Takahashi, H. Asahara. " Transcriptional co-activators CBP/p300 regulate chondrocyte specific gene expression via association with Sox9." J Biol Chem, 278(29) 27224-9, 2003.

Molecular Medicine Seminar Series

CA Faculty

Asahara, Hiroshi
Balch, William E.
Boddy, Michael
Buxbaum, Joel
Catz, Sergio
Conti, Bruno
Cravatt, Benjamin
D'Lima, Darryl
DerMardirossian, Celine
Deryugina, Elena
Elias, Darlene
Encalada, Sandra
Felding, Brunhilde
Fowler, Velia
Friedlander, Martin
Gerace, Larry
Gottesfeld, Joel
Griffin, John
Hanneken, Anne
Heeb, Mary Jo
Henderson, Scott
Hoch, James
Joazeiro, Claudio
Johnson, Eric
Kanaji, Taisuke
Kay, Steve
Kelly, Jeffery
Koziol, James
Lamia, Katja
Lazzerini Denchi, Eros
Lipton, Stuart
Loring, Jeanne F.
Loskutoff, David
Lotz, Martin
Makarenkova, Helen P.
Mc Millan, Robert
Miles, Lindsey
Milner, Richard
Modena, Brian
Mosnier, Laurent
Paulson, James C.
Perego, Marta
Petrascheck, Michael
Pollard, Kenneth Michael
Quigley, James P.
Reed, Steven
Roberts, Edward
Rosen, Hugh
Ruggeri, Zaverio
Russell, Paul
Saez, Enrique
Smider, Vaughn
Srinivasan, Supriya
Steinhubl, Steven
Sutcliffe, J.
Tan, Eng
Topol, Eric
Vanderklish, Peter
Vogt, Peter K.
Waalen, Jill
Wiseman, Luke
Wittenberg, Curt
Wolan, Dennis W.
Wu, Peng
Wu, Xiaohua
Yang, Xiang-Lei
Yates III, John


FL Faculty

Bohn, Laura M.
Cameron, Michael
Duckett, Derek
Gill, Matt
Griffin, Patrick
Hansen, Scott
Kamenecka, Theodore
Kissil, Joseph
Luo, Junli
McDonald, Patricia
Miller, Courtney
Niedernhofer, Laura
Phinney, Donald G.
Robbins, Paul
Scampavia, Louis
Schimmel, Paul
Smith, Roy
Spicer, Timothy


Affiliated Faculty

Cline, Hollis
Kojetin, Douglas
Lairson, Luke
Paegel, Brian
Rumbaugh, Gavin
Shen, Ben
Solt, Laura A
Su, Andrew
Wu, Chunlei


Adjunct Faculty