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Pascal Poignard, MD, PhD

Professor Adjunct
Department of Immunology and Microbiology
California Campus
Scripps VIVO Scientific Profile
poignard@scripps.edu
(858) 784-9193

Professional Experience

2016-2017 Professor Adjunct, Immunology and Microbial Science (IMS), The Scripps Research Institute
1996-2016 Professor, Immunology and Microbial Science (IMS), The Scripps Research Institute

Selected References

All Publications

Rantalainen, K., Berndsen, Z. T., Murrell, S., Cao, L., Omorodion, O., Torres, J. L., Wu, M. Y., Umotoy, J., Copps, J., Poignard, P., Landais, E., Paulson, J. C., et al. Co-evolution of HIV envelope and apex-targeting neutralizing antibody lineage provides benchmarks for vaccine design. (2018). Cell Reports, 23(11), 3249-3261. PMCID: PMC6019700.

Landais, E., Murrell, B., Briney, B., Murrell, S., Rantalainen, K., Berndsen, Z. T., Ramos, A., Wickramasinghe, L., Smith, M. L., Eren, K., de Val, N., Wu, M., et al. HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage. (2017). Immunity, 47(5), 990-1003. PMCID: PMC5736302.

Wagner, G. A., Landais, E., Caballero, G., Phung, P., Pond, S. L. K., Poignard, P., Richman, D. D., Little, S. J. & Smith, D. M. Intrasubtype B HIV-1 superinfection correlates with delayed neutralizing antibody response. (2017). Journal of Virology, 91(17), UNSP e00475-17.

Nandin, I. S., Fong, C., Deantonio, C., Torreno-Pina, J. A., Pecetta, S., Maldonado, P., Gasparrini, F., Ordovas-Montanes, J., Kazer, S. W., Kjaer, S., Borley, D. W., Nair, U., et al. Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. (2017). Journal of Experimental Medicine, 214(8), 2471-2490. PMCID: PMC5551578.

Dugast, A. S., Arnold, K., Lofano, G., Moore, S., Hoffner, M., Simek, M., Poignard, P., Seaman, M., Suscovich, T. J., Pereyra, F., Walker, B. D., Lauffenburger, D., et al. Virus-driven inflammation is associated with the development of bNAbs in spontaneous controllers of HIV. (2017). Clinical Infectious Diseases, 64(8), 1098-1104.

Sok, D., Pauthner, M., Briney, B., Lee, J. H., Saye-Francisco, K. L., Hsueh, J., Ramos, A., Le, K. M., Jones, M., Jardine, J. G., Bastidas, R., Sarkar, A., et al. A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans. (2016). Immunity, 45(1), 31-45. PMCID: PMC4990068.

Landais, E., Huang, X., Havenar-Daughton, C., Murrell, B., Price, M. A., Wickramasinghe, L., Ramos, A., Bian, C. B., Simek, M., Allen, S., Karita, E., Kilembe, W., et al. Broadly neutralizing antibody responses in a large longitudinal Sub-Saharan HIV primary infection cohort. (2016). PLoS Pathogens, 12. PMCID: PMC4713061.

Havenar-Daughton, C., Lindqvist, M., Heit, A., Wu, J. E., Reiss, S. M., Kendric, K., Belanger, S., Kasturi, S. P., Landais, E., Akondy, R. S., McGuire, H. M., Bothwell, M., et al. CXCL13 is a plasma biomarker of germinal center activity. (2016). Proceedings of the National Academy of Sciences of the United States of America, 113(10), 2702-2707. PMCID: PMC4790995.

MacLeod, D. T., Choi, N. M., Briney, B., Garces, F., Ver, L. S., Landais, E., Murrell, B., Wrin, T., Kilembe, W., Liang, C. H., Ramos, A., Bian, C. B., et al. Early antibody lineage diversification and independent limb maturation lead to broad HIV-1 neutralization targeting the Env high-mannose patch. (2016). Immunity, 44(5), 1215-1226. PMCID: PMC5003182.

Krumm, S. A., Mohammed, H., Le, K. M., Crispin, M., Wrin, T., Poignard, P., Burton, D. R. & Doores, K. J. Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies. (2016). Retrovirology, 13. PMCID: PMC4736637.