Associate Professor, Department of Cancer Biology
Faculty, Graduate Program
The research in Luo's lab focuses on mechanistic and translational research in molecular signaling that connects epigenetic factors with genetic events during tumor genesis, progression and metastasis. Specifically, Luo's lab is working on how epigenetic signaling regulates cancer initial cells self-renewal and trans-differentiation.
Ph.D., Oncology and Cancer Biology, Hunan Medical University, 1997
M.D., Clinical Medical Science, Hunan Medical University, 1989
2008-2014 Assistant Professor, Cancer Biology, The Scripps Research Institute
2002-2008 Postdoctoral Fellow with Dr. Michael Karin, School of Medicine, University of California, San Diego
1999-2002 Visiting Scientist with Dr. Monica Hollstein and Dr. Zhao-Qi Wang, German Cancer Research Center
1998-1999 Doctor in Charge / Lecturer, Department of Head and Neck Cancer, Hunan Medical University
1997-1998 IARC Fellow with Dr. Monica Hollstein, German Cancer Research Center
Wang, G. G., Song, J., Wang, Z., Dormann, H. L., Casadio, F., Li, H., Luo, J-L., Patel, D. J., and Allis, C. D. 2009. Haematopoietic malignancies initiated by dysregulation of a chromatin-binding PHD finger. Nature, May 19.
Kim, S., Takahashi, H., Lin, W-W., Descargues, P., Grivennikov, S., Kim Y., Luo, J-L., Karin M. 2009. Carcinoma Produced Factors Activate Myeloid Cells via TLR2 to Stimulate Metastasis.Nature, 457:102-6.
Matsuzawa, A., Tseng, P-H., Vallabhapurapu, S., Luo, J-L., Zhang, W., Wang, H., Vignali, D. A. A., Gallagher, E., Karin, M. (2008) Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.Science, 321:663-8.
Luo, J-L., Tan, W., Ricono, J. M., Korchynskyi, O., Zhang, M., Gonias, S. L., Cheresh D. A., and Karin, M. (2007) Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature, 446: 690-4.