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Michel Le Moal, M.D., Ph.D.

Professor Adjunct
Department of Neuroscience
California Campus
Scripps VIVO Scientific Profile
mlemoal@scripps.edu
(858) 784-9724

Education

Ph.D., University of Bordeaux Segalen (Bordeaux 2) 1974
University of Bordeaux Segalen (Bordeaux 2) 1968
University of Bordeaux Segalen (Bordeaux 2) 1967
M.D., University of Bordeaux Segalen (Bordeaux 2) 1964
M.S. (Biological Sciences), University of Bordeaux Segalen (Bordeaux 2) 1962
University of Bordeaux Segalen (Bordeaux 2) 1961
M.D., University of Bordeaux Segalen (Bordeaux 2) 1962

Professional Experience

1998-2017 Professor Adjunct, Committee on the Neurobiology of Addictive Disorders (CNAD), The Scripps Research Institute
1974-1976 Postdoctoral Fellow, California Institute of Technology

Selected References

All Publications

George, O., Le Moal, M. & Koob, G. F. Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems. (2012). Physiology and Behavior, 106(1), 58-64. PMCID: PMC3288230.

George, O., Vallee, M., Vitiello, S., Le Moal, M., Piazza, P. V. & Mayo, W. Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats. (2010). Biological Psychiatry, 68(10), 956-963. PMCID: PMC2936666.

Koob, G. F. & Le Moal, M. Neurobiological mechanisms for opponent motivational processes in addiction. (2008). Philosophical Transactions of the Royal Society B-Biological Sciences, 363(1507), 3113-3123. PMCID: PMC2607326.

Le Moal, M. & Koob, G. F. Drug addiction: Pathways to the disease and pathophysiological perspectives. (2007). European Neuropsychopharmacology, 17(6-7), 377-393.

Rabat, A., Bouyer, J. J., George, O., Le Moal, M. & Mayo, W. Chronic exposure of rats to noise: relationship between long-term memory deficits and slow wave sleep disturbances. (2006). Behavioural Brain Research, 171(2), 303-312.

Lemaire, V., Billard, J. M., Dutar, P., George, O., Piazza, P. V., Epelbaum, J., Le Moal, M. & Mayo, W. Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress. (2006). European Journal of Neuroscience, 23(12), 3368-3374.

George, O., Vallee, M., Le Moal, M. & Mayo, W. Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. (2006). Psychopharmacology, 186(3), 402-413.

George, O., Parducz, A., Dupret, D., Kharouby, M., Le Moal, M., Piazza, P. V. & Mayo, W. Smad-dependent alterations of PPT cholinergic neurons as a pathophysiological mechanism of age-related sleep-dependent memory impairments. (2006). Neurobiology of Aging, 27(12), 1848-1858.

Vallee, M., George, O., Vitiello, S., Le Moal, M. & Mayo, W. New insights into the role of neuroactive steroids in cognitive aging. (2004). Experimental Gerontology, 39(11-12), 1695-1704.

Darbra, S., George, O., Bouyer, J. J., Piazza, P. V., Le Moal, M. & Mayo, W. Sleep-wake states and cortical synchronization control by pregnenolone sulfate into the pedunculopontine nucleus. (2004). Journal of Neuroscience Research, 76(5), 742-747.