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Mansun Law, Ph.D.

Associate Professor
Department of Immunology and Microbiology
California Campus
Laboratory Website
Scripps VIVO Scientific Profile
mlaw@scripps.edu
(858) 784-7033

Scripps Research Joint Appointments

Faculty, Graduate Program

Education

D.Phil., Virology, University of Oxford, 2001

Professional Experience

2014-2017 Associate Professor, Immunology and Microbial Science (IMS), The Scripps Research Institute
2008-2014 Assistant Professor, Immunology and Microbial Science (IMS), The Scripps Research Institute
2004-2008 Research Associate and Senior Research Associate with Dr. Dennis R. Burton, Immunology and Microbial Science (IMS), The Scripps Research Institute
2001-2004 Postdoctoral Fellow with Dr. Geoffrey L. Smith, Imperial College London

Selected References

All Publications

Velazquez-Moctezuma, R., Law, M., Bukh, J. & Prentoe, J. Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A. (2017). PLoS Pathogens, 13.

Morris, C. D., Azadnia, P., de Val, N., Vora, N., Honda, A., Giang, E., Saye-Francisco, K., Cheng, Y. S., Lin, X., Mann, C. J., Tang, J., Sok, D., et al. Differential antibody responses to conserved HIV-1 neutralizing epitopes in the context of multivalent scaffolds and native-like gp140 trimers. (2017). mBio, 8(1), e00036-17. PMCID: PMC5347340.

Logan, M., Law, J., Wong, J. A., Hockman, D., Landi, A., Chen, C., Crawford, K., Kundu, J., Baldwin, L., Johnson, J., Dahiya, A., LaChance, G., et al. Native folding of a recombinant gpE1/gpE2 heterodimer vaccine antigen from a precursor protein fused with Fc IgG. (2017). Journal of Virology, 91. PMCID: PMC5165201.

Prentoe, J., Velazquez-Moctezuma, R., Foung, S. K. H., Law, M. & Bukh, J. Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity. (2016). Hepatology, 64(6), 1881-1892. PMCID: PMC5115964.

O'Shea, D., Law, J., Egli, A., Douglas, D., Lund, G., Forester, S., Lambert, J., Law, M., Burton, D. R., Tyrrell, D. L. J., Houghton, M., Humar, A., et al. Prevention of hepatitis C virus infection using a broad cross-neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate. (2016). Liver Transplantation, 22(3), 324-332. PMCID: PMC4769112.

Kong, L., Lee, D. E., Kadam, R. U., Liu, T., Giang, E., Nieusma, T., Garces, F., Tzarum, N., Woods Jr., V. L., Ward, A. B., Li, S., Wilson, I. A., et al. Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen. (2016). Proceedings of the National Academy of Sciences of the United States of America, 113(45), 12768-12773. PMCID: PMC5111675.

Fusil, F., Calattini, S., Amirache, F., Mancip, J., Costa, C., Robbins, J. B., Douam, F., Lavillette, D., Law, M., Defrance, T., Verhoeyen, E., Cosset, F. L. A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status. (2015). Molecular Therapy, 23(11), 1734-1747. PMCID: PMC4817946.

He, L., Cheng, Y., Kong, L., Azadnia, P., Giang, E., Kim, J., Wood, M. R., Wilson, I. A., Law, M. & Zhu, J. Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding. (2015). Scientific Reports, 5, 12501. PMCID: PMC4533164.

Kong, L., Jackson, K. N., Wilson, I. A. & Law, M. Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design. (2015). Current Opinion in Virology, 11, 148. PMCID: PMC4507806.

Law, M. Editorial overview: Preventive and therapeutic vaccines (B cell epitope vaccine). (2015). Current Opinion in Virology, 11, viii. PMCID: PMC4501630.