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Lawrence Kline, DO

Associate Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 554-8845

Professional Experience

2006-2017 Associate Professor Adjunct, Molecular and Experimental Medicine (MEM), The Scripps Research Institute

Selected References

All Publications

Chuang, T. H., Lee, J., Kline, L., Mathison, J. C. & Ulevitch, R. J. Toll-like receptor 9 mediates cpg-DNA signaling. (2002). Journal of Leukocyte Biology, 71(3), 538-544.

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., Gocayne, J. D., Amanatides, P., et al. The sequence of the human genome. (2001). Science, 291(5507), 1304-1351.

Fearns, C., Kline, L., Gram, H., Di Padova, F., Zurini, M., Han, J. & Ulevitch, R. J. Coordinate activation of endogenous p38 alpha, beta, gamma, and delta by inflammatory stimuli. (2000). Journal of Leukocyte Biology, 67(5), 705-711.

Arbibe, L., Mira, J. P., Teusch, N., Kline, L., Guha, M., Mackman, N., Godowski, P. J., Ulevitch, R. J. & Knaus, U. G. Toll-like receptor 2-mediated nf-kappa b activation requires a raci-dependent pathway. (2000). Nature Immunology, 1(6), 533-540.

Pugin, J., Kravchenko, V. V., Lee, J. D., Kline, L., Ulevitch, R. J. & Tobias, P. S. Cell activation mediated by glycosylphosphatidylinositol-anchored or transmembrane forms of CD14. (1998). Infection and Immunity, 66(3), 1174-1180. PMCID: PMC108031.

Schiff, D. E., Kline, L., Soldau, K., Lee, J. D., Pugin, J., Tobias, P. S. & Ulevitch, R. J. Phagocytosis of gram-negative bacteria by a unique cd14-dependent mechanism. (1997). Journal of Leukocyte Biology, 62(6), 786-794.

Kravchenko, V. V., Steinemann, S., Kline, L., Feng, L. L. & Ulevitch, R. J. Endotoxin tolerance is induced in Chinese hamster ovary cell lines expressing human CD14. (1996). Shock, 5(3), 194-201.

Tobias, P. S., Soldau, K., Kline, L., Lee, J. D., Kato, K., Martin, T. P. & Ulevitch, R. J. Cross-linking of lipopolysaccharide (lps) to cd14 on thp-1 cells mediated by lps-binding protein. (1993). Journal of Immunology, 150(7), 3011-3021.

Ulevitch, R. J., Kline, L., Schreiber, R. D., Pingel, J., Amaldi, I., Reith, W. & Mach, B. Hyperexpression of interferon-gamma-induced mhc class-ii genes associated with reorganization of the cytoskeleton. (1991). American Journal of Pathology, 139(2), 287-296. PMCID: PMC1886081.