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Masanori Isogawa, M.D.

Assistant Professor Adjunct
Department of Immunology and Microbiology
California Campus
Scripps VIVO Scientific Profile
masanori@scripps.edu
(858) 784-2247

Professional Experience

2013-2017 Assistant Professor Adjunct, Immunology and Microbial Science (IMS), The Scripps Research Institute
2001-2013 Assistant Professor, Immunology and Microbial Science (IMS), The Scripps Research Institute

Selected References

All Publications

Guidotti, L. G., Inverso, D., Sironi, L., Di Lucia, P., Fioravanti, J., Ganzer, L., Fiocchi, A., Vacca, M., Aiolfi, R., Sammicheli, S., Mainetti, M., Cataudella, T., et al. Immunosurveillance of the liver by intravascular effector CD8(+) T cells. (2015). Cell, 161(3), 486-500.

Sitia, G., Iannacone, M., Aiolfi, R., Isogawa, M., van Rooijen, N., Scozzesi, C., Bianchi, M. E., von Andrian, U. H., Chisari, F. V. & Guidotti, L. G. Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. (2011). PLoS Pathogens, 7, e1002061. PMCID: PMC3107209.

Bissig, K. D., Wieland, S. F., Tran, P., Isogawa, M., Le, T. T., Chisari, F. V. & Verma, I. M. Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. (2010). Journal of Clinical Investigation, 120(3), 924-930. PMCID: PMC2827952.

Yang, P. L., Althage, A., Chung, J., Maier, H., Wieland, S., Isogawa, M. & Chisari, F. V. Immune effectors required for hepatitis B virus clearance. (2010). Proceedings of the National Academy of Sciences of the United States of America, 107(2), 798-802. PMCID: PMC2818933.

Chisari, F. V., Isogawa, M. & Wieland, S. F. Pathogenesis of hepatitis B virus infection. (2010). Pathologie Biologie, 58(4), 258-266. PMCID: PMC2888709.

Takahashi, K., Asabe, S., Wieland, S., Garaigorta, U., Gastaminza, P., Isogawa, M. & Chisari, F. V. Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection. (2010). Proceedings of the National Academy of Sciences of the United States of America, 107(16), 7431-7436. PMCID: PMC2867703.

Cheng, G., Montero, A., Gastaminza, P., Whitten-Bauer, C., Wieland, S. F., Isogawa, M., Fredericksen, B., Selvarajah, S., Gallay, P. A., Ghadiri, M. R. & Chisari, F. V. A virocidal amphipathic alpha-helical peptide that inhibits hepatitis C virus infection in vitro. (2008). Proceedings of the National Academy of Sciences of the United States of America, 105(8), 3088-3093. PMCID: PMC2268589.

Iannacone, M., Sitia, G., Isogawa, M., Whitmire, J. K., Marchese, P., Chisari, F. V., Ruggeri, Z. M. & Guidotti, L. G. Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus. (2008). Proceedings of the National Academy of Sciences of the United States of America, 105(2), 629-634. PMCID: PMC2206587.

Maier, H., Isogawa, M., Freeman, G. J. & Chisari, F. V. PD-1 : PD-L1 interactions contribute to the functional suppression of virus-specific CD8(+) T lymphocytes in the liver. (2007). Journal of Immunology, 178(5), 2714-2720.

Zhong, J., Gastaminza, P., Chung, J., Stamataki, Z., Isogawa, M., Cheng, G. F., McKeating, J. A. & Chisari, F. V. Persistent hepatitis C virus infection in vitro: Coevolution of virus and host. (2006). Journal of Virology, 80(22), 11082-11093.