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Daniel Hoyer, PhD

Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 784-8402


D.Sc. (Pharmacology), Louis Pasteur University 1981
Ph.D. (Pharmacology), Louis Pasteur University 1981

Professional Experience

2004-2017 Professor Adjunct, Chemical Physiology, The Scripps Research Institute
1983-2012 Director, Novartis leading scientist, Neuropsychiatry, Neuroscience research, Novartis
2003-2005 Director of Translational Biology, Neuropsychiatry, Novartis
2002-2005 Member Core Management Team, Neuroscience Research, NIBR Basel, Novartis
1981-1983 Postdoctoral Research Associate, Medical School, Pharmacology, University of Pennsylvania

Selected References

All Publications

Kenny, P. J., Hoyer, D. & Koob, G. F. Animal models of addiction and neuropsychiatric disorders and their role in drug discovery: honoring the legacy of Athina Markou. (2018). Biological Psychiatry, 83(11), 940-946.

Curtis, M. J., Alexander, S., Cirino, G., Docherty, J. R., George, C. H., Giembycz, M. A., Hoyer, D., Insel, P. A., Izzo, A. A., Ji, Y., MacEwan, D. J., Sobey, C. G., et al. Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers. (2018). British Journal of Pharmacology, 175(7), 987-993. PMCID: PMC5843711.

Velkov, T., Dai, C., Ciccotosto, G. D., Cappai, R., Hoyer, D. & Li, J. Polymyxins for CNS infections: Pharmacology and neurotoxicity. (2018). Pharmacology & Therapeutics, 181, 85.

Dai, C., Ciccotosto, G. D., Cappai, R., Wang, Y., Tang, S., Hoyer, D., Schneider, E. K., Velkov, T. & Xiao, X. Rapamycin confers neuroprotection against colistin-induced oxidative stress, mitochondria dysfunction, and apoptosis through the activation of autophagy and mTOR/Akt/CREB signaling pathways. (2018). ACS Chemical Neuroscience, 9(4), 824-837.

Schneider-Futschik, E. K., Paulin, O. K. A., Hoyer, D., Roberts, K. D., Ziogas, J., Baker, M. A., Karas, J., Li, J. & Velkov, T. Sputum active polymyxin lipopeptides: activity against cystic fibrosis pseudomonas aeruginosa isolates and their interactions with sputum biomolecules. (2018). ACS Infectious Diseases, 4(5), 646-655. PMCID: PMC5952261.

Hoyer, D. 5-HT receptor nomenclature: Naming names, does it matter? A tribute to Maurice Rapport. (2017). ACS Chemical Neuroscience, 8(5), 908-919.

Palacios, J. M., Pazos, A. & Hoyer, D. A short history of the 5-HT2C receptor: From the choroid plexus to depression, obesity and addiction treatment. (2017). Psychopharmacology, 234(9-10), 1395-1418.

Jacobson, L. H., Hoyer, D., Fehlmann, D., Bettler, B., Kaupmann, K. & Cryan, J. F. Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABA(B1a) but not GABA(B1b) subunit isoforms. (2017). Psychopharmacology, 234(9-10), 1511-1523.

Liddelow, S. & Hoyer, D. Astrocytes: adhesion molecules and immunomodulation. (2016). Current Drug Targets, 17(16), 1871-1881.

Andreetta, F., Carboni, L., Grafton, G., Jeggo, R., Whyment, A. D., van den Top, M., Hoyer, D., Spanswick, D. & Barnes, N. M. Hippocampal 5-HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated-neurotransmission in vitro and in vivo. (2016). British Journal of Pharmacology, 173(9), 1438-1451. PMCID: PMC4831309.