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Luigi De Marco, PhD

Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 784-8195


M.D., University of Padova, Medical School 1972
M.D., University of Padova, Laboratory Medicine Residency Program 1986
M.D., University of Padova, Nuclear Medicine Residency Program 1978
M.D., University of Padova, Hematology Residency Program 1975

Professional Experience

2013-2017 Professor Adjunct, Molecular and Experimental Medicine (MEM), The Scripps Research Institute
2002-2012 Director, Department of Laboratory Diagnostics and Cellular Therapy, National Cancer Institute CRO Aviano
1999-2012 Professor of Clinical Pathology, University of Udine
1989-2012 Director of the Blood Bank and Clinical Pathology Laboratory, National Cancer Institute CRO Aviano
1980-1989 Associate Director, Azienda Ospedaliera Pordenone
1987-1988 Visiting Scientist, The Scripps Research Institute
1978-1980 Visiting Scientist, Thomas Jefferson University
1976-1978 Assistant Director of the Blood Bank and Coagualtion Laboratory, Azienda Ospedaliera Pordenone
1974-1975 Medical Officer, Italian Army
1973-1974 Assistant Medical Director, Azienda Ospedaliera Pordenone S. Maria degli Angeli
1972-1973 Intern, University of Padova

Selected References

All Publications

Malara, A., Gruppi, C., Celesti, G., Abbonante, V., Viarengo, G., Laghi, L., De Marco, L., Muro, A. F. & Balduini, A. Alternatively spliced fibronectin extra domain A is required for hemangiogenic recovery upon bone marrow chemotherapy. (2018). Haematologica, 103(2), E42-E45. PMCID: PMC5792283.

Mazzucato, M., Cozzi, M. R., Battiston, M., Jandrot-Perrus, M., Mongiat, M., Marchese, P., Kunicki, T. J., Ruggeri, Z. M. & De Marco, L. Distinct spatio-temporal Ca(2+) signaling elicited by integrin alpha 2 beta 1 and glycoprotein VI under flow. (2009). Blood, 114(13), 2793-2801. PMCID: PMC2756134.

Casonato, A., De Marco, L., Gallinaro, L., Sztukowska, M., Mazzuccato, M., Battiston, M., Pagnan, A. & Ruggeri, Z. M. Altered von Willebrand factor subunit proteolysis and multimer processing associated with the Cys2362Phe mutation in the B2 domain. (2007). Thrombosis and Haemostasis, 97(4), 527-533.

Mazzucato, M., Cozzi, M. R., Pradella, P., Ruggeri, Z. M. & De Marco, L. Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow. (2004). Blood, 104(10), 3221-3227.

Kasirer-Friede, A., Cozzi, M. R., Mazzucato, M., De Marco, L., Ruggeri, Z. M. & Shattil, S. J. Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. (2004). Blood, 103(9), 3403-3411.

Mazzucato, M., Pradella, P., Cozzi, M. R., De Marco, L. & Ruggeri, Z. M. Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ib alpha mechanoreceptor. (2002). Blood, 100(8), 2793-2800.

Mazzucato, M., De Marco, L., Masotti, A., Pradella, P., Bahou, W. F. & Ruggeri, Z. M. Characterization of the initial alpha-thrombin interaction with glycoprotein Ib alpha in relation to platelet activation. (1998). Journal of Biological Chemistry, 273(4), 1880-1887.