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Sydney Brenner, PhD

Professor of Genetics
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 784-9798

Scripps Research Joint Appointments

Profesor of Genetics, Department of Chemistry


M.Sc., Medicine and Science, University of Witwatersrand, South Africa, 1947
D.Phil., Chemistry, Oxford University, 1951
MB BCh, University of Witwatersrand, South Africa, 1951

Professional Experience

1979-86 Director, Medical Research Council Laboratory of Molecular Biology, Cambridge, England
1986-91 Director, Medical Research Council Molecular Genetics Unit, Cambridge, England
1996- President and Director of Science, The Molecular Sciences Institute, La Jolla and Berkeley
2000- Distinguished Research Professor, The Salk Institute, La Jolla, USA

Awards & Professional Activities

1965 Fellow of the Royal Society (FRS)
1971 Albert Lasker Medical Research Award
1974 Royal Medal, Royal Society of London
1976 Honorary DSc, University of Chicago
1978 Gairdner Foundation International Award, Canada
1980 Krebs Medal, Federation of European Biochemical Societies
1981 Ciba Medal, Biochemical Society
1985 Foreign Member of Real Academia de Ciencias, Spain
1986 Rosenstiel Award, Brandeis University, USA
1987 Prix Louis Jeantet de Medecine, Switzerland
1987 Harvey Prize, Technion - Israel Institute of Technology
1988 Waterford Bio-Medical Science Award, The Research Institute of Scripps Clinic
1988 External Scientific Member of the Max-Planck Society
1989 Honorary Fellow of the Indian Academy of Sciences
1989 Honorary Member of the Chinese Society of Genetics, Taiwan
1990 Kyoto Prize
1991 Gairdner Foundation International Award, Canada
1992 King Faisal International Prize for Science, King Faisal Foundation
1992 Associe Etranger, Académie des Sciences, Paris, France
2000 Albert Lasker Award for Special Achievement in Medical Science
2001 Novartis Drew Award In Biomedical Research
2002 Nobel Prize in Physiology or Medicine

Selected References

All Publications

Lerner, R. A. & Brenner, S. DNA-encoded compound libraries as open source: A powerful pathway to new drugs. (2017). Angewandte Chemie-International Edition, 56(5), 1164-1165.

Albertin, C. B., Simakov, O., Mitros, T., Wang, Z. Y., Pungor, J. R., Edsinger-Gonzales, E., Brenner, S., Ragsdale, C. W. & Rokhsar, D. S. The octopus genome and the evolution of cephalopod neural and morphological novelties. (2015). Nature, 524(7564), 220-224. PMCID: PMC4795812.

Bhatia, S., Monahan, J., Ravi, V., Gautier, P., Murdoch, E., Brenner, S., van Heyningen, V., Venkatesh, B. & Kleinjan, D. A. A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. (2014). Developmental Biology, 387(2), 214-228.

Nah, G. S. S., Tay, B. H., Brenner, S., Osato, M. & Venkatesh, B. Characterization of the Runx gene family in a jawless vertebrate, the Japanese lamprey (Lethenteron japonicum). (2014). PLoS One, 9, e113445. PMCID: PMC4236176.

Venkatesh, B., Lee, A. P., Ravi, V., Maurya, A. K., Lian, M. M., Swann, J. B., Ohta, Y., Flajnik, M. F., Sutoh, Y., Kasahara, M., Hoon, S., Gangu, V., et al. Elephant shark genome provides unique insights into gnathostome evolution. (2014). Nature, 505(7482), 174-179. PMCID: PMC3964593.

Brenner, S. Frederick Sanger (1918-2013). (2014). Science, 343(6168), 262-262.

Goh, W. L., Lee, M. Y., Joseph, T. L., Quah, S. T., Brown, C. J., Verma, C., Brenner, S., Ghadessy, F. J. & Teo, Y. N. Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions. (2014). Journal of the American Chemical Society, 136(17), 6159-6162.

Venkatesh, B., Lee, A. P., Ravi, V., Maurya, A. K., Korzh, V., Lim, Z. W., Ingham, P. W., Boehm, T., Brenner, S. & Warren, W. C. On the origin of SCPP genes. (2014). Evolution & Development, 16(3), 125-126.

Venkatesh, B., Ravi, V., Lee, A. P., Warren, W. C. & Brenner, S. Basal vertebrates clarify the evolutionary history of ciliopathy-associated genes Tmem138 and Tmem216. (2013). Molecular Biology and Evolution, 30(1), 62-65. PMCID: PMC3657383.

Mehta, T. K., Ravi, V., Yamasaki, S., Lee, A. P., Lian, M. M., Tay, B. H., Tohari, S., Yanai, S., Tay, A., Brenner, S. & Venkatesh, B. Evidence for at least six Hox clusters in the Japanese lamprey (Lethenteron japonicum). (2013). Proceedings of the National Academy of Sciences of the United States of America, 110(40), 16044-16049. PMCID: PMC3791769.