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Klaus Bister, PhD

Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 784-8079


M.S., Chemistry, University of Cologne, 1971
Ph.D., Biochemistry, University of Cologne, 1973

Professional Experience

Professor Adjunct, The Scripps Research Institute, since 2014
Professor Emeritus of Biochemistry, University of Innsbruck, since 2014
Guest Scientist, The Scripps Research Institute, La Jolla, California, 2001 and 2003
Professor and Chair of Biochemistry, University of Innsbruck, 1994 - 2014
Associate Professor of Biochemistry, University of Cologne, 1988 - 1993
Group Leader, Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, 1982 - 1987
Postdoctoral fellow, 1975 - 1981:
-    Dept. of Microbiology (with Peter Vogt), School of Medicine, University of Southern California, Los Angeles
-    Institute of Virology (with Harald zur Hausen), Medical School, University of Freiburg
-    Dept. of Molecular Biology (with Peter Duesberg), University of California, Berkeley

Selected References

All Publications

Stefan E, Bister K. MYC and RAF: Key effectors in cellular signaling and major drivers in human cancer. Curr. Top. Microbiol. Immunol. 407, 117-151 (2017). PMID: 28466200   DOI: 10.1007/82_2017_4

Raffeiner P, Schraffl A, Schwarz T, Röck R, Ledolter K, Hartl M, Konrat R, Stefan E, Bister K. Calcium-dependent binding of Myc to calmodulin. Oncotarget 8, 3327-3343 (2017). PMID: 27926480

Bister K. Discovery of oncogenes: The advent of molecular cancer research. Proc. Natl. Acad. Sci. USA 112, 15259-15260 (2015). PMID: 26644573

Hart JR, Garner AL, Yu J, Ito Y, Sun M, Ueno L, Rhee J-K, Baksh MM, Stefan E, Hartl M, Bister K, Vogt PK, Janda KD. Inhibitor of MYC identified in a Kröhnke pyridine library. Proc. Natl. Acad. Sci. USA 111, 12556-12561 (2014). PMID: 25114221

Hartl M, Mitterstiller AM, Valovka T, Breuker K, Hobmayer B, Bister K. Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra. Proc. Natl. Acad. Sci. USA 107, 4051-4056 (2010). PMID: 20142507

Hartl M, Nist A, Khan MI, Valovka T, Bister K. Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1). Proc. Natl. Acad. Sci. USA 106, 5604-5609 (2009). PMID: 19297618

Fieber W, Schneider ML, Matt T, Kräutler B, Konrat R, Bister K. Structure, function, and dynamics of the dimerization and DNA binding domain of oncogenic transcription factor v‑Myc. J. Mol. Biol. 307, 1395-1410 (2001). PMID: 11292350

Jansen HW, Rueckert B, Lurz R, Bister K. Two unrelated cell‑derived sequences in the genome of avian leukemia and carcinoma inducing retrovirus MH2. EMBO J. 2, 1969‑1975 (1983). PMID: 6315409

Duesberg PH, Bister K, Vogt PK. The RNA of avian acute leukemia virus MC29. Proc. Natl. Acad. Sci. USA 74, 4320‑4324 (1977). PMID: 200913

Bister K, Hayman MJ, Vogt PK. Defectiveness of avian myelocytomatosis virus MC29: Isolation of long‑term nonproducer cultures and analysis of virus‑specific polypeptide synthesis. Virology 82, 431‑448 (1977). PMID: 199997  -  DOI: 10.1016/0042-6822(77)90017-4