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Faculty
James Hoch
Professor
Department of Molecular and Experimental Medicine
TSRI - 1967
Education
Ph.D., University of Illinois, Urbana 1965
Awards & Activities
Faculty Research Awardee, American Cancer Society
Editorial Board, Molecular Microbiology
Research Focus
The work in the laboratory focuses on the structure and function of signal transduction proteins regulating gene expression for virulence and prokaryotic development in sporulating bacteria.
Selected References
Szurmant, H., Bu, L., Brooks III, C.L. and Hoch, J.A. An essential sensor histidine kinase regulated by TM helix interactions with its auxiliary proteins. PNAS. 105(15):5891-6. 2008
Szurmant, H., White, R.A. and Hoch, J.A. Sensor complexes regulating two-component signal transduction. Curr. Opin. Struct. Biol. 17(6):706-15. 2007
White, R.A., Szurmant, H., Hoch, J.A. and Hwa, T. Features of protein-protein interactions in two-component signaling deduced from genomic libraries. Methods Enzymol. 422:75-101. 2007
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