Getzoff, Elizabeth D.
aims to characterize functionally important protein conformational states by coupling crystallography, spectroscopy, molecular biology and computational analyses, and to apply that knowledge to protein and inhibitor design for key biological processes, including photoactivity, electron transfer, and enzyme catalysis.
Goodin, David B.
is focused on the rational engineering of metalloenzyme catalysts in order to better understand the chemical diversity of natural enzymes and to generate novel catalysts of potential utility.
Noodleman, Louis
uses quantum chemistry and protein electrostatics to investigate the electronic structures and active site mechanisms of redox metalloproteins, such as respiratory iron-sulfur proteins, the nitrogen fixing nitrogenase enzyme, and the iron-oxo dimer enzymes methane monooxygenase and ribonucleotide reductase.
