Getzoff, Elizabeth D.
aims to characterize functionally important protein conformational states by coupling crystallography, spectroscopy, molecular biology and computational analyses, and to apply that knowledge to protein and inhibitor design for key biological processes, including photoactivity, electron transfer, and enzyme catalysis.
Heeb, Mary J.
examines the biochemistry and mechanism of action of novel anticoagulant molecules like protein Z and protein S, which may be valuable targets for intervention in thrombotic and vascular diseases.
Riewald, Matthias
studies signaling of protease-activated receptor 1 and activated protein C in blood coagulation and systemic inflammation.
Romesberg, Floyd Eric
seeks to understand and evolve novel protein function by expanding the genetic code, to understand the molecular basis of DNA damage, repair, and mutagenesis, and to use femtosecond laser pulses to probe protein dynamics.
Siuzdak, Gary E.
is interested in the design and application of mass spectrometry technology including pulsed laser desorption/ionization from silicon surfaces, understanding virus structure/activity, and metabolite profiling.
