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The Department of Chemistry at The Scripps Research Institute (TSRI) was founded in 1989. Today it is a bi-coastal department with faculty at the California (La Jolla) and the Florida (Jupiter) campuses of TSRI. Its mission includes both education and training at the graduate and postdoctoral level and research and development in the chemical and biological sciences. While most research activities within the department focus primarily on biomedical research, a number of efforts are also directed toward nanotechnology, new energy sources, and the environment.

Chemistry aims to understand matter, create new forms of matter, and translate its new discoveries into useful products, as well as provide enabling technologies for other disciplines, including biology and medicine. Chemistry is indispensable as a science, for it provides the ability to understand living systems at the molecular level. Chemistry is central to the drug discovery and development process, providing the molecules that eventually become the medicines that cure and treat disease. Fuels, polymers, plastics, and other high-tech materials are also the products of chemistry. The sophistication of all these products depends on the state of the science of chemistry, particularly its ability to synthesize and understand the nature of molecules and their properties. It is essential to continue to advance the field of chemistry at the fundamental level so as to provide state-of-the-art tools to design, synthesize, and evaluate new functional molecules for specific applications.
In addition to advancing the field of chemistry, faculty in the department are searching for cures for diseases, including cancer, Alzheimer’s and other neurodegenerative diseases, HIV-AIDS and other viral diseases, and tuberculosis and other bacterial infections. Others are developing new technologies for RNA evolution, DNA sequencing, nanomedicine, and stem cell research. Faculty are also active in the areas of total synthesis of natural products and their designed analogs, natural product discovery, biosynthesis, pathway engineering, medicinal chemistry, chemical biology, transition metal catalysis and biocatalysis, peptide and protein chemistry, as well as the discovery of new synthetic strategies and technologies. These and other endeavors aim to advance our fundamental knowledge in chemistry and to apply it for the betterment of mankind and human health.

For further details about the department and the research activities of its faculty, please visit the Chemistry – California and Chemistry – Florida webpages.