SeqFold


Contents

Release 2000, February 2000


1. Introduction

What is SeqFold?
Invoking SeqFold
Running SeqFold
A note about implementation

2. Theory

Predicting protein structure and function
Threading algorithms
SeqFold scoring function
SeqFold alignment method
MultiView: multiple features analysis

3. Methodology

Introduction
Typical steps
Using the default parameters
Changing the default parameter values

4. Tutorial

Leptin hormone fold recognition
Phosphatidylethanolamine binding protein

5. Command Summary

Fold_Search
Parameters
Fold_Browse
Fold_Load
Manage_Profiles

A. References

B. File formats

pseq file format
1d_prf file format
MSI sequence similarity matrix file format
NCBI sequence similarity matrix file format
General sequence similarity matrix file format
inf file format

C. Parameter Key

Absolute
Relative

D. DSC (Discrimination of protein Secondary structure Class)

Disclaimer
Introduction
Input/Output
Basic I/O options
Smoothing options
Removing regions of poor alignment
Miscellaneous options
Methods
Residue propensities and GOR
Other residue based concepts in prediction
Information from aligned sequences
Attribute vectors
Linear discrimination
Post processing
References


Last updated March 15, 2000 at 05:18PM Pacific Standard Time.
Copyright © 2000, Molecular Simulations Inc. All rights reserved.