The Scripps Research Institute - At The Forefront

April 2016

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Focus on:
How One Ebola Survivor Could Be Key to a Cure

Last February, as the Ebola outbreak that killed more than 11,000 people was coming under control, a blood sample from a survivor arrived at a lab in Lebanon, New Hampshire. The team, led by Laura Walker, senior scientist at Adimab, LLC, and an alumna of TSRI's PhD program, immediately began testing for antibodies that could effectively fight Ebola.

In the end, the team found more than 300 Ebola-fighting antibodies that could guide the development of an effective therapeutic or vaccine.

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This image shows a key Ebola virus protein and vulnerable sites where antibodies (in color) can bind and neutralize it.

 

 

 

 

 

TSRI's collaborative approach to research is developing novel treatments for devastating conditions like Ebola and bipolar disorder. Please support this life-saving work.

 

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Assistant Professor Supriya Srinivasan (right), here with Research Associate Emily Witham, the study's first author.

 

milestones in medical science:
Does the Brain Hold the Key to Burning More Fat?

Food intake is known as an important regulator of metabolism. For example, if consumption of food is low, the body burns fat and makes up for missing nutrients. But there's growing evidence that fat burning is more complicated than previously thought.

Now, a new study led by TSRI scientists is the first to show that cues picked up from the environment – in roundworms, specifically the sensing of oxygen by the nervous system – may determine how quickly the intestine burns fat.

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Scripps Florida Research Assistant Courtney MacMullen was first author of the study.

 

Other News:
A Breakthrough to Better Treatments for Bipolar Disorder

Bipolar disorder, a neuropsychiatric disorder characterized by manic episodes intermixed with periods of deep depression, takes a toll not only on patients, but also on their families and communities. It affects nearly eight million Americans, nearly one-third of whom have attempted suicide.

A new study by Scripps Florida scientists has identified specific genetic variations closely associated with increased susceptibility to bipolar disorder and other conditions. The discovery may provide a target for new, more effective therapies to fight this too-often devastating condition.

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Save on Your Taxes Through a Gift of Appreciated Securities

With the tax season nearly behind us, are you looking for another way to lower your future taxes and support TSRI? Transferring securities to the institute not only benefits research, it could also provide you with substantial tax advantages. If you have held securities for more than a year and donate them before they are sold, not only can you deduct their full fair market value on your federal tax return, you can also avoid the capital gains tax that would have been due when you sold them. For more information and details about tax savings with a charitable gift of securities, click here.

 

 

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facts & figures

In past Ebola outbreaks, the death rate has varied from 25 to 90 percent, and there is currently no proven treatment for the virus.

 

 

 

The Scripps Research Institute

 

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