“This result was completely
unexpected when we started this research,” says Professor Joel Buxbaum.
milestones in medical science:
An Unlikely Stress Responder May Protect Against
Currently, one in nine Americans over the age of 65
has Alzheimer's disease, and there is no known cure or effective
treatment. However, in
surprising new findings, TSRI scientists have
discovered that transthyretin (TTR), a
protein that is produced in the liver and some areas of the brain,
can bind together the beta-amyloid proteins associated with
Alzheimer's and ultimately lessen the amount of that protein in the
brains of those with the disease.
The results suggest that drugs that can boost the protein's
production in neurons could one day help ward off Alzheimer's