The Scripps Research Institute - At The Forefront
August 2013 Connect with us:
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Focus on:
Breakthrough in Treating TB

At any moment, about a third of the world's population is infected with tuberculosis (TB). Most is inactive, latent TB; however active TB still kills more than one million people each year. Increased urbanization, public health complacency, and immunity-weakening HIV have enabled the spread of TB in recent decades. Some strains are now extensively drug-resistant, virtually untreatable, and usually fatal.

An international team led by scientists at The Scripps Research Institute (TSRI) has identified a highly promising new anti-tuberculosis compound that killed over 99.9% of highly drug-resistant strains within three weeks.

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Professor Peter G. Schultz
Professor Peter G. Schultz
TSRI's collaborative approach to research is making headway in treating and curing deadly diseases. Leave a legacy of life-saving research by making a planned gift to TSRI.
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Associate Professor Matthew Disney
Associate Professor Matthew Disney
milestones in medical science:
Turning off Muscular Dystrophy

Myotonic dystrophy is an inherited disorder, the most common form of a group of conditions called muscular dystrophies that involve progressive muscle wasting and weakness. Myotonic dystrophy type 1 (MMD1) is the most common adult onset form of muscular dystrophy and is caused by a type of genetic RNA defect known as a "triplet repeat," a series of three nucleotides repeated more times than normal in an individual's genetic code.

For the first time, scientists from Scripps Florida, led by Associate Professor Matthew Disney, have identified small molecules that allow for complete control over the triplet repeat responsible for MMD1.

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Associate Professor Peiqing Sun and Hui Zheng
Research Associate Hui Zheng and Associate Professor Peiqing Sun
Other News:
Anti-cancer Mechanism Could Lead to New Treatments

A mechanism known as "oncogene-induced senescence" can block most cancer types, and is commonly seen when incipient skin cancers turn into slow-growing moles instead of malignant tumors. Tumors that achieve malignancy often do so by defeating or circumventing this barrier. However, scientists have been unable to find out precisely how the mechanism works – until now.

A research team at The Scripps Research Institute (TSRI) has uncovered how the interaction of three enzymes triggers a common type of oncogene-induced senescence. The ability to force this mechanism could create a new approach to treating cancer.

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More than $53,000 Raised Through Raffle for Alzheimer’s Research

Best-selling author Tess Gerritsen's raffle for the rights to name two characters in her next Rizzoli & Isles thriller raised more than $53,000 for TSRI's groundbreaking Alzheimer’s research. Two lucky donors to the campaign have been randomly chosen to name a new character and three runners-up received special Rizzoli & Isles prize packages.

If someone you love has suffered from Alzheimer's, you can continue to share your stories on Gerritsen's website and make a donation on her fundraising page.
facts & figures

More people are killed by tuberculosis each year than by any other infectious disease – more than by AIDS and malaria combined, according to the World Health Organization.
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