ÿþ<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40" xml:lang="en"> <head> <meta http-equiv=Content-Type content="text/html; charset=unicode"> <meta name=ProgId content=Word.Document> <meta name=Generator content="Microsoft Word 14"> <meta name=Originator content="Microsoft Word 14"> <link rel=File-List href="2011_11_files/filelist.xml"> <link rel=Edit-Time-Data href="2011_11_files/editdata.mso"> <!--[if !mso]> <style> v\:* {behavior:url(#default#VML);} o\:* {behavior:url(#default#VML);} w\:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} </style> <![endif]--> <title>At the Forefront</title> <!--[if gte mso 9]><xml> <o:DocumentProperties> <o:Author>Karla J. Martinez</o:Author> <o:Template>NormalEmail.dotm</o:Template> <o:LastAuthor>Karla J. Martinez</o:LastAuthor> <o:Revision>2</o:Revision> <o:TotalTime>1</o:TotalTime> <o:Created>2012-02-02T19:43:00Z</o:Created> <o:LastSaved>2012-02-02T19:53:00Z</o:LastSaved> <o:Pages>1</o:Pages> <o:Words>1128</o:Words> <o:Characters>6436</o:Characters> <o:Company>Microsoft</o:Company> <o:Lines>53</o:Lines> <o:Paragraphs>15</o:Paragraphs> <o:CharactersWithSpaces>7549</o:CharactersWithSpaces> <o:Version>14.00</o:Version> </o:DocumentProperties> <o:OfficeDocumentSettings> <o:AllowPNG/> </o:OfficeDocumentSettings> </xml><![endif]--> <link rel=themeData href="2011_11_files/themedata.thmx"> <link rel=colorSchemeMapping href="2011_11_files/colorschememapping.xml"> <!--[if gte mso 9]><xml> <w:WordDocument> <w:SpellingState>Clean</w:SpellingState> <w:GrammarState>Clean</w:GrammarState> <w:TrackMoves>false</w:TrackMoves> <w:TrackFormatting/> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:DoNotExpandShiftReturn/> <w:BreakWrappedTables/> <w:SplitPgBreakAndParaMark/> <w:EnableOpenTypeKerning/> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math"/> <m:brkBin m:val="before"/> <m:brkBinSub m:val="&#45;-"/> <m:smallFrac m:val="off"/> <m:dispDef/> <m:lMargin m:val="0"/> <m:rMargin m:val="0"/> <m:defJc m:val="centerGroup"/> <m:wrapIndent m:val="1440"/> <m:intLim m:val="subSup"/> <m:naryLim m:val="undOvr"/> </m:mathPr></w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="true" DefSemiHidden="true" DefQFormat="false" DefPriority="99" LatentStyleCount="267"> <w:LsdException Locked="false" Priority="0" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Normal"/> <w:LsdException Locked="false" Priority="9" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="heading 1"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 2"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 3"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 4"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 5"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 6"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 7"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 8"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 9"/> <w:LsdException Locked="false" Priority="39" Name="toc 1"/> <w:LsdException Locked="false" Priority="39" Name="toc 2"/> <w:LsdException Locked="false" Priority="39" Name="toc 3"/> <w:LsdException Locked="false" Priority="39" Name="toc 4"/> <w:LsdException Locked="false" Priority="39" Name="toc 5"/> <w:LsdException Locked="false" Priority="39" Name="toc 6"/> <w:LsdException Locked="false" Priority="39" Name="toc 7"/> <w:LsdException Locked="false" Priority="39" Name="toc 8"/> <w:LsdException Locked="false" Priority="39" Name="toc 9"/> <w:LsdException Locked="false" Priority="35" QFormat="true" Name="caption"/> <w:LsdException Locked="false" Priority="10" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Title"/> <w:LsdException Locked="false" Priority="1" Name="Default Paragraph Font"/> <w:LsdException Locked="false" Priority="11" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtitle"/> <w:LsdException Locked="false" Priority="22" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Strong"/> <w:LsdException Locked="false" Priority="20" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Emphasis"/> <w:LsdException Locked="false" Priority="59" SemiHidden="false" UnhideWhenUsed="false" Name="Table Grid"/> <w:LsdException Locked="false" UnhideWhenUsed="false" Name="Placeholder Text"/> <w:LsdException Locked="false" Priority="1" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="No Spacing"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 1"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 1"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 1"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 1"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 1"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 1"/> <w:LsdException Locked="false" UnhideWhenUsed="false" Name="Revision"/> <w:LsdException Locked="false" Priority="34" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="List Paragraph"/> <w:LsdException Locked="false" Priority="29" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Quote"/> <w:LsdException Locked="false" Priority="30" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Quote"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 1"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 1"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 1"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 1"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 1"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 1"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 1"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 1"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 2"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 2"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 2"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 2"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 2"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 2"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 2"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 2"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 2"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 2"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 2"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 2"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 2"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 2"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 3"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 3"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 3"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 3"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 3"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 3"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 3"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 3"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 3"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 3"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 3"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 3"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 3"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 3"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 4"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 4"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 4"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 4"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 4"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 4"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 4"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 4"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 4"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 4"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 4"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 4"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 4"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 4"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 5"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 5"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 5"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 5"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 5"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 5"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 5"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 5"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 5"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 5"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 5"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 5"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 5"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 5"/> <w:LsdException Locked="false" Priority="60" SemiHidden="false" UnhideWhenUsed="false" Name="Light Shading Accent 6"/> <w:LsdException Locked="false" Priority="61" SemiHidden="false" UnhideWhenUsed="false" Name="Light List Accent 6"/> <w:LsdException Locked="false" Priority="62" SemiHidden="false" UnhideWhenUsed="false" Name="Light Grid Accent 6"/> <w:LsdException Locked="false" Priority="63" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 1 Accent 6"/> <w:LsdException Locked="false" Priority="64" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Shading 2 Accent 6"/> <w:LsdException Locked="false" Priority="65" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 1 Accent 6"/> <w:LsdException Locked="false" Priority="66" SemiHidden="false" UnhideWhenUsed="false" Name="Medium List 2 Accent 6"/> <w:LsdException Locked="false" Priority="67" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 1 Accent 6"/> <w:LsdException Locked="false" Priority="68" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 2 Accent 6"/> <w:LsdException Locked="false" Priority="69" SemiHidden="false" UnhideWhenUsed="false" Name="Medium Grid 3 Accent 6"/> <w:LsdException Locked="false" Priority="70" SemiHidden="false" UnhideWhenUsed="false" Name="Dark List Accent 6"/> <w:LsdException Locked="false" Priority="71" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Shading Accent 6"/> <w:LsdException Locked="false" Priority="72" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful List Accent 6"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 6"/> <w:LsdException Locked="false" Priority="19" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis"/> <w:LsdException Locked="false" Priority="21" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Emphasis"/> <w:LsdException Locked="false" Priority="31" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Reference"/> <w:LsdException Locked="false" Priority="32" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Reference"/> <w:LsdException Locked="false" Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title"/> <w:LsdException Locked="false" Priority="37" Name="Bibliography"/> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading"/> </w:LatentStyles> </xml><![endif]--> <style> <!-- /* Font Definitions */ @font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-520092929 1073786111 9 0 415 0;} @font-face {font-family:Tahoma; panose-1:2 11 6 4 3 5 4 4 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-520081665 -1073717157 41 0 66047 0;} @font-face {font-family:Verdana; panose-1:2 11 6 4 3 5 4 4 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-1593833729 1073750107 16 0 415 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0in; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin;} a:link, span.MsoHyperlink {mso-style-noshow:yes; mso-style-priority:99; color:blue; text-decoration:underline; text-underline:single;} a:visited, span.MsoHyperlinkFollowed {mso-style-noshow:yes; mso-style-priority:99; color:purple; text-decoration:underline; text-underline:single;} p {mso-style-priority:99; mso-margin-top-alt:auto; margin-right:0in; mso-margin-bottom-alt:auto; margin-left:0in; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin;} p.MsoAcetate, li.MsoAcetate, div.MsoAcetate {mso-style-noshow:yes; mso-style-priority:99; mso-style-link:"Balloon Text Char"; margin:0in; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:8.0pt; font-family:"Tahoma","sans-serif"; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin;} span.BalloonTextChar {mso-style-name:"Balloon Text Char"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Balloon Text"; mso-ansi-font-size:8.0pt; mso-bidi-font-size:8.0pt; font-family:"Tahoma","sans-serif"; mso-ascii-font-family:Tahoma; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Tahoma; mso-bidi-font-family:Tahoma;} span.SpellE {mso-style-name:""; mso-spl-e:yes;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} @page WordSection1 {size:8.5in 11.0in; margin:1.0in 1.0in 1.0in 1.0in; mso-header-margin:.5in; mso-footer-margin:.5in; mso-paper-source:0;} div.WordSection1 {page:WordSection1;} --> </style> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="1026"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--> </head> <body bgcolor="#396EB2" lang=EN-US link=blue vlink=purple style='tab-interval: .5in'> <div class=WordSection1> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=800 style='width:600.0pt;mso-cellspacing:0in;background:#396EB2;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;background:white;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><a href="http://www.kintera.org/TR.asp?a=knJPKWNoE6KDKVL&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=knJPKWNoE6KDKVL&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=160 height=103 id="_x0000_i1039" src="https://www.kintera.com/AccountTempFiles/account106289/images/20110209LOGO.jpg" alt="Description: The scripps research institute"></span></a><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><a href="http://www.kintera.org/TR.asp?a=nqLVK5OAK9JKI5K&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=nqLVK5OAK9JKI5K&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=440 height=103 id="_x0000_i1038" src="https://www.kintera.com/AccountTempFiles/account106289/images/header.jpg" alt="Description: At the forefront"></span></a><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes; height:12.75pt'> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:12.75pt'></td> <td width=598 style='width:448.5pt;background:#D7D5D5;padding:0in 0in 0in 0in; height:12.75pt;background-origin: initial;background-clip: initial'></td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:12.75pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:2;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td valign=top style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=394 style='width:295.5pt;mso-cellspacing:0in;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=394 height=22 id="_x0000_i1037" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt="Description: Divider"></span><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Focus On </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:2;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=122 style='width:91.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><a href="http://www.kintera.org/TR.asp?a=qjJ1LePMIcIRKfJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=qjJ1LePMIcIRKfJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=150 height=192 id="_x0000_i1036" src="https://www.kintera.com/AccountTempFiles/account106289/images/brucebeutler.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/brucebeutler.jpg"></span></a><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Bruce <span class=SpellE>Beutler</span>, M.D., 2011 Nobel Laureate</span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>Giving thanks at Scripps Research</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#396EB2'><br> <br> The Scripps Research Institute is particularly grateful this Thanksgiving season to all the scientists, funders, and supporters who make our life-changing work possible. <br> <br> Our unique approach to biomedical research has resulted in a better understanding of and treatment for diseases that affect millions of people. Last month we were thrilled to hear that Bruce <span class=SpellE>Beutler</span>, chair of the Department of Genetics at Scripps Research and director of the Center for the Genetics of Host Defense at UT Southwestern Medical Center, was awarded the 2011 Nobel Prize for Physiology or Medicine.<br> <br> We couldn't be more grateful for his exceptional work  and generous friends like you who keep us moving towards the next breakthrough.<br> <br> <a href="http://www.kintera.org/TR.asp?a=knKPIWMoH6LGLYI&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=knKPIWMoH6LGLYI&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>Read reactions from Dr. <span class=SpellE>Beutler's</span> colleagues on his Nobel Prize win »</span></strong></a> </span><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:4;height:15.0pt'> <td style='padding:0in 0in 0in 0in;height:15.0pt'></td> </tr> <tr style='mso-yfti-irow:5'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=394 height=22 id="_x0000_i1035" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt="Description: Divider"></span><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:6'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Milestones in Medical Science </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:7;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:8'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=right style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:right; mso-table-top:middle;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td width=150 style='width:112.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><a href="http://www.kintera.org/TR.asp?a=nqIVI5OAJ9JNJ8L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=nqIVI5OAJ9JNJ8L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=150 height=193 id="_x0000_i1034" src="https://www.kintera.com/AccountTempFiles/account106289/images/griffin1.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/griffin1.jpg"></span></a><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Patrick R. Griffin, Professor and Department Chair at Scripps Florida <em><span style='font-family:"Verdana","sans-serif"'>(Photo by Lucien <span class=SpellE>Capehart</span>)</span></em></span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>Scientists Establish a New Class of Anti-Diabetic Compound</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'><br> <br> A new study out of The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute could lead to a new class of anti-diabetic therapeutics.<br> <br> <a href="http://www.kintera.org/TR.asp?a=qjK1JePMLcIULiK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=qjK1JePMLcIULiK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>Published in the journal </span></strong><em><b><span style='font-family:"Verdana","sans-serif"; color:#396EB2'>Nature</span></b></em><strong><span style='font-family: "Verdana","sans-serif";color:#396EB2'> in September, the study describes a new compound that targets a unique molecular switch that plays a role in the disease</span></strong></a>. The finding paves the way for new anti-diabetes drugs without the adverse side effects that plague current drugs like Avandia, which has raised concerns about increased risk of heart attack.<br> <br> <a href="http://www.kintera.org/TR.asp?a=tmL7KnMYKfL1JsJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=tmL7KnMYKfL1JsJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>Read More »</span></strong></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:9;height:15.0pt'> <td style='padding:0in 0in 0in 0in;height:15.0pt'></td> </tr> <tr style='mso-yfti-irow:10'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=394 height=22 id="_x0000_i1033" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt="Description: Divider"></span><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:11'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Other News </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:12;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:13'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=122 style='width:91.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><a href="http://www.kintera.org/TR.asp?a=mpJTK2OwE8KOL8L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=mpJTK2OwE8KOL8L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=149 height=204 id="_x0000_i1032" src="https://www.kintera.com/AccountTempFiles/account106289/images/baldwin.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/baldwin.jpg"></span></a><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Associate Professor Kristin Baldwin, Ph.D. <em><span style='font-family:"Verdana","sans-serif"'>(Photo by <span class=SpellE>BioMedical</span> Graphics)</span></em> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>Removing hurdles in stem cell techniques</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#396EB2'><br> <br> Stem cells made from patients' own cells hold tremendous promise for treating a wide range of diseases, but current reprogramming techniques have scientists worried about dangerous mutations.<br> <br> But a <a href="http://www.kintera.org/TR.asp?a=psKZLbPIKbJVIiK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=psKZLbPIKbJVIiK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>sophisticated new analysis of stem cell DNA</span></strong></a> by one of Scripps Research's young scientific stars shows that such fears may be unwarranted.<br> <br> &quot;We've shown that the standard reprogramming method can generate induced pluripotent stem cells that have very few DNA structural mutations,&quot; said Kristin Baldwin, Associate Professor at The Scripps Research Institute's <span class=SpellE>Dorris</span> Neuroscience Center.<br> <br> <a href="http://www.kintera.org/TR.asp?a=knJPKWNoE7KDKUL&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=knJPKWNoE7KDKUL&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>Read More »</span></strong></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:14;mso-yfti-lastrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <!-- RIGHT SIDE CONTENT --> <td valign=top style='background:#CCD9EB;padding:0in 0in 0in 0in; background-origin: initial;background-clip: initial'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#396EB2;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt;background-origin: initial; background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:white'>Facts &amp; Figures </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </td> </tr> <tr style='mso-yfti-irow:2;height:.75pt'> <td style='padding:0in 0in 0in 0in;height:.75pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#CCD9EB;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#CCD9EB;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial; background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>The Scripps Research Institute has received a four-star rating from Charity Navigator, thanks to our proven record of putting donor dollars directly toward our mission of finding treatments and cures for the most devastating human diseases through the creation of basic knowledge in the biosciences.</span><span style='mso-fareast-font-family: "Times New Roman"'> <o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:7.5pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height: 7.5pt'></td> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:4;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; background-origin: initial;background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:5'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#FA7C10;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:11.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:white'>The most important blessing </span><span style='mso-fareast-font-family:"Times New Roman"'><br> <br> </span><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman"'>When families gather to count their blessings, health often tops the list. Scripps Research scientists dedicate their lives to spreading the blessing of health to people across the globe. This year, do more than just say thank you  <a href="http://www.kintera.org/TR.asp?a=ngLVK5OAKaJKI4K&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=ngLVK5OAKaJKI4K&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:black'>help researchers ensure better health for generations to come.</span></strong></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:2;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><a href="http://www.kintera.org/TR.asp?a=qjJ1LePMIdIRKeJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=qjJ1LePMIdIRKeJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=116 height=33 id="_x0000_i1031" src="https://www.kintera.com/AccountTempFiles/account106289/images/donatenow.jpg" alt="Description: Donate now"></span></a><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:4;mso-yfti-lastrow:yes;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:6;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; background-origin: initial;background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:7'> <td style='background:#D7D5D5;padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#D7D5D5;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in'> <!--spacer--> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:11.25pt'> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <!--facebook button--> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><a href="http://www.kintera.org/TR.asp?a=knKPIWMoH7LGLXI&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=knKPIWMoH7LGLXI&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=145 height=38 id="_x0000_i1030" src="https://www.kintera.com/AccountTempFiles/account106289/images/20100526TSRIFACEBOOKBUTTON.jpg" alt="Description: Connect to us on facebook"></span></a><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <!--gray fade--> <tr style='mso-yfti-irow:2'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=20 height=30 id="_x0000_i1029" src="https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhiteleft.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhiteleft.jpg"></span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=145 height=30 id="_x0000_i1028" src="https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhitemiddle.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhitemiddle.jpg"></span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=20 height=30 id="_x0000_i1027" src="https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhiteleft.jpg" alt="Description: https://www.kintera.com/AccountTempFiles/account106289/images/2011atfwhiteleft.jpg"></span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <!--tell a friend--> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><a href="http://www.kintera.org/TR.asp?a=ngIVI5OAJaJNJ7L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=ngIVI5OAJaJNJ7L&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><span style='mso-fareast-font-family:"Times New Roman";mso-no-proof:yes; text-decoration:none;text-underline:none'><img border=0 width=163 height=34 id="_x0000_i1026" src="https://www.kintera.com/AccountTempFiles/account106289/images/tellafriend.jpg" alt="Description: Tell a friend"></span></a><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <!--spacer--> <tr style='mso-yfti-irow:4;mso-yfti-lastrow:yes;height:11.25pt'> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:8;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; background-origin: initial;background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:9;mso-yfti-lastrow:yes'> <td style='background:#CCD9EB;padding:0in 0in 0in 0in;background-origin: initial; background-clip: initial'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#CCD9EB;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:11.25pt'> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 11.25pt;background-origin: initial;background-clip: initial'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 11.25pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p><b><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; color:#396EB2'>Take Advantage of Tax Benefits While There's Still Time </span></b><br> <br> <span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; color:#396EB2'>At this time when the competition for diminished federal funding has increased, your support continues to be the lifeblood of our scientists' research. Help a friend, neighbor, or loved one today by making an investment in the future health of people worldwide.<br> <br> <a href="http://www.kintera.org/TR.asp?a=qjK1JePMLdIULhK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" href_cetemp="http://www.kintera.org/TR.asp?a=qjK1JePMLdIULhK&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>Any donation  no matter what the size  helps the cause, and those made before December 31 are tax deductible on 2011 tax returns.</span></strong></a> </span></p> </td> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes;height:7.5pt'> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 7.5pt'></td> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 7.5pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:4;height:.75pt'> <td style='padding:0in 0in 0in 0in;height:.75pt'></td> </tr> <tr style='mso-yfti-irow:5'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes; height:11.25pt'> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=598 style='width:448.5pt;background:#D7D5D5;padding:0in 0in 0in 0in; height:11.25pt;background-origin: initial;background-clip: initial'></td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:6;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='font-size:8.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>California: 10550 North Torrey Pines Road TPC2 - La Jolla CA 92037 - 858.784.2037 <br> Florida: 130 Scripps Way 4B2 - Jupiter FL 33458 - 561.228.2013 <br> email:&nbsp;<a href="mailto:philanthropy@scripps.edu" href_cetemp="mailto:philanthropy@scripps.edu"><b><span style='color:#396EB2'>philanthropy@scripps.edu</span></b></a> - <a href="http://www.kintera.org/TR.asp?a=tmL7KnMYKgL1JrJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK" target="_blank" href_cetemp="http://www.kintera.org/TR.asp?a=tmL7KnMYKgL1JrJ&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK"><b><span style='color:#396EB2'>www.supportcures.org</span></b></a></span><span style='mso-fareast-font-family:"Times New Roman"'> <o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes;height:33.75pt'> <td style='padding:0in 0in 0in 0in;height:33.75pt'></td> </tr> </table> </div> <p class=MsoNormal><span lang=EN style='mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN'><br> <br> <a href="http://www.kintera.org/TR.asp?a=knLPLWNoGcIQJ2J&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK">Remove yourself from this mailing</a>.<br> <br> <a href="http://www.kintera.org/TR.asp?a=ngIVL5OAIfLXLcI&amp;s=jtI1K6OMKiKNL1MLIrF&amp;m=kvJ0J9NULnIXLlK">Remove yourself from all mailings from The Scripps Research Institute</a>.<o:p></o:p></span></p> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"; mso-no-proof:yes'><img border=0 width=1 height=1 id="_x0000_i1025" src="http://omt.kintera.org/omt/5136039358.gif" alt="Description: http://omt.kintera.org/omt/5136039358.gif"></span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </div> </body> </html>