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mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="1026"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--> </head> <body bgcolor="#396EB2" lang=EN-US link=blue vlink=purple style='tab-interval: .5in'> <div class=Section1> <p class=MsoNormal style='margin-left:120.0pt;text-indent:-120.0pt;tab-stops: 120.0pt;mso-layout-grid-align:none;text-autospace:none'><o:p></o:p></p> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=800 style='width:600.0pt;mso-cellspacing:0in;background:#396EB2;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;mso-yfti-tbllook:1184'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'> <td style='padding:.75pt .75pt .75pt .75pt'> <p class=MsoNormal><span style='font-size:7.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:white'>February 2010 </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td style='padding:.75pt .75pt .75pt .75pt'> <p class=MsoNormal align=right style='text-align:right'><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:white'><a href="http://www.kintera.org/TR.asp?a=ioJPIQNsFfJIJZK&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='color:white'>View e-mail online</span></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:1;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;background:white;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=lhKVIZOELiIPK9J&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=160 height=103 id="_x0000_i1025" src="https://www.kintera.com/AccountTempFiles/account106289/images/atflogo.jpg" alt="The scripps research institute"></span></a><o:p></o:p></span></p> </td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=ouI1J8PQKlLWIjI&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=440 height=103 id="_x0000_i1026" src="https://www.kintera.com/AccountTempFiles/account106289/images/header.jpg" alt="At the forefront"></span></a><o:p></o:p></span></p> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes; height:12.75pt'> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:12.75pt'></td> <td width=598 style='width:448.5pt;background:#D7D5D5;padding:0in 0in 0in 0in; height:12.75pt;background-origin: initial;background-clip: initial'> <p class=MsoNormal align=center style='text-align:center'><b><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#666666'>An e-Newsletter for Philanthropists </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:12.75pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:2;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td valign=top style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=394 style='width:295.5pt;mso-cellspacing:0in;mso-yfti-tbllook: 1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><img border=0 width=394 height=22 id="_x0000_i1027" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt=Divider><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:1;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:2'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Focus On: </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:3;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:4'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=122 style='width:91.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=hdJNKNNoEeKJKZL&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=122 height=165 id="_x0000_i1028" src="https://www.kintera.com/AccountTempFiles/account106289/images/201002sharpless.jpg"></span></a></span><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Nobel laureate <br> K. Barry Sharpless </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>Things just click for Nobel chemist Barry Sharpless</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#396EB2'><br> <br> Barry Sharpless's brain doesn't work like the rest of ours. As he describes &quot;click chemistry,&quot; the game-changing chemical philosophy he introduced in 2001, the Nobel Prize-winning chemist weaves together references as varied as: Billie Holiday, Manhattan Project physicist Richard Feynman, Muhammad Ali, computer games, and trompe l oeil Internet videos. His methods aren't like other scientists', either. He doesn't believe you can brainpower your way to making significant discoveries; Sharpless says he tries to seduce Lady Luck, to set the stage for Serendipity. <br> <br> He makes you feel like a partner in crime as he talks, like you're in on the secret even though you haven't the faintest idea what he's talking about... until, in a single, glimmering sentence, he pulls the disparate threads into a perfect bow. <br> <br> <a href="http://www.kintera.org/TR.asp?a=kqLTKWOAKhJQI9K&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>If this is how he puts together words, just imagine what he does with enzymes, atoms, and chemical bonds</span></strong></a>. </span><span style='mso-fareast-font-family: "Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:5;height:15.0pt'> <td style='padding:0in 0in 0in 0in;height:15.0pt'></td> </tr> <tr style='mso-yfti-irow:6'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><img border=0 width=394 height=22 id="_x0000_i1029" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt=Divider><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:7;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:8'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Milestones in Medical Science: </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:9;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:10'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=right style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:right; mso-table-top:middle;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td width=122 style='width:91.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=njJZL5PMIkIXKjJ&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=122 height=153 id="_x0000_i1030" src="https://www.kintera.com/AccountTempFiles/account106289/images/201002kodadek.jpg"></span></a></span><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Professor <br> Thomas Kodadek </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>New tactics on MS and autoimmune diseases</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#396EB2'><br> <br> Finding treatments for autoimmune diseases like Multiple Sclerosis is a precarious balancing act. Unlike many diseases, doctors aren't fighting intruders, but rogue elements of the body's own immune system. Just as insurgents will hide themselves amongst civilians, so too do these elements blend in with the good guys. <br> <br> Four decades of research focused on antigens  molecules that can kick-start an immune response  has been focused on trying to sort the good from the bad. Enough was enough for Scripps Research scientist Thomas Kodadek. <a href="http://www.kintera.org/TR.asp?a=hnKNINMoHeLML2I&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><strong><span style='font-family:"Verdana","sans-serif";color:#396EB2'>His outside-the-box thinking has produced exciting initial results that just might hold the key to developing new therapies</span></strong></a>. </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:11;height:15.0pt'> <td style='padding:0in 0in 0in 0in;height:15.0pt'></td> </tr> <tr style='mso-yfti-irow:12'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><img border=0 width=394 height=22 id="_x0000_i1031" src="https://www.kintera.com/AccountTempFiles/account106289/images/divider.jpg" alt=Divider><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:13;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:14'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><b><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Other News: </span></b><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:15;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:16'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=122 style='width:91.5pt;padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=kgITIWOAJhJTJcL&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=122 height=153 id="_x0000_i1032" src="https://www.kintera.com/AccountTempFiles/account106289/images/201002mueller.JPG"></span></a></span><span style='font-size:7.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>Professor <br> Ulrich Mueller </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:3.75pt'> <td colspan=2 style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> </table> <p class=MsoNormal><strong><span style='font-size:9.0pt;font-family: "Verdana","sans-serif";mso-fareast-font-family:"Times New Roman"; color:#396EB2'>Finding the Deafness Gene</span></strong><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman";color:#396EB2'><br> <br> What if you could take a drug that would slow, stop, or prevent hearing-loss? <br> <br> It's a tantalizing possibility, not only for the 36 million Americans already suffering from hearing loss, but for the millions more who stand to lose hearing as they age.<br> <br> <a href="http://www.kintera.org/TR.asp?a=plL3LbMULnKVLiI&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='color:#396EB2'><stron g="">Scripps Research's Ulrich Mueller and his team took a big step towards this possibility in the past few months as they pinpointed a new gene related to deafness</span></strong></a>. </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:17;mso-yfti-lastrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <!-- RIGHT SIDE CONTENT --> <td valign=top style='background:#CCD9EB;padding:0in 0in 0in 0in; background-origin: initial;background-clip: initial'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#396EB2;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt;background-origin: initial; background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='mso-cellspacing:0in;mso-yfti-tbllook:1184; mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical: paragraph;mso-table-anchor-horizontal:column;mso-table-left:left; mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow: yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:10.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:white'>Facts &amp; Figures </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> </table> </td> </tr> <tr style='mso-yfti-irow:2;height:.75pt'> <td style='padding:0in 0in 0in 0in;height:.75pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#CCD9EB;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:3.75pt'> <td style='padding:0in 0in 0in 0in;height:3.75pt'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#CCD9EB;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial; background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>Our distinguished faculty includes <strong><span style='font-family: "Verdana","sans-serif"'>3</span></strong> Nobel laureates, <strong><span style='font-family:"Verdana","sans-serif"'>17</span></strong> members of the National Academy of Sciences, <strong><span style='font-family:"Verdana","sans-serif"'>9</span></strong> members of the National Institute of Medicine, <strong><span style='font-family:"Verdana","sans-serif"'>15</span></strong> members of the American Academy of Arts and Sciences, <strong><span style='font-family:"Verdana","sans-serif"'>4</span></strong> members of the American Philosophical Society, <strong><span style='font-family:"Verdana","sans-serif"'>17</span></strong> American Association for the Advancement of Science fellows, <strong><span style='font-family:"Verdana","sans-serif"'>3</span></strong> recipients of the Wolf Prize in Chemistry, and <strong><span style='font-family:"Verdana","sans-serif"'>3</span></strong> recipients of the California Scientist of the Year Award. </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes;height:7.5pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height: 7.5pt'></td> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:4;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; background-origin: initial;background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:5'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#FA7C10;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:11.5pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:white'>Supporting the next big idea </span><span style='mso-fareast-font-family:"Times New Roman"'><br> <br> </span><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman"'>In the late 1980s, before Barry Sharpless won the 2001 Nobel Prize for Chemistry, he couldn't find a funder for his next big idea  until he came to Scripps Research. Now that idea stands to revolutionize the field of drug creation. <br> <br> <a href="http://www.kintera.org/TR.asp?a=ioJPIQNsFgJIJYK&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='color:white'>Your donation today could uncover the next big idea.</span></a></span><span style='mso-fareast-font-family:"Times New Roman"'> <o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:2;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=lhKVIZOELjIPK8J&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=116 height=33 id="_x0000_i1033" src="https://www.kintera.com/AccountTempFiles/account106289/images/donatenow.jpg" alt="Donate now"></span></a><o:p></o:p></span></p> </td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:4;mso-yfti-lastrow:yes;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:6;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; background-origin: initial;background-clip: initial'></td> </tr> <tr style='mso-yfti-irow:7'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;background:#D7D5D5;mso-yfti-tbllook:1184; mso-padding-alt:0in 0in 0in 0in;background-origin: initial;background-clip: initial'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:11.25pt'> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in'></td> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman"'>Share this with a friend: </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:2;height:11.25pt'> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=20 style='width:15.0pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> <tr style='mso-yfti-irow:3'> <td colspan=3 style='padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='mso-fareast-font-family:"Times New Roman"'><a href="http://www.kintera.org/TR.asp?a=ouI1J8PQKmLWIiI&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH"><span style='text-decoration:none;text-underline:none'><img border=0 width=163 height=34 id="_x0000_i1034" src="https://www.kintera.com/AccountTempFiles/account106289/images/tellafriend.jpg" alt="Tell a friend"></span></a><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:4;mso-yfti-lastrow:yes;height:11.25pt'> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=10 style='width:7.5pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:8;height:.75pt'> <td style='background:white;padding:0in 0in 0in 0in;height:.75pt; 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color:#396EB2'>Upcoming Event </span></strong><span style='mso-fareast-font-family: "Times New Roman"'><br> <br> </span><span style='font-size:9.0pt;font-family:"Verdana","sans-serif"; mso-fareast-font-family:"Times New Roman";color:#396EB2'>We invite our donors to join us for a lively panel discussion about the newest research aimed at maintaining our quality of life as we age. Presented by scientists from the Department of Metabolism and Aging at Scripps Florida.<br> <br> Monday March 22<br> 5:00 7:00 PM<br> 120 Scripps Way, Building B<br> Jupiter, Florida<br> <br> RSVP to 561-228-2015 or <a href="mailto:lhuertas@"><span style='color:#396EB2'>lhuertas@scripps.edu</span></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in'></td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes;height:11.25pt'> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 11.25pt'></td> <td style='padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=15 style='width:11.25pt;padding:0in 0in 0in 0in;height: 11.25pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:4;height:.75pt'> <td style='padding:0in 0in 0in 0in;height:.75pt'></td> </tr> <tr style='mso-yfti-irow:5'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt: 0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes; height:11.25pt'> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:11.25pt'></td> <td width=598 style='width:448.5pt;background:#D7D5D5;padding:0in 0in 0in 0in; height:11.25pt;background-origin: initial;background-clip: initial'></td> <td width=1 style='width:.75pt;padding:0in 0in 0in 0in;height:11.25pt'></td> </tr> </table> </div> </td> </tr> <tr style='mso-yfti-irow:6;mso-yfti-lastrow:yes'> <td style='padding:0in 0in 0in 0in'> <div align=center> <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='mso-cellspacing:0in;mso-yfti-tbllook:1184;mso-padding-alt:0in 0in 0in 0in'> <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> <tr style='mso-yfti-irow:1'> <td style='padding:0in 0in 0in 0in'> <p class=MsoNormal align=center style='text-align:center'><span style='font-size:8.5pt;font-family:"Verdana","sans-serif";mso-fareast-font-family: "Times New Roman"'>California: 10550 North Torrey Pines Road TPC2 - La Jolla CA 92037 - 858.784.2037 <br> Florida: 130 Scripps Way 4B2 - Jupiter FL 33458 - 561.228.2015 <br> email:&nbsp;<a href="mailto:philanthr"><strong><span style='font-family: "Verdana","sans-serif"'>philanthropy@scripps.edu</span></strong></a> - <a href="http://www.kintera.org/TR.asp?a=hdJNKNNoEfKJKYL&amp;s=isLZJ3NIKhKLKYOHKqH&amp;m=khJMLTPxE9IWH" target="_blank"><strong><span style='font-family:"Verdana","sans-serif"'>www.supportcures.org</span></strong></a> </span><span style='mso-fareast-font-family:"Times New Roman"'><o:p></o:p></span></p> </td> </tr> <tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes;height:7.5pt'> <td style='padding:0in 0in 0in 0in;height:7.5pt'></td> </tr> </table> </div> </td> </tr> </table> </div> </td> </tr> </table> </div> <p class=MsoNormal><span lang=EN style='mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN'><br> <o:p></o:p></span></p> <p class=MsoNormal><span style='mso-fareast-font-family:"Times New Roman"'><img border=0 width=1 height=1 id="_x0000_i1035" src="http://omt.kintera.org/omt/3169107675.gif"><o:p></o:p></span></p> </div> </body> </html>