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Facts at a Glance
The Institute
In 1961, a handful of immunologists from the University of Pittsburgh
founded what was to become The Scripps Research Institute (TSRI).
Their intention was to establish a creative and productive scientific
environment where research could flourish without the usual constraints
of a traditional academic setting. Today, TSRI is the largest private,
non-profit biomedical research organization in the world. In 1989,
TSRI took the bold step of extending and building on its prodigious
reputation for excellence in basic biomedical research by establishing
an innovative doctoral program unlike any other in the United States.
Combining its unique strength in the integration of such disciplines
as cell and molecular biology, structure and chemistry, it developed
a Graduate Program in Macromolecular and Cellular Structure and Chemistry.
And in an effort to draw upon the superior capabilities of a recently
assembled chemistry faculty with an outstanding record of achievement
in contemporary areas of chemical, biological and structural research,
a doctoral program in chemistry was established three years later.
In 2002, TSRI named its graduate college The Kellogg School of Science
and Technology for philanthropists Janet R. ("Jean") and
W. Keith Kellogg II, who have been long-standing patrons of education
and science.
In 2003, a comprehensive review of the curriculum resulted in the
redefined Doctoral Program in Chemical and Biological Sciences emphasizing
the interdisciplinary nature of the program and reflecting the particular
strengths of the Institue. This change allows students to select one
of four curricular tracks–chemistry, chemical biology, biophysics
or biology–and acknowledges the faculty's and student's views that
future scientists must be broadly trained in these areas of scientific
inquiry.
Philosophy
The philosophy of The Scripps Research Institute emphasizes the education
and training of researchers in biology and chemistry preparing to
meet the scientific challenges of the next century; the creation of
basic knowledge in the biological and chemical sciences for the application
of medical and material discoveries; and the pursuit of fundamental
scientific advances through interdisciplinary programs and collaborations.
It is within the framework of this overarching mission that the students
in the Graduate Program learn in an environment tailored to accommodate
individual interests and capabilities.
Location
The Scripps Research Institute is located in La Jolla, California,
approximately 15 miles north of the city of San Diego. Located within
a two-mile radius of TSRI, The Neurosciences Institute, the University
of California at San Diego, The Salk Institute, The Burnham Institute for Medical Research,
and the Genomics Institute of the Novartis Research Foundation, as
well as a large concentration of biotechnology and pharmaceutical
companies, provide a research environment that is considered to be
one of the finest in the world.
Majors and Degrees
TSRI's Kellogg School of Science and Technology offers a Doctoral
Program in Chemical and Biological Sciences. Generally, the program
will culminate with the Ph.D. degree after approximately five years
of study and research.
Faculty
The research interests and activities of
the TSRI faculty span a broad range of fields in biology and chemistry,
assuring each student numerous opportunities for specialization
as the graduate education progresses. The considerable overlap in
areas of interest and expertise promotes the concept of interdisciplinary
collaborations and the free exchange of ideas. This investigative
synergy is at the heart of the Graduate Program's philosophy of
education. The Institute's staff includes more than 225 professors,
800 postdoctoral fellows, 743 laboratory technicians and 815 administrative
services employees. The full time faculty of 225 includes 15 members
of the National Academy of Sciences and three Nobel Laureates. Widely
recognized in the international scientific arena, many are the recipients
of prestigious honors and awards, including the following:
Nobel Laureates
Gerald M. Edelman, M.D., Ph.D.
K. Barry Sharpless, Ph.D.
Kurt Wüthrich, Ph.D.
Members, National Academy of Sciences
Bruce Beutler, M.D.
Ernest Beutler, M.D.
Floyd E. Bloom, M.D.
Francis V. Chisari, M.D.
Gerald M. Edelman, M.D., Ph.D.
Albert Eschenmoser, Ph.D.
Gerald F. Joyce, M.D., Ph.D.
Richard A. Lerner, M.D.
K.C. Nicolaou, Ph.D.
Michael B.A. Oldstone, M.D.
Julius Rebek, Jr., Ph.D.
Paul Schimmel, Ph.D.
Peter Schultz, Ph.D.
K. Barry Sharpless, Ph.D.
Peter K. Vogt, Ph.D.
Charles Weissmann, M.D., Ph.D.
Michael B. Oldstone, M.D.
Chi-Huey Wong, Ph.D.
Peter Wright, Ph.D.
Kurt Wüthrich, Ph.D.
Members, National Institute of Medicine
Floyd E. Bloom, M.D.
Francis V. Chisari, M.D.
Thomas S. Edgington, M.D.
Richard A. Lerner, M.D.
Peter Schultz, Ph.D.
Eric J. Topol, M.D.
Peter K. Vogt, Ph.D.
Members, American Academy of Arts and
Sciences
Ernest Beutler, M.D.
Floyd E. Bloom, M.D.
Dale L. Boger, Ph.D.
Gerald M. Edelman, M.D., Ph.D.
Richard A. Lerner, M.D.
K.C. Nicolaou, Ph.D.
Julius Rebek, Jr., Ph.D.
Paul Schimmel, Ph.D.
Peter Schultz, Ph.D.
K. Barry Sharpless, Ph.D.
Peter K. Vogt, Ph.D.
Charles Weissmann, M.D., Ph.D.
Ian W. Wilson, Ph.D.
Chi-Huey Wong, Ph.D.
Peter E. Wright, Ph.D.
Kurt Wüthrich, Ph.D.
Members, American Philosophical Society
Floyd E. Bloom, M.D.
Gerald M. Edelman, M.D., Ph.D.
Paul Schimmel, Ph.D.
Peter Vogt, Ph.D.
Fellows, American Association for the
Advancement of Science
Dale L. Boger, Ph.D.
Michael Buchmeier, Ph.D.
Gerald M. Edelman, M.D., Ph.D.
Thomas S. Edgington, M.D.
M. Reza Ghadiri, Ph.D.
Kim D. Janda, Ph.D.
George Koob, Ph.D.
Richard A. Lerner, M.D.
Donald E. Mosier, M.D., Ph.D.
K.C. Nicolaou, Ph.D.
Michael B. Oldstone, M.D.
Julius Rebek, Jr., Ph.D.
Paul Schimmel, Ph.D.
Sandra L. Schmid, Ph.D.
K. Barry Sharpless, Ph.D.
Eng M. Tan, M.D.
Peter E. Wright, Ph.D.
Recipients, Wolf Prize in Chemistry
Richard A. Lerner, M.D.
Peter Schultz, Ph.D.
K. Barry Sharpless, Ph.D.
Recipients, California Scientist of
the Year Award
Albert Eschenmoser, Ph.D.
Richard A. Lerner, M.D.
Peter Schultz, Ph.D.
Peter K. Vogt, Ph.D.
Faculty by Department/Component
| California Campus |
| Cell Biology |
23 |
| Chemical Physiology |
8 |
| Chemistry |
23 |
| Committee on the Neurobiology of Addictive Disorders |
8 |
| Genetics |
1 |
| Immunology & Microbial Science |
35 |
| Molecular Biology |
37 |
| Molecular & Experimental Medicine |
30 |
| Molecular & Integrative Neuroscience |
13 |
| Neurobiology |
5 |
| Faculty and Professional Staff - Florida Campus |
|
| Cancer Biology |
8 |
| Chemistry |
3 |
| Infectology |
5 |
| Metabolism & Aging |
1 |
| Molecular & Integrative Neurosciences |
1 |
| Molecular Therapeutics |
4 |
| Translational Research Institute |
21 |
Employees
| California |
| Faculty |
Research Associates |
Graduate Students |
Technical & Support Services Employees |
| 223 |
662 |
250 |
1307 |
| Florida |
| Faculty |
Research Associates |
Graduate Students |
Technical & Support Services Employees |
| 57 |
67 |
11 |
147 |
Academic Facilities
The TSRI campus consists of multiple laboratory buildings on Torrey
Pines Mesa with more than one million square feet of space overlooking
the Pacific. The Institute enjoys one of the world's leading private
computational capabilities with an array of computers, including a
Cray supercomputer. Research is further supported by X-ray crystallography
laboratories, high performance NMR spectrometry including a state-of-the
art 900 MHz instrument electron microscopy, optical spectroscopy,
a centralized DNA sequencing laboratory and a fluorescence activated
cell sorting facility. The Kresge Library maintains a wide range of
periodicals covering scientific and clinical topics, as well as selected
reference volumes and books. The library maintains access to a variety
of on-line services for computerized database searching. Library users
have direct access to the MEDLINE database and CAS on-line.
Student Population
The total TSRI graduate student population for the academic year 2008/2009
is 250.
Academic Programs
The newly designed program offers students the opportunity to select
one of five curricular tracks–chemistry, chemical biology, biophysics, biology, and Immunology–each having required coursework and suggested electives.
Students, in consultation with their advisor and committee, may collectively
customize their elective curriculum as well. The required courses
ensure that students in each track have a common educational background,
as well as a solid foundation from which to build. The electives
accommodate individual flexibility, enabling students to diversify
their scientific studies and explore areas of interest at a much greater
depth of understanding.
Ranking
In 2007, U.S. News & World Report ranked Scripps Research in the top 10 of America's Best Graduate Schools. Scripps Research was ranked 6th in chemistry and 8th in biological sciences. Under chemistry specialties, Scripps Research was ranked #6 for organic chemistry. In the category of biological sciences specialties, Scripps Research was ranked #16 for cell biology and #13 for molecular biology.
Admission Prerequisites
The Kellogg School of Science and Technology accepts applications
from individuals earning a bachelor's degree, or the equivalent.
Applicants have been admitted with a wide variety of backgrounds,
including degrees in Chemistry, Biology, Physics, Chemical Engineering,
as well as other disciplines.
Candidates applying to the Chemistry, Biology, Chemical Biology,
and Biophysics Tracks are expected to have taken core scientific
courses in their discipline, as well as advanced coursework in their
area of specialization.
Due to the interdisciplinary and broad nature of the TSRI program,
there are no specific course prerequisites, however, applicants
should ensure that they have adequate preparation to pass the TSRI
course requirements in one of the four Tracks.
Guidelines for Academic Preparation
The Admissions Committee will determine if the applicant has the
appropriate academic background for their chosen Track. TSRI will
consider outstanding applicants with diverse backgrounds on an individual
basis. However, most successful applicants will have preparation
that falls into the following guidelines:
- Students should have completed AT LEAST two of the following
four general courses:
- one year of general biology
- one year of general physics
- one year of general chemistry
- one year of mathematics (calculus and differential equations)
- Students should have taken at least four semesters distributed
among the following advanced subjects:
- cell biology
- developmental biology
- molecular genetics
- organic chemistry
- biophysics
- macromolecular structure
- physical chemistry
- biochemistry
- Students should have taken laboratory courses in at least three
of the following subjects:
- biology
- biochemistry
- chemistry
- physics
- Students should have one or two years of research laboratory
experience.
Tuition and Fees
Financial support for graduate students is provided by TSRI,
the student's advisor, and through national fellowships. This support
covers the student's stipend and the cost of education. The 2008/2009
graduate student stipend has been set at $26,000. Students who receive
a competitive fellowship may be eligible for a supplement. All fees,
required texts, as well as health insurance costs will be borne by
TSRI.
Application and Information
The application should include official transcripts from all colleges
and/or universities attended, both general and applicable subject
graduate record exam (GRE) scores, a minimum of three letters of recommendation,
and a personal statement. The statement should include a detailed
description of prior research experience, the purpose for entering
a Ph.D. program, and the specific reasons for choosing The Scripps
Research Institute's Graduate Program. International students must
submit evidence of proficiency in English (TOEFL). All application
materials must be received by January 1 to be considered for admission
into the Program in August of the same year.
Accreditation
The Scripps Research Institute is accredited by the Accrediting Commission
for Senior Colleges and Universities of the Western Association of
Schools and Colleges, 985 Atlantic Avenue, Suite 100, Alameda, CA
94501, (510) 748-9001, an institutional accrediting body recognized
by the Council for Higher Education Accreditation and the U. S. Department
of Education.
Application Deadline
An application for admission must be postmarked by January 1. Application
forms are available from the web site, or by contacting the Office
of Graduate Studies, 10550 N. Torrey Pines Road, TPC-19, La Jolla,
California 92037, telephone: 858-784-8469, fax: 858-784-2802, email:
gradprgm@scripps.edu. There is no application fee. Applications are
reviewed by an admissions committee; successful candidates will be
invited to the Institute for an interview in February or March.
Education Programs
Postdoctoral Fellows
TSRI has maintained its commitment to training the next generation
of scientists, in part, by its active recruitment of postdoctoral
fellows, all of whom have completed postgraduate degrees. They continue
their scientific training in TSRI's laboratories for a period of two
to five years under the supervision of the senior scientific staff.
They contribute to ongoing research inquiries and are named authors
on numerous scientific publications.
Educational Outreach
TSRI has a local and national commitment to guide young students and
provide them with opportunities to explore and pursue educational
and career opportunities in the sciences. Toward this end, funded
through grants and private philanthropy, the Institute provides a
variety of programs for students at the high school and college levels
and for middle school and high school science teachers to participate
in research activities on the campus. These programs are designed
and supervised by many of TSRI's graduate students and senior scientists.
While students of all ethnic and cultural groups are accepted into
the programs, a special emphasis is placed on identifying and recruiting
students who are historically underrepresented in the sciences.
Campus Facilities
TSRI's facilities are located on approximately 35 acres of land of
which 14.7 are owned by TSRI. The campus is within close proximity
to the University of California, San Diego, in La Jolla, California.
This location provides access to San Diego's scientific community,
which includes The Salk Institute and the Burnham Institute, as well
as a concentration of some 300 biotechnology companies.
The campus includes leased and owned space. TSRI owns facilities,
including approximately 410,500 square feet of laboratory space. Additionally
the Institute leases some 573,500 square feet of laboratory space
in 12 buildings and approximately 60,800 square feet of administrative
space in three buildings.
Technical Support Capabilities
The research activities of TSRI's scientists require significant technical
support, including research computing, NMR spectroscopy, particle
beam spectroscopy, mass spectroscopy, optical spectroscopy, a fluorescence
activated cell sorting facility, x-ray crystallography laboratories,
electron microscopy, bioinformatics, and DNA array protein chip technology.
NMR spectrometers are housed in the Aline W. and L.S. Skaggs NMR Building
and the Buddy Taub Center for Molecular Structure and Design.
Computer and Network Facilities
The Institute maintains central computing resources which include a large shared memory SGI Linux machine (yellowtail), and two 64-bit LINUX clusters bluefish and garibaldi. The SGI LINUX machine is a 128 CPU 1.3 Ghz Itanium-2 SGI 3700 server, with 128 GBytes of memory and one Terabyte of local disk space. The bluefish LINUX cluster contains 576 3.4 GHZ Intel XEON-EMT processors for computations and additional Intel XEON-EMT processors for system functions. The garibaldi LINUX cluster contains 1200 2.33 GHZ Intel dual core XEON-EMT processors and 620 3.4 GHZ Intel single core XEON-EMT for a total of 3020 cpu's available for computations. The garibaldi cluster uses additional Intel dual core XEON-EMT processors for system functions. Between local and shared disks each of these clusters has over sixty Terabytes of disk space available for computational data. These systems use the PBS batch queueing system to ensure maximum system throughput and fair access.
An extensive data communications network connects 14 buildings on campus. The major compute and data servers are connected via Fast Ethernet switches and numerous high speed routers with selective use of gigabit ethernet. The majority of workstations, personal computers, and smaller compute servers are connected by 10 & 100 Megabit switched and routed ethernets.
This network links together approximately 4900 computers. Approximately 600 of these are high-end Unix based graphics workstations, largely represented by Linux/Intel, Silicon Graphics and Sun Microsystems. Other Unix workstations include Compaq and Hewlett-Packard. The other computers are equally divided between Windows and Macintosh desktop computers.
The Institute operates a central data archival facility which uses a Silicon Graphics Altix 350 server, a thirty five Terabyte disk cache, and a large high speed StorageTek tape library. Current capacity is approximately 2500 Terabytes.
The Institute operates a central backup facility which provides periodic full backups and daily incremental backups of computer systems. The system uses a number of servers and two tape libraries housed in two buildings to provide disaster recovery.
Various groups within the Institute maintain hardcopy output devices which include a Solitaire film recorder and numerous color and B/W laser printers.
Off campus resources such as massively parallel computers at various Supercomputer Centers are accessible via a full duplex 100 Megabit fast ethernet Internet connection.
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