TSRI Faculty Interests

Obesity

Balch, William E. 
is interested in the biochemical and molecular basis for vesicular trafficking from the endoplasmic reticulum to the cell surface, particularly in the structures, functions, and mechanisms of control exerted by small GTP-binding proteins.

Janda, Kim  
Investigates biological catalysts, development of methods for the detection of and protection against chemical/biological warfare agents, combinatorial chemical libraries, synthesis and evaluation of enzyme inhibitors, solid-phase organic synthesis, quorum sensing within bacterial systems, lead discovery and detection strategies for tropical diseases, antibody/peptide phage display libraries, cell-penetrating peptides as therapeutic delivery vehicles, and the application of immunopharmacotherapy in the treatment of drug addiction, cancer and obesity.

Kralli, Anastasia  
focuses on the mechanism of action of nuclear receptor coactivators that modulate transcriptional responses to small lipophilic hormones and confer specificity to hormone signaling.

Saez, Enrique  
is interested in two broad themes related to the regulation of energy balance in mammals.