TSRI Faculty Interests

Molecular Recognition and Nanofabrication

Fokin, Valery  
develops preactical catalytic transformations for organic synthesis, combinatorial chemistry, chemical biology, and materials research; searches for novel antiviral agents, nicotinic receptor ligands, and protease inhibitors.

Gottesfeld, Joel  
is concerned with protein-DNA interactions involved in the transcriptional regulation in animal cells and the development of small molecule inhibitors and activators of gene expression.

Joyce, Gerald  
studies the test-tube evolution of RNA and DNA enzymes, both to explore their potential biomedical applications and to examine their possible role in the early history of life on Earth.

Rebek Jr., Julius  
studies basic questions of molecular recognition, self-assembly, catalysis, and complementarity by designing novel organic molecular nanocapsules and synthetic receptors.

Tainer, John  
develops and applies advanced tools for high-impact structural biology including combined x-ray scattering in solution and x-ray crystallography on complexes at his synchrotron beamline to bridge from complexes and conformations to pathways and phenotypes by characterizing macromolecular machines, novel inhibitors, and the molecular basis for diseases and intervention strategies.